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COVID-19-associated blood plasma inflammatory factors do not affect blood-brain barrier, study shows

It is now well documented that the coronavirus outbreak triggered a global health crisis. In this study, researchers wanted to know whether blood-brain barrier impairment contributed to the development of neurological problems during COVID-19 progression, and to what extent.

19 Jan 2024

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles?

Study investigates the pathophysiology of post-exertional malaise in long COVID patients, revealing skeletal muscle changes, exercise capacity reduction, metabolic disturbances, and tissue alterations.

8 Jan 2024

Revolutionary self-folding nanoscale MRI agent sharpens cancer imaging

Study introduces a novel self-folding nanoscale contrast agent for MRI, enhancing tumor visualization with lower gadolinium loads and reduced risk of adverse effects.

5 Dec 2023

First-of-its-kind study reveals a new culprit in the formation of brain hemorrhages

A first-of-its-kind study led by the University of California, Irvine has revealed a new culprit in the formation of brain hemorrhages that does not involve injury to the blood vessels, as previously believed.

20 Nov 2023

Expert consensus on the classification of acute atherothrombotic myocardial infarction by stage of tissue injury severity

A document published in the Canadian Journal of Cardiology outlines the Canadian Cardiovascular Society's classification of acute MI.

1 Nov 2023

Non-invasive eye exam could be a valuable tool for early detection of cerebral small vessel disease

A research team led by the Keck School of Medicine of USC has discovered that a non-invasive eye exam may be a possible tool for screening Black Americans and other people from underdiagnosed and high-risk populations for cerebral small vessel disease, a major contributor to cognitive impairment and dementia.

6 Oct 2023

Mechanoresilient cancer cells more prone to metastasis

The ability of cancer cells to metastasize, or spread from one part of the body to another, is one of the reasons why cancer can be extremely challenging to treat.

22 Sep 2023

Researchers develop a wearable bioelectronic system for wound healing treatment delivery

Researchers presented a wearable bioelectronic system to deliver therapeutic agents associated with wound healing.

12 Sep 2023

Transparent crystal ribcage for real-time imaging of lung function

Researchers develop the ‘crystal ribcage,’ a transparent ribcage for real-time lung imaging at cellular resolution.

14 Aug 2023

Penn State researchers receive $3 million grant to develop new revascularization techniques

The ability to regenerate and pattern blood vessels, the literal lifelines extending deep into soft tissues, remains an elusive milestone in regenerative medicine.

7 Jul 2023

Non-invasive technique can help identify infants at high risk for retinopathy of prematurity

Research from Ann & Robert H. Lurie Children's Hospital of Chicago promises to spare many premature infants from undergoing invasive eye exams to detect retinopathy of prematurity (ROP), the most common cause of preventable lifelong blindness in children in the U.S.

29 Jun 2023

World's largest map of breast tissue provides an unprecedented understanding of mammary biology

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

28 Jun 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

New technique could mechanically enhance glymphatic transport in the mouse brain

Like the lymphatic system in the body, the glymphatic system in the brain clears metabolic waste and distributes nutrients and other important compounds.

16 May 2023

Team successfully treats aggressive vascular malformation in an infant's brain before birth

In a first, a team from Brigham and Women's Hospital and Boston Children's Hospital successfully treated an aggressive vascular malformation in an infant's brain before birth, avoiding potentially fatal symptoms after delivery.

5 May 2023

Researchers perform in-utero surgery to repair a potentially deadly developmental condition

For the first time, researchers performed a successful in-utero surgery to repair a potentially deadly developmental condition by treating an aggressive vascular malformation, called vein of Galen malformation, in a fetus's brain before birth, according to new research published today in Stroke, the peer-reviewed flagship journal of the American Stroke Association, a division of the American Heart Association.

5 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

Key molecular pathway for organ damage in COVID patients discovered

Even after three years since the emergence of COVID-19, much remains unknown about how it causes severe disease, including the widespread organ damage beyond just the lungs.

5 Apr 2023

Scientists find a good treatment target for pulmonary hypertension

The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood inside our lungs and oxygen to our bodies.

14 Mar 2023

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study's primary endpoint and a validated surrogate for functional improvement and reduced symptom burden.

6 Mar 2023