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Novel consortium aims to create new paradigm of cancer drug discovery

Scientists from two U.S. national laboratories, industry and academia today launched an unprecedented effort to transform the way cancer drugs are discovered by creating an open and sharable platform that integrates high-performance computing, shared biological data from public and industry sources and emerging biotechnologies to dramatically accelerate the discovery of effective cancer therapies.

27 Oct 2017

Study supports that weekend work may not be needed for most IVF/ICSI treatments

It's unclear whether there is a need to retrieve a woman's eggs on weekends, in connection with in vitro fertilization/intracytoplasmatic sperm injection (IVF/ICSI) treatment in couples wishing to conceive.

27 Oct 2017

Discovery may provide insight into how Zika virus gets transmitted from mother to fetus

Researchers at the University of California San Diego School of Medicine, with colleagues in Brazil, report that the Zika virus is transmitted from mother to fetus by infected cells that, ironically, will later develop into the brain's first and primary form of defense against invasive pathogens.

27 Oct 2017

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Very little is still known about how neurons can be generated from stem cells. Researchers at the University Medical Center of Johannes Gutenberg University Mainz have now developed a promising technique that will facilitate the differentiation of stem cells into neurons. This even enables them to accelerate the maturation process.

26 Oct 2017

Study: New histone modifications link cellular metabolism to chromatin architecture

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published in 'Nature Structural and Molecular Biology'.

26 Oct 2017

Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

A new study, conducted by researchers at MIT, suggests that a recently developed synthetic gene circuit can stimulate the immune system to kill cancer cells when it identifies indications of the cancer. The gene circuit will only stimulate a therapeutic response when it identifies two particular cancer markers.

20 Oct 2017

IGeneX launches three new tests to aid diagnosis of Borreliosis

IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis).

16 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions including Colorado State University and Fred Hutchinson Cancer Center reported results today from a glioblastoma study in which they validated a biomarker indicative of a patient's prognosis and likely response to specific therapies.

16 Oct 2017

EKF Diagnostics and Ortho Clinical Diagnostics collaborate on a new diabetic ketoacidosis assay

Ortho Clinical Diagnostics and EKF announce an agreement that allows Ortho customers to access to Beta-Hydroxybutyrate assay.

From EKF Diagnostics 12 Oct 2017

World’s only Atomo HIV Self Test receives CE Marking from European Union Notified Body

Atomo Diagnostics, a world leader in innovative point-of-care, rapid diagnostic devices, announced today that its Atomo HIV Self Test has been granted CE Marking by a European Union Notified Body.

12 Oct 2017

Research expands range in dry preservation of mammalian sperm cells

In a paper forthcoming in the November issue of the journal Theriogenology, a team of researchers from the University of North Carolina at Charlotte and the Smithsonian Conservation Biology Institute, announced the first successful drying and rehydration of domestic cat spermatozoa using a rapid microwave dehydration method.

12 Oct 2017

MAIT cells could serve as new biomarkers for early detection, prevention of type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disease that develops when the immune system attacks beta cells in the pancreas. This destructive process is often attributed to autoreactive T lymphocytes. Yet the innate immune system, our body's first line of defense, also plays an important role in this disease.

10 Oct 2017

Simple biomechanical test can help analyze tissue implant quality

The quality of the tissue-implant interface is key to the success of implant integration. High-output benchtop screening can help developers in assessing the complex interplay between biomaterials and the body to better prepare for clinical trials, highlights a review in the journal Science and Technology of Advanced Materials.

10 Oct 2017

University of Akron researcher awarded NSF grant to study bone remodeling

Osteoporosis is a disease categorized by brittle bones and increased risk of fracture. Individuals with osteoporosis, and diseases like it, have access to a number of treatments but no permanent solution.

9 Oct 2017

Penn study explains how acute viral infections can linger

Infections caused by viruses, such as respiratory syncytial virus, or RSV, measles, parainfluenza, and Ebola, are typically considered acute. These viruses cause disease quickly and live within a host for a limited time. But in some cases, the effects of the infection, and presence of the virus itself, can persist.

6 Oct 2017

in vitro News and Research

Novel consortium aims to create new paradigm of cancer drug discovery

Study supports that weekend work may not be needed for most IVF/ICSI treatments

Discovery may provide insight into how Zika virus gets transmitted from mother to fetus

JGU researchers develop new technique to facilitate differentiation of stem cells into neurons

Study: New histone modifications link cellular metabolism to chromatin architecture

Pollutant from forest and crop fires induces genetic damage in human lung cells

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

IGeneX launches three new tests to aid diagnosis of Borreliosis

Investigating new cancer therapy candidates with live-cell imaging

Scientists validate biomarker indicative of brain cancer patient's prognosis and drug response

EKF Diagnostics and Ortho Clinical Diagnostics collaborate on a new diabetic ketoacidosis assay

World’s only Atomo HIV Self Test receives CE Marking from European Union Notified Body

Research expands range in dry preservation of mammalian sperm cells

MAIT cells could serve as new biomarkers for early detection, prevention of type 1 diabetes

Simple biomechanical test can help analyze tissue implant quality

University of Akron researcher awarded NSF grant to study bone remodeling

Penn study explains how acute viral infections can linger

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

ITL Group returns to MEDICA 2017 to discuss future of diagnostic devices

Researchers discover circadian clock at work in our muscles

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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