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Researchers discover potential target genes to halt thyroid cancer progression

Thyroid cancer is a disease with good cure rates in most cases. In 5% of patients, however, the tumor becomes refractory to the available therapies and may spread all over the body, causing death.

19 Jan 2018

Findings reveal conventional cancer therapy as double-edged sword

Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

18 Jan 2018

Researchers identify new anti-inflammatory drug target

A new study suggests that parmodulins may provide anti-inflammatory and anti-thrombotic protection to endothelial cells, without interfering with clotting.

16 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Study finds new mechanism regulating giant protein essential for muscle and heart function

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role in the function of skeletal muscle and the heart.

12 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

IVF just as likely to result in live birth when frozen embryos are used

Women who use frozen embryos for in vitro fertilization (IVF) have the same chance of ongoing pregnancy and giving birth as those who have IVF, finds study.

11 Jan 2018

Researchers create ‘protocells’ for delivering drugs to deepest tumor regions

Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics.

11 Jan 2018

Both fresh and frozen embryos provide similar IVF success rates

For women using in vitro fertilization to have a child, using either fresh or frozen embryos have similar success rates for most women, according to an international team of researchers.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Researchers uncover powerful new model for studying hallmark of vascular disease

While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

Researchers develop new compound that inhibits growth of melanoma cells

An international team of researchers has developed a novel compound that successfully inhibits growth of melanoma cells by targeting specific epigenetic modifying proteins in these cells.

4 Jan 2018

Researchers grow hairy skin using mouse stem cells

Indiana University School of Medicine researchers have cultured the first lab-grown skin tissue complete with hair follicles.

3 Jan 2018

Supercomputers help scientists to devise cancer models for predicting individual treatment outcomes

Attempts to eradicate cancer are often compared to a "moonshot" -- the successful effort that sent the first astronauts to the moon.

3 Jan 2018

Blueberry extract can enhance effectiveness of cervical cancer treatment

According to the Centers for Disease Control and Prevention, approximately 12,000 women in the United States are diagnosed with cervical cancer each year.

29 Dec 2017

Study opens up new avenues for stopping calcific aortic valve disease

The diminutive size of our aortic valve -- just shy of a quarter -- belies its essential role in pushing oxygen-rich blood from the heart into the aorta, our body's largest vessel, and from there to all other organs. Yet for decades, researchers have focused less on damaged valves than on atherosclerosis, the gradual hardening of the blood vessels themselves.

26 Dec 2017