in vivo News and Research

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Startling discovery on the development of human embryonic stem cells

In this week's Nature, researchers of the McMaster Cancer and Stem Cell Research Institute show that human embryonic stem (ES) cells can actually produce distinctive niche cells, which then release stem-cell nourishing proteins to help keep their parents ticking over.

12 Jul 2007

New genetic function involved in embryo development in organisms

Research aimed at understanding the mechanisms underlying embryo development has taken a step forward thanks to collaborative work between biologists specialized in the study of the fruit fly (Drosophila melanogaster) and scientists specialized in the design of mathematical models that simulate the functioning of biological systems.

11 Jul 2007

3-D microscopic views of tiny mouse brains available online

A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains - unveiled layer by layer - by extending the capabilities of conventional magnetic resonance imaging.

10 Jul 2007

Bio-adhesive vaginal foam

Foamix Ltd. has announced that the Company has been selected to present at the 34th Annual Meeting of the Controlled Release Society.

10 Jul 2007

Engineered blood vessels work like native tissue

Blood vessels that have been tissue-engineered from bone marrow adult stem cells may in the future serve as a patient's own source of new blood vessels following a coronary bypass or other procedures that require vessel replacement, according to new research from the University at Buffalo Department of Chemical and Biological Engineering.

9 Jul 2007

New minimally invasive method of treating cancer

A team of biomedical engineers at Virginia Tech and the University of California at Berkeley has developed a new minimally invasive method of treating cancer, and they anticipate clinical trials on individuals with prostate cancer will begin soon.

9 Jul 2007

Phosphatidylglycerol holds promise for psoriasis, age-related skin damage

The body may hold a secret to normalizing skin cell growth that is over zealous in psoriasis and non-melanoma skin cancers and too slow in aging and sun-damaged skin, researchers say.

29 Jun 2007

Researchers increase in vivo lifetime of nanoparticles

Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles.

29 Jun 2007

Polymeric nanoparticles show potential as new method for drug delivery

28 Jun 2007

SSRIs associated with lower bone density in older men and women

The class of antidepressant medications known as selective serotonin reuptake inhibitors may be associated with an increased rate of bone loss in older men and women, according to two articles in the June 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Jun 2007

New treatment slows the growth of colon and liver cancers

Leire Garcia Navarro, a researcher at the School of Pharmacy of the University of Navarra, has developed a new treatment which slows the growth of colon and liver cancers.

23 Jun 2007

Arpida receives FDA approval to initiate Phase II trial with intravenous iclaprim

Arpida Ltd. has announced that it has received approval from the US Food and Drug Administration for a Phase II trial with intravenous iclaprim in the treatment of patients with hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP) or healthcare-associated pneumonia (HCAP) suspected or confirmed to be due to Gram-positive pathogens.

23 Jun 2007

New treatment slows the growth of colon and liver cancers

A. Navarro, a researcher at the School of Pharmacy of the University of Navarra, has developed a new treatment which slows the growth of colon and liver cancers.

23 Jun 2007

Scientists show protein accelerates breast cancer progression in animal models

The study is being published in an advanced online edition of the Proceedings of the National Academy of Sciences.

23 Jun 2007

Multifunctional nanoparticle platforms for targeting and imaging cancer cells

There has been much recent interest in how nanotechnology will impact the field of medicine. Unfortunately, a number of promising nanostructured systems have turned out to be extremely toxic to humans, thus precluding their use in clinical applications and dashing hopes of an early success for the interdisciplinary field of nanobiotechnology.

21 Jun 2007

More effective treatment for malaria control during pregnancy in Africa

A review of previous studies indicates that two doses of a malaria preventive therapy during pregnancy provides substantial benefit to HIV-negative women in Africa, with more frequent dosing apparently necessary for HIV-positive women, according to an article in the June 20 issue of JAMA.

20 Jun 2007

New molecular mechanism discovered that may 'spontaneously' cause liver cancer

Adding more good news to last week's announcement that Nexavar (sorafenib) may be the first effective treatment for advanced liver cancer, researchers at the Lombardi Comprehensive Cancer Center at Georgetown University have uncovered a new molecular mechanism that may 'spontaneously' cause liver cancer.

20 Jun 2007

Researchers identify potential role for retinoic acid in autoimmune and inflammatory diseases

An important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others, was announced by researchers at the La Jolla Institute for Allergy & Immunology (LIAI).

17 Jun 2007

Breakdown of myelin may be the cause of Huntington's disease

Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease.

16 Jun 2007

In vivo imaging of siRNA delivery and silencing in tumors

Using magnetic nanoparticles labeled with dye molecules, a team of investigators at the Massachusetts General Hospital has developed a delivery vehicle capable of transporting antitumor small interfering RNA (siRNA) molecules into cells.

14 Jun 2007