Critical Care News and Research

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More than 15 percent of our genes are mobilized to defend against microbial attacks

The body's overwhelming genetic defense, which has implications for the survival of patients who are severely burned or injured, was revealed in a sweeping analysis of gene activity in volunteers who were injected with a bacterial product that temporarily created flu-like symptoms.

1 Sep 2005

When it comes to inflammation, too much of a good thing can be deadly

In some severely injured patients, this normal healing process can develop into a lethal, whole-body response, including bloodstream infection (sepsis) and multiple organ failure. How and why inflammation turns from healing to harming is still mysterious, so doctors can't accurately predict how each injured patient will fare.

31 Aug 2005

Inexpensive method to assess the stability and quality of sleep

Using information hidden in the beat-to-beat changes of the heart's electrical signals, researchers at Beth Israel Deaconess Medical Center (BIDMC) have developed an inexpensive method to assess the stability and quality of sleep, which could be used to help understand the mechanisms of sleep control and diagnose sleep disorders, as well as to test the efficacy of sleep aids and other medications.

29 Aug 2005

Communication from physicians and health care teams needs to improve to meet patient's needs

Researchers report in the current issue of Mayo Clinic Proceedings that more than one-half of their study patients were unable to list their medications, diagnoses, treatment plan (names and purposes of medications) and common side effects of prescribed medications.

2 Aug 2005

Moraxella catarrhalis found to be responsible for 10 percent of exacerbations of COPD

A ubiquitous bacterial strain thought to be uninvolved in chronic obstructive pulmonary disease (COPD) in fact is responsible for 2-4 million flare-ups of the condition that occur annually in the United States, researchers from the University at Buffalo have shown.

20 Jul 2005

Many paramedics do not get enough clinical experience in insertion of emergency breathing tubes

Across the United States, many patients require insertion of emergency breathing tubes before arriving to a hospital, but emergency medicine researchers at the University of Pittsburgh School of Medicine have found that many paramedics - the highest level of prehospital providers - do not get enough clinical experience in this life-saving skill.

19 Jul 2005

PGE2 may be a target for Celebrex therapy

A product produced by lung cancer tumors fuels the cells that suppress immune function in patients and may be a target for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center.

17 Jul 2005

Australian doctors must be involved in planning medical response to possible local terror attacks

Australian Medical Association (AMA) President, Dr Mukesh Haikerwal, said this week it is vitally important that the AMA takes a key coordinating role in planning the medical response to any disasters including terror attacks on Australian soil.

14 Jul 2005

FDA panel says asthma drugs should stay on market but must carry warnings

The U.S. Food and Drug Administration (FDA) advisory panel has declared that three asthma drugs are safe enough to stay on the market, after concerns that in rare cases they raise the risk of severe asthma.

14 Jul 2005

Asbestos in rocks cause lung cancer

According to a study by a team at UC Davis Department of Public Health Sciences, everyday exposure to naturally occurring asbestos, increases the risk of developing malignant mesothelioma.

14 Jul 2005

Researchers identify six genes associated with lymphocytic bronchitis - could mean new test, treatments

Researchers at the San Francisco VA Medical Center (SFVAMC) and the University of California, San Francisco (UCSF) have identified six genes associated with lymphocytic bronchitis, which is thought to lead to obliterative bronchitis (OB), the most common cause of long-term failure of transplanted lungs.

13 Jul 2005

Mesothelioma may be caused by exposure to ultramafic rock

Everyday exposure to naturally occurring asbestos increases the risk of developing malignant mesothelioma, according to a study by UC Davis researchers.

13 Jul 2005

Giving oxygen may do more harm than good

Doctors and paramedics who give their patients oxygen - the most commonly administered "drug" in the world - may be doing more harm than good, a Queen's University researcher contends.

11 Jul 2005

Pomegranate juice may help babies resist brain injuries from low oxygen

Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St. Louis suggests.

28 Jun 2005

Modernising Care for Patients Undergoing Major Surgery

Hospitals could improve survival rates following major surgery by streamlining their critical care units, according to a new report launched recently at a London conference. As well as saving lives, hospitals could save an estimated £2 million each by implementing some of the report's key recommendations to help reduce hospital stay times.

27 Jun 2005

Protocol used to treat the first known survivor of rabies without prior vaccination published

The protocol used to treat the first known survivor of rabies without prior vaccination is published in the June 16, 2005, issue of the New England Journal of Medicine. It is hoped that this approach can be replicated, tested, and provide a guide for treating this fatal condition, especially in parts of the world where the incidence of rabies is rampant.

15 Jun 2005

Homeless persons prefer more aggressive medical care than the physicians making decisions for them

A new study published in the June issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians, reports that homeless persons are more likely than physicians to want lifesaving procedures performed on them.

13 Jun 2005

Convenient and non-invasive breath analyzer detects lung cancer

New research has discovered that a device they call an "electronic nose" can identify patients with lung cancer by detecting specific compounds in their breath.

1 Jun 2005

Nearly half of non-ventilated patients in intensive care units experience delirium

A study published today in the open access journal Critical Care reveals for the first time that nearly half of non-ventilated patients in intensive care units (ICU) experience delirium, which is also an independent predictor of longer hospital stay. It was previously though that this was only an issue for mechanically-ventilated ICU patients.

31 May 2005

Improvements in critical care decrease risk of post-injury multiple organ failure

Improvements in critical care and decreased use of blood transfusions over the course of the last decade are associated with decreases in the rate, severity and risk of death from post-injury multiple organ failure, according to a study in the May issue of Archives of Surgery.

16 May 2005

Critical Care News and Research

More than 15 percent of our genes are mobilized to defend against microbial attacks

When it comes to inflammation, too much of a good thing can be deadly

Inexpensive method to assess the stability and quality of sleep

Communication from physicians and health care teams needs to improve to meet patient's needs

Moraxella catarrhalis found to be responsible for 10 percent of exacerbations of COPD

Many paramedics do not get enough clinical experience in insertion of emergency breathing tubes

PGE2 may be a target for Celebrex therapy

Australian doctors must be involved in planning medical response to possible local terror attacks

FDA panel says asthma drugs should stay on market but must carry warnings

Asbestos in rocks cause lung cancer

Researchers identify six genes associated with lymphocytic bronchitis - could mean new test, treatments

Mesothelioma may be caused by exposure to ultramafic rock

Giving oxygen may do more harm than good

Pomegranate juice may help babies resist brain injuries from low oxygen

Modernising Care for Patients Undergoing Major Surgery

Protocol used to treat the first known survivor of rabies without prior vaccination published

Homeless persons prefer more aggressive medical care than the physicians making decisions for them

Convenient and non-invasive breath analyzer detects lung cancer

Nearly half of non-ventilated patients in intensive care units experience delirium

Improvements in critical care decrease risk of post-injury multiple organ failure

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