Carcinogenesis News and Research

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Newly discovered ERK pathway proteins related to CagA induced disease

Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer.

25 Feb 2008

New understanding of cancer initiation

Researchers at the University of Nebraska Medical Center (UNMC) in Omaha have assisted in a significant discovery - the understanding of a common mechanism of cancer initiation - that could result in better cancer assessment, prevention and detection.

7 Feb 2008

Discovery of novel molecular pattern linked to colon cancer prognosis

An international research team has identified a link between the expression patterns of a class of molecules called microRNAs and how a patient's colon cancer may progress.

29 Jan 2008

Acanthus ilicifolius plant may combat liver cancer

Liver cancer is the fifth most common cancer in the world with a poor prognosis. About three quarters of the cases of liver cancer are found in Southeast Asia, including China, Hong Kong, Taiwan, Korea, India, and Japan.

17 Jan 2008

New biomarker for predicting liver cancer spread and survival discovered

New research has shown that a unique pattern of microRNAs, small RNA molecules that regulate gene activity, can accurately predict whether liver cancer will spread and whether liver cancer patients will have shorter or longer survival, even patients with early stage disease.

7 Jan 2008

The science of cancer health disparities in racial/ethnic minorities and the medically underserved

The latest biological, clinical and social research behind how cancer affects different racial and ethnic groups will be the focus of the first American Association for Cancer Research conference on the topic, entitled "The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved."

21 Nov 2007

GPRC5A gene found to be a tumor-suppressor for lung cancer

The GPRC5A gene, which is under-expressed in human lung cancer cells, suppresses lung tumors in mouse models and could provide a key to attacking lung cancer in humans, researchers at The University of Texas M. D. Anderson Cancer Center report in the Nov. 21 edition of The Journal of the National Cancer Institute.

14 Nov 2007

Tumor-suppressor gene for lung cancer identified

14 Nov 2007

Molecular markers predict risk for invasive breast cancer years before the tumor develops

A team of scientists from the University of California San Francisco has identified distinct molecular markers that predict whether or not a woman is likely to develop subsequent invasive cancer after initial diagnosis with a noninvasive form of early breast cancer.

13 Nov 2007

Vitamin A derivative associated with reduced growth in some lung cells

Treatment with a derivative of vitamin A called retinoic acid was associated with reduced lung cell growth in a group of former heavy smokers, according to a study published online October 30 in the Journal of the National Cancer Institute.

31 Oct 2007

Researchers find new mechanism explaining the promotional effect of H pylori on gastric cancer

The formation of a cancer is proven to be a multi-stage, multi-mechanism process by animal and human studies.

28 Oct 2007

New nanoprobe imaging station helps study the distribution of elements in cells

Scientists suspect that iron accumulation plays a role in neurodegenerative processes such as Parkinson's disease, but its distribution in neurons has never been observed because of the lack of techniques to do so. Until today.

26 Sep 2007

Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer

Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing women's susceptibility to developing the disease.

26 Sep 2007

Avocado extract stops growth of pre-cancerous cells that lead to oral cancer

Nutrients taken from avocados are able to thwart oral cancer cells, killing some and preventing pre-cancerous cells from developing into actual cancers, according to researchers at Ohio State University.

5 Sep 2007

Red wine for prostate cancer

Researchers at the University of Alabama at Birmingham (UAB) have found that nutrients in red wine may help reduce the risk of developing prostate cancer. The study involved male mice that were fed a plant compound found in red wine called resveratrol, which has shown anti-oxidant and anti-cancer properties.

3 Sep 2007

Chromatin remodeling complex connected to DNA damage control

When molecular disaster strikes, causing structural damage to DNA, players in two important pathways talk to each other to help contain the wreckage, scientists at The University of Texas M. D. Anderson Cancer Center report in the August edition of Cell.

12 Aug 2007

Screening method for pancreatic cancer in asymptomatic patients

EVANSTON, Ill. --- Optical technology developed by a Northwestern University biomedical engineer shown to be effective in the early detection of colon cancer now appears promising for detecting pancreatic cancer, the fourth most common cause of cancer deaths in the United States.

2 Aug 2007

Bio-engineered bladders a step closer to reality

Researchers at the University of York are using an understanding of the special cells that line the bladder to develop ways of restoring continence to patients with serious bladder conditions, including cancer.

31 Jul 2007

Sexual problems of long-term cancer survivors merit more attention

The first study to look at sexual function in very long-term female survivors of genital-tract cancer found that these women were pleased with the quality of their cancer care but less satisfied with the emotional support and information they received about dealing with the effects of the disease and treatment on sexuality.

27 Jul 2007

Protein IKKa protects checkpoint gene from chemical shutdown

A protein that is largely absent in one type of skin cancer protects an important gene in a cell's defense against harmful mutations from being silenced, researchers at The University of Texas M. D. Anderson Cancer Center report in the July 20 edition of Molecular Cell.

20 Jul 2007