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Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

The incidence of a potentially life-threatening complication of diabetes, diabetic ketoacidosis, in youth in Colorado at the time of diagnosis of type 1 diabetes increased by 55 percent between 1998 and 2012, suggesting a growing number of youth may experience delays in diagnosis and treatment, according to a study in the April 21 issue of JAMA, a theme issue on child health.

22 Apr 2015

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins.

22 Apr 2015

CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

A cellular defect that can impair the body's ability to handle high glucose levels and could point the way to a potential new treatment for diabetes has been identified by Columbia University Medical Center researchers.

8 Apr 2015

Study identifies gut immune system as new, effective target for diabetes

A commonly-used drug to treat inflammatory bowel disease, such as Crohn's disease, has been shown to lower blood sugar levels in obese mice, potentially identifying the gut immune system as a new and effective target in treating diabetes in humans.

8 Apr 2015

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease.

18 Mar 2015

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

New animal studies at Henry Ford Hospital found that sildenafil, a drug commonly used to treat erectile dysfunction, may be effective in relieving painful and potentially life-threatening nerve damage in men with long-term diabetes.

18 Mar 2015

TCC-EZ Casting System dramatically increases healing process of diabetic foot ulcers

Diabetics once facing the prospect of amputation to their lower limbs due to the effects of foot ulcers are now back on their feet thanks to a new technology.

18 Mar 2015

Obese older adults have higher rate of hospitalizations, ER admissions

Obesity is associated with substantial increases in older adults' hospitalizations, emergency room admissions and use of outpatient health care services, according to a new study of 172,866 Medicare Advantage members throughout the U.S.

9 Mar 2015

Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Obstructive sleep apnea (OSA) is prevalent in obese, pregnant Asian women with gestational diabetes, even when their diabetes is controlled by diet, a new study from Thailand finds.

9 Mar 2015

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

Sanofi announced today that the U.S. Food and Drug Administration approved Toujeo (insulin glargine [rDNA origin] injection, 300 U/mL), a once-daily long-acting basal insulin, to improve glycemic control in adults living with type 1 and type 2 diabetes. Toujeo is expected to be available in the U.S. at the beginning of Q2 2015.

26 Feb 2015

DPP-4 inhibitors effective against low blood sugar levels

DPP-4 inhibitors are a group of drugs used to treat type 2 diabetes that lower high blood sugar levels by stimulating insulin production in the body. Researchers at Lund University in Sweden have now discovered that DPP-4 inhibitors are also effective against low blood sugar levels.

23 Feb 2015

Scientists reveal genetic links to metabolic disorders

For at least 40 years, scientists who study how the body metabolizes sugar have accepted one point: there are four enzymes that kick-start the body's process of getting energy from food.

5 Feb 2015

Women’s risk factors for heart disease

Heart disease is often thought of as a health problem for men, but more and more women die of heart disease each year than men, and from any other disease including breast cancer.

4 Feb 2015

Janssen, Gilead to jointly develop darunavir-based, single-tablet regimen for HIV treatment

Janssen R&D Ireland announced today an amendment to its existing agreement with Gilead Sciences, Inc., initially established in 2011, for the development of a once daily, darunavir-based, single-tablet regimen (STR) for the treatment of people living with HIV.

29 Dec 2014

Negative health effects of severe obesity

The negative health effects of severe obesity are very well known and have been thoroughly documented, yet obesity levels in the United States continue to remain stubbornly high. Many of these repercussions are life threatening and include heart attack, stroke, and a greatly increased chance of developing cancer.

27 Dec 2014

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

Novartis announced today that the US Food and Drug Administration has approved Signifor long-acting release (LAR) (pasireotide) for injectable suspension, for intramuscular use, for the treatment of patients with acromegaly who have had an inadequate response to surgery and/or for whom surgery is not an option.

16 Dec 2014

New drug shows promise against treatment-resistant non-small cell lung cancer

A new drug that targets not only common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), but also a form of the mutation that causes resistance to treatment, has shown promising results in patients in a phase I/II clinical trial.

23 Nov 2014

Hospital bed positioning can affect outcomes of stroke patients

During the first 24 hours after a stroke, attention to detail --such as hospital bed positioning -- is critical to patient outcomes.

31 Oct 2014

Treating prediabetes patients could help prevent severe complications associated with diabetes

Doctors at three leading research institutions and the American Diabetes Association report that treating patients with prediabetes as if they had diabetes could help prevent or delay the most severe complications associated with this chronic disease, which affects about thirty million people in the United States.

25 Sep 2014

FDA grants Breakthrough Therapy designation to EYLEA Injection for treatment of diabetic retinopathy

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted EYLEA (aflibercept) Injection Breakthrough Therapy designation for the treatment of diabetic retinopathy in patients with diabetic macular edema (DME).

16 Sep 2014

High Blood Sugar News and Research

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

Study identifies gut immune system as new, effective target for diabetes

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

TCC-EZ Casting System dramatically increases healing process of diabetic foot ulcers

Obese older adults have higher rate of hospitalizations, ER admissions

Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Sanofi announces FDA approval of Toujeo insulin to improve glycemic control in people with diabetes

DPP-4 inhibitors effective against low blood sugar levels

Scientists reveal genetic links to metabolic disorders

Women’s risk factors for heart disease

Janssen, Gilead to jointly develop darunavir-based, single-tablet regimen for HIV treatment

Negative health effects of severe obesity

Novartis announces FDA approval of Signifor LAR for treatment of patients with acromegaly

New drug shows promise against treatment-resistant non-small cell lung cancer

Hospital bed positioning can affect outcomes of stroke patients

Treating prediabetes patients could help prevent severe complications associated with diabetes

FDA grants Breakthrough Therapy designation to EYLEA Injection for treatment of diabetic retinopathy

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