Hyperlipidemia News and Research

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Hyperlipidemia, hyperlipoproteinemia or dyslipidemia is the presence of raised or abnormal levels of lipids and/or lipoproteins in the blood. Lipids (fatty molecules) are transported in a protein capsule, and the density of the lipids and type of protein determines the fate of the particle and its influence on metabolism.

New research may lead to new pharmacologic approaches to treating obesity

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.

5 Feb 2009

Seniors in Medicare's doughnut hole decrease use of meds

Beneficiaries enrolled in Medicare Part D who reached a gap in health care coverage known as the "doughnut hole" were much less likely to use prescription drugs than those with an employer-based plan, according to a University of Pittsburgh Graduate School of Public Health study.

3 Feb 2009

Stroke telemedicine assessed

Stroke telemedicine is a lifesaving practice that deserves further advancement, Mayo researchers write in the January 2009 issue of Mayo Clinic Proceedings.

19 Jan 2009

Staying active may lower health risks for large, retired athletes

The larger body size of professional football players doesn't increase risk of cardiovascular disease or atherosclerosis after they retire, according to research presented at the American Heart Association's Scientific Sessions 2008.

12 Nov 2008

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

New data from the JUPITER study demonstrated that Crestor (rosuvastatin calcium) 20 mg significantly reduced major cardiovascular (CV) events (defined in this study as the combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from CV causes) by a dramatic 44% compared to placebo (p<0.001) among men and women with elevated hsCRP but low to normal cholesterol levels.

10 Nov 2008

New hope for treating common form of inherited neuromuscular disease

Treatments that ramp up production of the tiny "motors" that power cells may have promise for treating one of the most common forms of inherited neuromuscular disease, according to a report in the September Cell Metabolism, a Cell Press publication. Neuromuscular disorders caused by defects in those mitochondrial motors affect a large number of children and adults worldwide, but today remain without treatment, the researchers said.

3 Sep 2008

Too little sleep and too much TV makes infants overweight

New research has found that infants and toddlers who sleep less than 12 hours a day are twice as likely to become overweight by age 3 than children who sleep longer.

9 Apr 2008

Less sleep, more TV leads to overweight infants and toddlers

Infants and toddlers who sleep less than 12 hours a day are twice as likely to become overweight by age 3 than children who sleep longer.

8 Apr 2008

Genetic variants of USF1 are associated with the increased risk for cardiovascular disease

Cardiovascular diseases (CVD) are major contributors to morbidity and mortality worldwide.

8 Apr 2008

Worried about your cholesterol?

You may want to schedule a few appointments with a registered dietitian, to get some sound advice about how to shape up your eating habits, according to a new national study led by University of Michigan Health System researchers.

6 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

7 Feb 2008

Disrupted genetic regulation causes common disturbance in metabolism of fat

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks.

5 Feb 2008

Drug metformin and lifestyle changes can help treat weight gain induced by antipsychotic drugs

Lifestyle intervention and the drug metformin are both effective against antipsychotic-induced weight gain, and treatment is most effective when the two therapies are combined, according to a study in the January 9/16 issue of JAMA.

9 Jan 2008

AstraZeneca submits sNDAs for SEROQUEL XR for bipolar symptoms

AstraZeneca has announced that the company has submitted two separate supplemental New Drug Applications (sNDAs) to the U.S. Food and Drug Administration (FDA) for once-daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of manic episodes associated with bipolar disorder and the treatment of depressive episodes associated with bipolar disorder.

3 Jan 2008

New investigational combination pill improves multiple cholesterol disorders

Patients treated with a new investigational combination pill showed significant improvements in cholesterol, triglycerides and other key lipids that lead to heart disease, according to results presented at the American Heart Association's Scientific Sessions.

5 Nov 2007

Risk of death following bariatric surgery

Approximately 1 percent of Pennsylvania residents who underwent bariatric surgery between 1995 and 2004 died within one year of the surgery and nearly 6 percent died within five years, according to a report in the October issue of Archives of Surgery, a theme issue on bariatric surgery.

16 Oct 2007

Surgical treatment of morbid obesity increases likelihood of patients returning to work

Obese Medicaid patients who undergo Roux-en-Y gastric bypass surgery may be more likely to return to work than obese Medicaid patients who do not undergo the surgery, according to a report in the October issue of Archives of Surgery, a theme issue on bariatric surgery.

16 Oct 2007

LifeCycle Pharma and Sciele Pharma announce FDA approval of new formulation of Fenofibrate

LifeCycle Pharma and Sciele Pharma announce FDA approval of fenofibrate in 120 mg. and 40 mg. dosage strengths. Sciele Pharma expects U.S. market launch by the end of 2007.

13 Aug 2007

Medicare Part D plans vary across U.S.

An examination of Medicare Part D plans in California and Hawaii reveals wide variations in drug formularies, but indicates that for many classes of drugs, it is possible to find at least one or more drug that is covered by nearly all Part D plans, according to a study in the June 20 issue of JAMA: The Journal of the American Medical Association

20 Jun 2007

Hyperlipidemia News and Research

Further Reading

New research may lead to new pharmacologic approaches to treating obesity

Seniors in Medicare's doughnut hole decrease use of meds

Stroke telemedicine assessed

Staying active may lower health risks for large, retired athletes

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

New hope for treating common form of inherited neuromuscular disease

Too little sleep and too much TV makes infants overweight

Less sleep, more TV leads to overweight infants and toddlers

Genetic variants of USF1 are associated with the increased risk for cardiovascular disease

Worried about your cholesterol?

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

Disrupted genetic regulation causes common disturbance in metabolism of fat

Disrupted genetic regulation causes common disturbance in metabolism of fat

Drug metformin and lifestyle changes can help treat weight gain induced by antipsychotic drugs

AstraZeneca submits sNDAs for SEROQUEL XR for bipolar symptoms

New investigational combination pill improves multiple cholesterol disorders

Risk of death following bariatric surgery

Surgical treatment of morbid obesity increases likelihood of patients returning to work

LifeCycle Pharma and Sciele Pharma announce FDA approval of new formulation of Fenofibrate

Medicare Part D plans vary across U.S.

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