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Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

A new study published in Vaccine assesses the safety and efficacy of the synthetic DNA vaccine candidate INO-4800, delivered as a single or double dose regime.

18 Jul 2021

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers.

16 Jul 2021

Messenger RNA vaccines against COVID-19 not found in breast milk

Messenger RNA vaccines against COVID-19 were not detected in human milk, according to a small study by UC San Francisco, providing early evidence that the vaccine mRNA is not transferred to the infant.

16 Jul 2021

Moderna SARS-CoV-2 vaccine highly effective against alpha and beta variants

The Moderna SARS-CoV-2 vaccine was widely distributed and had a reported efficacy in clinical trials of 94.1% against the wildtype SARS-CoV-2 following the second dose administration. Therefore, Chemaitelly et al. used this as an opportunity to measure the vaccine's efficacy against these variants as reported in a recent Nature Medicine paper, finding that the vaccine has good efficacy in all aspects.

16 Jul 2021

Study shows joint effects of perceived risk and availability on cannabis use

Combined perceptions of the risk and availability of cannabis influence the risk of cannabis use more than perceived risk and perceived availability alone, according to a new study at Columbia University Mailman School of Public Health.

16 Jul 2021

Mixing COVID vaccines generates a comparable immune response

The validity and safety of mixing first and second doses of different types are explored in a paper recently uploaded to the preprint server medRxiv* by Rose et al. (July 13th, 2021), finding that robust antibody response is induced, comparable to, and perhaps even exceed that generated by homologous dosing.

16 Jul 2021

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers in the United States have designed a modular protein subunit vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that elicited a strong immune response in macaques and prevented the animals from developing coronavirus disease 2019 (COVID-19).

15 Jul 2021

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

T cells are components of the body’s immune system. The ability of T cells to recognize diverse pathogens and mount a defense against them stems from the way proteins are spliced during their development and maturation.

15 Jul 2021

Should we be concerned about the SARS-CoV-2 Lambda variant?

As the coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), wreaks havoc across the globe, the efficacy of available vaccines is being threatened by emerging variants.

15 Jul 2021

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

Researchers in Sweden have challenged the interpretation that variable non-pharmaceutical interventions (NPIs) and “herd immunity” protection are responsible for the rise and fall of coronavirus disease 2019 (COVID-19) epidemic waves in hard-hit locations where authorities have not enforced strict NPIs.

14 Jul 2021

New OMV-based COVID-19 vaccine candidate proves effective in mice

Researchers in Italy have demonstrated the efficacy of using modified outer membrane vesicles (OMVs) as a vaccine to protect against coronavirus disease 2019 (COVID-19) in an animal model.

14 Jul 2021

Fungi that live in the gut may be equally important in health and disease

Bacteria's role in gut health has received a lot of attention in recent years. But new research led by scientists at University of Utah Health shows that fungi-;another microorganism that lives within us-;may be equally important in health and disease.

14 Jul 2021

Early life exposure to antibiotics could alter brain development

Antibiotic exposure early in life could alter human brain development in areas responsible for cognitive and emotional functions, according to a Rutgers researcher.

14 Jul 2021

Could corticosteroids increase mortality in COVID-19 patients without high oxygen supplementation?

A new paper focuses on the role of corticosteroids, in particular, as these were widely used among patients on intensive respiratory support (IRS).

14 Jul 2021

Vaccine hesitancy among young adults may stall efforts to achieve herd immunity

Vaccine skepticism among young adults may stall efforts to achieve herd immunity - a threshold in which approximately 80 percent of a population is vaccinated against the coronavirus.

14 Jul 2021

COVID-19 vaccine booster strategy against Delta variant evidence of growing inequity, says WHO

Could the COVID-19 vaccine booster dose strategy being planned in wealthyy nations underscore issues of health inequality?

14 Jul 2021

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

An inflammatory-aging clock called developed by Stanford University School of Medicine and the Buck Institute for Research on Aging can predict how strong your immune system will be in 10 years, when you'll become frail or whether you may develop cardiovascular diseases a few years down the road.

14 Jul 2021

Israeli study of breakthrough infections following full BNT-Pfizer vaccination, 40% immunocompromised

Severe forms of coronavirus disease (COVID-19) linked to high mortality rates might arise in a minority of fully-vaccinated individuals with many co-occurring medical conditions, finds a recent study by Israeli researchers published in the journal Clinical Microbiology and Infection.

13 Jul 2021

Molecular dynamic analysis of SARS-CoV-2 inhibitors

A new study reports the results of molecular dynamic simulations that were performed in an effort to identify new drugs that could be effective against SARS-CoV-2.

13 Jul 2021

EU travel pass comes under fire for leaving behind Covishield recipients

A mandatory pass for travel within the European Union during the COVID-19 pandemic has come under fire for leaving behind lower-income countries reliant on the COVAX facility for vaccinations.

13 Jul 2021

immunity News and Research

Evaluation of a synthetic DNA SARS-CoV-2 vaccine INO-4800 using a nonhuman primate model

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

Messenger RNA vaccines against COVID-19 not found in breast milk

Moderna SARS-CoV-2 vaccine highly effective against alpha and beta variants

Study shows joint effects of perceived risk and availability on cannabis use

Mixing COVID vaccines generates a comparable immune response

COVID-19 vaccine candidate that can be produced in yeast proves effective in macaques

Researchers study the role of subnuclear NSrp70 in T cell-mediated adaptive immunity

Should we be concerned about the SARS-CoV-2 Lambda variant?

“Herd immunity” not responsible for Sweden’s control of COVID-19, say researchers

New OMV-based COVID-19 vaccine candidate proves effective in mice

Fungi that live in the gut may be equally important in health and disease

Early life exposure to antibiotics could alter brain development

Could corticosteroids increase mortality in COVID-19 patients without high oxygen supplementation?

Vaccine hesitancy among young adults may stall efforts to achieve herd immunity

COVID-19 vaccine booster strategy against Delta variant evidence of growing inequity, says WHO

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

Israeli study of breakthrough infections following full BNT-Pfizer vaccination, 40% immunocompromised

Molecular dynamic analysis of SARS-CoV-2 inhibitors

EU travel pass comes under fire for leaving behind Covishield recipients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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