TIRF Microscopy News and Research

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TIRF is a microscopy technique that is used to image fluorescent molecules, such as green fluorescent protein (GFP) and fluorochromes, in liquids that are adjacent to a solid with a high refractive index.

Scientists describe how HIV assemble at the membrane of infected cells and are released to attack healthy cells

Although recent advances have raised hopes that a protective vaccine can be developed, acquired immunodeficiency syndrome (AIDS) remains a major public health problem. Much has been learned about HIV-1, the virus that causes the disease.

13 Nov 2009

Cells use import machinery to export their goods as well

In the bustling economy of the cell, little bubbles called vesicles serve as container ships, ferrying cargo to and from the port - the cell membrane. Some of these vesicles, called post-Golgi vesicles, export cargo made by the cell's protein factory.

9 Jul 2009

DIY high-tech microscope

A resourceful lecturer at the University of Essex has turned his hand to a spot of DIY and built a high-tech microscope that will transform the university's ability to undertake specialist medical and biological research.

3 Nov 2008

Dual-mode nanoscale imaging yields new details of cellular events

To create drugs capable of targeting malignancies, scientists must first decode exactly how a cell or a group of cells communicates with other cells and reacts to a broad spectrum of complex biomolecules surrounding it.

21 Aug 2006