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Study unravels how caloric restriction provides beneficial effects to the brain

Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood.

19 Oct 2016

Episona unveils first innovative new male fertility test at ASRM 2016

Episona Inc., an epigenetics data company focused on improving outcomes in reproductive health, announced today the launch of Seed, an innovative new male fertility test, at the American Society for Reproductive Medicine Scientific Congress& Expo.

19 Oct 2016

Hormone levels in hair can predict chances of pregnancy in women undergoing IVF treatment

Levels of a hormone when measured in hair can significantly predict the likelihood of pregnancy in women undergoing in vitro fertilisation (IVF) treatment, scientists at The University of Nottingham have revealed.

18 Oct 2016

EKF Diagnostics’ novel diabetic biomarker test successfully externally verified

EKF, announces that its Glycated Serum Protein LiquiColor diabetic biomarker test has been verified for use on the Siemens Vista chemistry analyzer.

From EKF Diagnostics 18 Oct 2016

Breakthrough research links sphingolipid-mediated cell junctions and tumorigenesis

Almost all cell types exhibit some sort of polarity, which enables them to carry out specialized functions. Adherens junctions, which consist of the transmembrane protein cadherin and the intracellular components beta-catenin, alpha-catenin, and actin filaments, initiate cell-cell contacts and maintenance of cell polarity.

18 Oct 2016

NAC improves effectiveness of adoptive cell therapy for treating melanoma

A collaborative team of investigators at the Medical University of South Carolina and Loyola University have demonstrated for the first time that culturing T cells in N-acetyl cysteine (NAC) before they are infused as immunotherapy improves effectiveness and outcomes in a preclinical model of melanoma. These findings were reported in the October 15, 2016 issue of Cancer Research.

17 Oct 2016

Babies born to older women from assisted reproduction have fewer birth defects, research finds

Babies born to women aged 40 and over from assisted reproduction have fewer birth defects compared with those from women who conceive naturally at the same age, according to new research from the University of Adelaide.

17 Oct 2016

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

The National Institutes of Health National Heart, Lung and Blood Institute has awarded a $2.4 million grant over four years to Cleveland Clinic cancer researchers Jaroslaw Maciejewski, M.D., and Richard Padgett, Ph.D., to test the hypothesis that alterations in the pattern of splicing of target genes play a major role in the establishment or progression of myelodysplastic syndromes (MDS).

14 Oct 2016

IIVS releases technical training video on non-animal testing methods in laboratories

Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing, the Institute for In Vitro Sciences, Inc. has released a technical training video that describes a cell-based in vitro method for assessing phototoxicity - the potential for chemicals to cause damage after being exposed to light.

13 Oct 2016

Study on common bacterium presents new pathway to combat gastric cancers

A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study led by University of Georgia researchers.

12 Oct 2016

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Physicists at The University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within solid tumors.

12 Oct 2016

Ethosomes may be effective carrier system for transdermal delivery

Ethosomes are ethanolic nanovesicles that possess abundant amount of ethanol in its core which provides fluidity to the lipid bilayers and thus by this effect, improves the delivery of molecules into the deep skin layers.

7 Oct 2016

Japanese researchers discover causative gene for common type of hearing loss

A causative gene for a highly common type of hearing loss (sensorineural hearing loss, or SNHL) has been identified by a group of Japanese researchers, who successfully replicated the condition using a transgenic mouse.

6 Oct 2016

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

E-cigarette vapour is much less harmful to lung cells than cigarette smoke. Lab tests show that, unlike tobacco smoke, which causes oxidative stress and cell death, e-cigarette vapour does not. Oxidative stress and cell death are driving factors in the development of many smoking-related diseases such as COPD and lung cancer.

5 Oct 2016

Researchers discover how appetite is controlled and influenced by the brain

Researchers from Daegu Gyeongbuk Institute of Science and Technology in Korea have uncovered the mechanisms behind the enzyme that controls our appetite in response to low glucose availability in the brain.

5 Oct 2016

Researchers identify new way to prevent chemotherapy resistance in lung and breast cancers

Researchers at the University of Bradford have discovered a way to prevent chemotherapy resistance in lung cancer by blocking a protein found in cancer cells.

4 Oct 2016

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Engineering researchers at The University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells.

4 Oct 2016

Researchers confirm long persistence of Zika virus in semen and reveal its presence within spermatozoa

Recent work has shown that Zika virus persists in semen for up to 6 months after infection. In a correspondence published in The Lancet Infectious Diseases, the researchers, in addition to confirming its long persistence in semen (in this case for more than 130 days, i.e., over 4 months), reveal the presence of the virus even within spermatozoa.

4 Oct 2016

OECD publishes novel knowledge management tools for advancing non-animal testing methods

The Organisation for Economic Co-operation and Development has recently published the first five adverse outcome pathways (AOP), three of which have been developed by the European Commission's science and knowledge service, the Joint Research Centre.

30 Sep 2016

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Breast cancer is the most frequently diagnosed cancer among women, with estrogen-receptor-positive (ER+) being the most common type.

30 Sep 2016

in vitro News and Research

Study unravels how caloric restriction provides beneficial effects to the brain

Episona unveils first innovative new male fertility test at ASRM 2016

Hormone levels in hair can predict chances of pregnancy in women undergoing IVF treatment

EKF Diagnostics’ novel diabetic biomarker test successfully externally verified

Breakthrough research links sphingolipid-mediated cell junctions and tumorigenesis

NAC improves effectiveness of adoptive cell therapy for treating melanoma

Babies born to older women from assisted reproduction have fewer birth defects, research finds

Cleveland Clinic cancer researchers receive $2.4 million grant from NIH NHLBI

IIVS releases technical training video on non-animal testing methods in laboratories

Study on common bacterium presents new pathway to combat gastric cancers

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Ethosomes may be effective carrier system for transdermal delivery

Japanese researchers discover causative gene for common type of hearing loss

Exposure to e-cigarette vapour induces negligible or no oxidative damage to lung epithelial cells

Researchers discover how appetite is controlled and influenced by the brain

Researchers identify new way to prevent chemotherapy resistance in lung and breast cancers

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Researchers confirm long persistence of Zika virus in semen and reveal its presence within spermatozoa

OECD publishes novel knowledge management tools for advancing non-animal testing methods

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

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Why use light scattering to analyze proteins and viral vectors?

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