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Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease.

12 Sep 2022

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Prion diseases are incurable, deadly neurological disorders that can affect both humans and animals–including Creutzfeldt-Jakob Disease (CJD) in people, Bovine Spongiform Encephalopathy (also known as Mad Cow Disease) and Chronic Wasting Disease found in deer.

13 Jul 2022

Montana’s Blackfeet tribe to use dogs to sniff out disease and contaminants

Kenneth Cook used a mallet and a chisel to crack into a pig's skull in the gravel driveway outside his home on the Blackfeet Indian Reservation in northwestern Montana.

30 Jun 2022

New insights into how NANOG protein facilitates the activation of human cell pluripotency

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function.

28 Apr 2022

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9th in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues.

23 Mar 2022

The emergence of infectious diseases from the "germ’s eye view”

The study highlighted that the disruption caused by the COVID-19 pandemic has shown that human societies remain ill-prepared and susceptible to novel infectious diseases.

16 Feb 2022

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to research published today in PLOS Genetics.

11 Feb 2022

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Scientists have recently detected and analyzed viral PrDs in the S protein of SARS-CoV-2, which are the novel regulators of virion assembly.

31 Jan 2022

New technologies for early clinical diagnosis of human prion diseases

Early and accurate diagnosis of human prion diseases is a long-standing difficulty. Currently, the definitive diagnosis of human prion diseases relies on pathognomonic histological features or PrPSc detection of patients' brain tissue biopsy or autopsy samples, which is not feasible in most cases.

11 Jan 2022

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

The EU Joint Programme - Neurodegenerative Disease Research (JPND) initiative has announced a joint transnational call for multinational research on understanding the mechanisms of non-pharmacological interventions.

10 Jan 2022

New study shines light on how brain cells die in prion diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

22 Dec 2021

Researchers discover new mechanism behind the formation of membrane vesicles

Canadian and American researchers have discovered a new mechanism by which membrane vesicles are made. These self-contained nanoparticles trap proteins, RNA and other molecules from inside or outside of living cells as nutrients or regulate the numbers of cell surface hormone receptors, such as those for insulin, to control the sensitivity of cells to hormones.

10 Dec 2021

Research may provide clues to how viral infections contribute to neurodegeneration

Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the scientific journal "Nature Communications".

19 Oct 2021

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

The highest-ever resolution imaging of an infectious prion provides the first atomic-level data of how these abnormal proteins are assembled to cause fatal neurodegenerative diseases in people and animals-; and how they can be potentially targeted by new therapies.

24 Aug 2021

Prion News and Research

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Montana’s Blackfeet tribe to use dogs to sniff out disease and contaminants

New insights into how NANOG protein facilitates the activation of human cell pluripotency

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

The emergence of infectious diseases from the "germ’s eye view”

Circadian cycle controls the brain's ability to clear a protein linked to Alzheimer's disease

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

New technologies for early clinical diagnosis of human prion diseases

JPND announces call for multinational research on understanding the mechanisms of non-pharmacological interventions

New study shines light on how brain cells die in prion diseases

Researchers discover new mechanism behind the formation of membrane vesicles

Research may provide clues to how viral infections contribute to neurodegeneration

Atomic-level imaging of infectious prions reveals new therapeutic targets for untreatable diseases

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

First insights into human prion disease could help tackle neurodegenerative diseases

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

Study demonstrates the novel agonistic effect of curcumin on lipid transcription

Preventing seizures after head injury could slow or prevent the onset of dementia

Microbiology eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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