Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

TCF21 gene shown to be a tumor suppressor

Researchers have identified a new and unusual tumor suppressor gene that may be important in cancers of the lung and head and neck. The study shows that restoring the inactivated gene can slow the growth of tumor cells.

18 Jan 2006

Fatigue in long-term breast carcinoma survivors

Up to one third of women treated for breast cancer report fatigue symptoms up to 10 years after diagnosis, according to a new study.

9 Jan 2006

Targeted cancer therapies: Another step forward

While it is clear that the treatment of cancer has already begun to undergo a paradigm shift with the inclusion of innovative targeted therapies into current regimens, it would be wrong to assume these products will entirely replace traditional chemotherapy as the standard treatment for cancer sufferers.

22 Dec 2005

Targeted cancer therapies: Another step forward

22 Dec 2005

Imatinib mesylate (Gleevec) may not be effective at treating kidney cancer

Mayo Clinic Cancer Center investigators report that imatinib mesylate (GleevecTM), the drug used to treat patients with gastrointestinal stromal cancers (GISTs), is not likely to be effective for patients with high grade renal cell carcinoma -- the most aggressive kidney cancer.

22 Dec 2005

65% of ovarian cancer cells sideline body's defences

Ovarian cancer tumour cells use two separate mechanisms to evade the body’s defensive reaction - and in so doing also elude a newly discovered counteraction from the surrounding tissue.

15 Dec 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

Largest hepatitis-C U.S. study defines optimal therapy

Final results of the WIN-R trial,[1] the largest hepatitis C study conducted in U.S. patients, showed that weight-based REBETOL (ribavirin, USP) in combination therapy with PEG-INTRON (peginterferon alfa-2b) achieved significantly higher rates of sustained virologic response (SVR)[2] and lower rates of relapse compared to the combination therapy using a flat dose of ribavirin.

14 Nov 2005

Aspirin may prevent skin cancer

Australian scientists say that common drugs such as aspirin may hold the key to reducing the risk of developing skin cancer.

8 Nov 2005

Ospemifine may also help to prevent breast cancer

A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest.

3 Nov 2005

Capecitabine and Gemcitabine help battle pancreatic cancer

The prognosis of pancreatic cancer is poor but new therapies such as gemcitabine have contributed to improving the outcome for patients. Data presented at the 13th European Conference (ECCO) revealed that using the combination of gemcitabine and capecitabine increased overall survival in some patients.

3 Nov 2005

Cervical cancer control program increases rate of follow-up

Low-income women with abnormal Pap tests who participated in a program that combines screening and treatment in one visit had a higher rate of treatment and follow-up than women who did not participate, according to a study in the November 2 issue of JAMA: The Journal of the American Medical Association.

3 Nov 2005

Scientists find key step in a signaling pathway that helps orchestrate embryonic development

The study, reported in Nature (Oct. 13, 2005), focuses on the Hedgehog family of signaling molecules, which play a central role in directing development of the early embryo's growth and spatial plan, as well as its later organ and limb development. Defects in Hedgehog signaling are a significant cause of some birth defects and cancers.

25 Oct 2005

Measurement of telomerase activity in urine appears useful for detection of bladder cancer in men

The incidence of human bladder cancer has greatly increased over the last few decades, with more than 60,000 new cases diagnosed each year in the United States alone, and now represents the 4th most common malignancy in men and the 10th most common in women, according to background information in the article.

25 Oct 2005

Breast magnetic resonance imaging helps doctors select best treatment for early breast cancers

Breast magnetic resonance imaging enhances patient selection for accelerated, partial breast irradiation by detecting previously unsuspected, microscopic lesions within the breast, according to a study presented October 17, 2005, at the American Society for Therapeutic Radiology and Oncology's 47th Annual Meeting in Denver.

17 Oct 2005

New digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer

The study compared the radiation dose to patient's skin during transcatheter arterial embolization, a procedure that blocks the flow of a blood to a tumor. Doses were assessed for 12 patients using a new angiography unit with a digital flat-panel system and 12 using a conventional unit for angiographic imaging.

4 Oct 2005

State-of-the-art treatment program increases survival from the aggressive uterine papillary serous carcinoma

"Our study defines a standard of care for this aggressive and growing form of uterine cancer," said Schwartz, who is also assistant chief of obstetrics and gynecology at Yale-New Haven Hospital. The procedure more accurately determines the complete stage and appropriate treatment and reduces the recurrence of the cancer.

26 Sep 2005

No significant differences among different ethnic groups for breast cancer related to hormone replacement therapy

The study, published online September 16, 2005 in the International Journal of Cancer, the official journal of the International Union Against Cancer (UICC), did find that leaner women taking hormone replacement therapy had a relatively greater increase in breast cancer risks than heavier women.

26 Sep 2005

Workshop - stem cells in reproduction and in the brain

"Once we have found the factors by which body cells can be re-programmed into stem cells, then therapeutic cloning might become superfluous," said Hans R. Scholer, director of the Max Planck Institute for Molecular Biomedicine in Munster, Germany, at an international scientific symposium on stem cell research in Kobe, Japan.

10 Sep 2005

Toluidine blue dye reveals oral cancers

A team of Canadian scientists may have discovered a way to use a simple dye as a litmus test to identify abnormal areas of the mouth that may become cancers.

1 Sep 2005