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Study sheds light on cancer susceptibility and disease involving bone-marrow failure

Defective protein production can occur in cells even when the genes controlling those proteins are normal, according to a new study to be published May 12 in Science.

12 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

Scientists unlock more secrets of HIV and SARS

UK scientists have cracked one of the key biological processes used by viruses such as HIV and SARS when they replicate according to a paper published in the journal Nature tomorrow (11 May). Viruses are able to interfere with the host cell processes that our bodies use to replicate cells, and protein synthesis is often one of their targets.

10 May 2006

DNA taxi

Despite few successes to date, gene therapy is a highly promising approach for medical therapy in the future.

1 May 2006

Microarray analysis could lead to better understanding of mechanisms underlying the genetic propensity toward excessive drinking

The meta analysis, which examined more than 4.5 million data points on more than 100 microarrays from mouse models, also identified more than 1,300 functional groups, including signaling and transcription pathways, which may also play an important role in establishing a capacity for a "high level of alcohol consumption."

18 Apr 2006

Epstein-Barr virus infection linked to multiple sclerosis

Young adults with high levels of antibodies against the Epstein-Barr virus, the virus that most often causes mononucleosis, may be more likely to develop multiple sclerosis 15 to 20 years later, according to a study in the Archives of Neurology.

11 Apr 2006

Wobble pairs make RNA more reactive

The wealth of information contained in a strand of genetic material boils down to sequences of matched pairs of nucleotides that cellular machinery decodes to construct proteins.

13 Mar 2006

MIT researchers capture virus in extraordinary detail

Fifty years after MIT researchers pioneered the use of electron microscopy to study viruses, MIT scientists have helped produce the most detailed images yet of the tiny infectious agents.

21 Feb 2006

New understanding of the molecular genetics of successful fertilization

A new paper in the February 15th issue of Genes & Development lends novel insight into the cellular changes that occur in sperm while they reside in the female reproductive tract - providing a new understanding of the molecular genetics of successful fertilization.

14 Feb 2006

Intracellular observation of RNA metabolism will help identify disease-associated RNAs

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe-in real-time-the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions.

7 Feb 2006

HHS awards $56.9 million to tackle health disparities

HHS Secretary Mike Leavitt has announced the awarding of $56.9 million by the National Institutes of Health’s (NIH) National Center on Minority Health and Health Disparities (NCMHD).

10 Jan 2006

University of Michigan Medical School to study the science of obesity and metabolism

As millions of Americans prepare their New Year’s resolutions to lose weight, eat better or exercise more, the University of Michigan Medical School is launching a new center that may help explain why so many resolutions fail, while others succeed.

29 Dec 2005

Children could be saved from neuroblastoma using antibody therapy

Combination of T cell, antibody to neuroblastoma cells and molecule that spurs T cell growth is designed to treat low initial tumor levels or small cancer cell populations that survive initial treatment, according to St. Jude.

22 Dec 2005

Analysis of the regulatory hurdles in European Diagnostics

In a move aimed at harmonising diagnostics regulations, the European parliament amended the medical devices directive (MDD) of 1993 to bring in the IVD directive (98/79/EC) in 1998.

6 Dec 2005

Exploiting biology's own chemical toolbox...

Exploiting biology's own chemical toolbox, researchers have developed a new technique that will allow them to modify specific sequences within a DNA molecule. The approach will not only help reveal the impact of biochemical alterations to DNA, but could have far-reaching implications for DNA-based medical diagnosis and nanobiotechnology.

28 Nov 2005