Metabolic Disorders News and Research

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Metabolic enzyme tied to obesity and fatty liver disease

A team of researchers at the Clemson University found that Cyp2b gene, which metabolizes endo and xenobiotics, may be linked to age-onset obesity and dyslipidemia, especially in males.

11 Jul 2019

UCR biomedical professor to investigate how body's cannabis-like molecules influence obesity

More than two-thirds of adults in the United States are overweight or obese. Eating foods containing high levels of fats and sugars -- the "Western diet" -- can lead to obesity and significantly reduce life expectancy.

11 Jul 2019

Bariatric surgery should be offered to all patients who would benefit

Experts are calling for more patient's to be offered bariatric surgery as a weight loss intervention for obesity.

10 Jul 2019

A small chemical change reverses prediabetes in obese mice

A small chemical change - shifting the position of two hydrogen atoms - makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease.

5 Jul 2019

Probiotic containing common gut bacterium could halve cardiovascular disease rates

A small study has found that supplements of the gut bacterium, A. muciniphila, may cut cardiovascular disease rates in half.

3 Jul 2019

High sleep variability and short sleep duration predict blunted weight loss

This is one of the conclusions of the Predimed-Plus study, Prevention with the Mediterranean Diet, which has been published in the June issue of the International Journal of Obesity. It is the first study to examine whether the quality of sleep is related to weight loss and a reduction in adipose tissue.

28 Jun 2019

New mutation discovered in the leptin gene

The global obesity epidemic is so far-reaching it now has an overarching name: globesity. Texas Biomed Staff Scientist Raul Bastarrachea, M.D., is part of a team that discovered a new mutation in the gene that regulates the key hormone suppressing hunger called leptin.

22 Jun 2019

Food responses are governed by the gut microbiome, finds new study

A study published this week reveals that the interactions of bacteria in our gut (the gut microbiome) with the food we eat differs markedly between individuals.

13 Jun 2019

Irregular sleep patterns associated with metabolic abnormalities

A new study has found that not sticking to a regular bedtime and wakeup schedule--and getting different amounts of sleep each night--can put a person at higher risk for obesity, high cholesterol, hypertension, high blood sugar and other metabolic disorders.

6 Jun 2019

Sleep extension may help reduce cardiometabolic risk

Increasing sleep duration may help reduce cardiometabolic risk--or the risk of heart disease and metabolic disorders-- in individuals who do not get enough sleep, according to an analysis of all published studies on the topic.

6 Jun 2019

Researchers discover signaling protein that may protect parathyroid glands from hyperactivity

Overactive parathyroid glands,which control the body's blood calcium levels, can lead to kidney stones, neuropsychiatric disorders and bone abnormalities, particularly among elderly women.

29 May 2019

Epigenetic research provides new approaches to cancer combination therapies

Epigenetic processes enable cells to respond to changes in their environment by regulating the activity of their genes.

28 May 2019

Deactivating specific protein with drugs reverses inflammation, scarring of liver in NASH patients

A team of researchers led by Duke-NUS Medical School and National Heart Centre Singapore found that deactivating a specific protein - interleukin 11 - with drugs called therapeutic antibodies, reverses inflammation and scarring of the liver in patients suffering from an untreatable type of fatty liver disease called non-alcoholic steatohepatitis .

25 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

Researchers explore link between aging fat cells and Alzheimer's

Scientists want to know whether our aging fat cells are important to the onset and progression of Alzheimer's.

21 May 2019

Overweight and obese adolescents have similar increased risks of heart disorders

A study performed in Brazil by researchers from São Paulo State University suggests that overweight and obese adolescents have similar increased risks of developing heart disorders. The results of cardiovascular fitness tests with volunteers aged 10-17 were similar in both groups.

21 May 2019

Scientists decipher transcriptome of drumstick tree by RNA sequencing

Did you ever wonder why our grandmothers insisted on having a Tulsi plant in front of the house and a Moringa tree in the backyard? Each and every part of the drumstick tree has medicinal value and is a rich source of nutrients and minerals.

10 May 2019

More care is needed for patients after kidney transplantations, reports research

Patients with chronic kidney disease, and dialysis patients especially, have a significantly higher cardiovascular morbidity and mortality than healthy people. Kidney transplantation is the best renal replacement therapy available.

19 Apr 2019

Researchers identify cause of inherited metabolic disorder

A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder.

16 Apr 2019

NASA Twins Study: Extended spaceflight has small, transient effect on the gut microbiome

A year in space seems to have a small but significant, transient effect on the gut microbiome, according to a new paper on the NASA Twins Study published in the journal Science.

12 Apr 2019