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Both low-carb and low-fat diets help improve blood vessel function in overweight people

Overweight people who shed pounds, especially belly fat, can improve the function of their blood vessels no matter whether they are on a low-carb or a low-fat diet, according to a study being presented by Johns Hopkins researchers at an American Heart Association scientific meeting in San Diego on March 13 that is focused on cardiovascular disease prevention.

14 Mar 2012

FTY720 improves locomotor recovery in mice with SCI

A new study suggests that administering FTY720, an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury.

13 Mar 2012

Blood vessels that form within brain cancers predominantly not made up of cancer cells

Johns Hopkins scientists have published laboratory data refuting studies that suggest blood vessels that form within brain cancers are largely made up of cancer cells. The theory of cancer-based blood vessels calls into question the use and value of anticancer drugs that target these blood vessels, including bevacizumab (Avastin).

10 Mar 2012

Cancer-based blood vessel theory questioned

8 Mar 2012

New minimally invasive procedure can treat resistant hypertension

A radically different approach to treating high blood pressure - using a minimally invasive procedure- is being evaluated as part of a Pivotal Phase III 90-site national trial that includes The Carl H. and Edyth Lindner Center for Research and Education at The Christ Hospital.

8 Mar 2012

FDA approves Covidien's EverFlex Self-Expanding Peripheral Stent System

Covidien, a leading global provider of healthcare products, today announced that the U.S. Food and Drug Administration (FDA) has approved the EverFlex Self-Expanding Peripheral Stent System for use in the superficial femoral artery (SFA) and/or the proximal popliteal artery.

7 Mar 2012

Nitrogen balance occurs with a precise 24-hour rhythm in mammals

Researchers at Case Western Reserve University School of Medicine demonstrated that nitrogen balance, the process of utilizing amino acids and disposing of their toxic byproducts, occurs with a precise 24-hour rhythm - also known as circadian rhythm - in mammals. Disruption of this cycle has a direct impact on survival of organisms, and may predispose one to life altering diseases including diabetes and cardiovascular disease.

7 Mar 2012

Bevacizumab drug improves cardiac output in patients with HHT

In a small study that included 25 patients with hereditary hemorrhagic telangiectasia (a genetic disorder that leads to abnormalities of blood vessels) and severe liver involvement with this disease, patients who received the drug bevacizumab had improved cardiac output and a reduction in the duration and number of episodes of nose bleeds, a potentially life-threatening complication for patients with this disorder, according to a study in the March 7 issue of JAMA.

6 Mar 2012

FDA clears Covidien Solitaire FR revascularization device

Covidien, a leading global provider of healthcare products, today announced that the Solitaire FR revascularization device has been cleared by the U.S. Food and Drug Administration. The Solitaire FR device is intended to restore blood flow to the brain in patients suffering acute ischemic stroke by mechanically removing blood clots from blocked vessels.

5 Mar 2012

HDFT scan can show broken neural connections caused by TBI

A powerful new imaging technique called High Definition Fiber Tracking (HDFT) will allow doctors to clearly see for the first time neural connections broken by traumatic brain injury (TBI) and other disorders, much like X-rays show a fractured bone, according to researchers from the University of Pittsburgh in a report published online today in the Journal of Neurosurgery.

2 Mar 2012

BioInvent completes enrollment in BI-204 phase IIa study for atherosclerosis

BioInvent International AB and its collaborator Genentech, a member of the Roche Group, announced today that all patients have completed enrollment in the GLACIER study, a phase IIa study with BI-204 in patients with stable atherosclerotic vascular disease.

2 Mar 2012

SuperFAK protein decreases damage from heart attack by 50%

Researchers from the University of North Carolina at Chapel Hill reduced damage from a heart attack by 50 percent by enhancing a protective protein found in mice and humans.

2 Mar 2012

p14 ARF protein also regulates tumor-induced angiogenesis

Researchers at Winship Cancer Institute of Emory University have identified a new function for a gene that normally prevents the development of cancer.

2 Mar 2012

DRI scientists create novel oxygen-generating material

Scientists at the Diabetes Research Institute have developed a revolutionary technique to provide critical oxygen for maintaining the survival of insulin-producing cells. This is the first time that scientists have been able to successfully deliver oxygen locally to beta cells using a biomaterial.

1 Mar 2012

Cold air can trigger coronary events

People with heart disease may not be able to compensate for their bodies' higher demand for oxygen when inhaling cold air, according to Penn State researchers, making snow shoveling and other activities dangerous for some.

29 Feb 2012

Minimally invasive treatments to be showcased at SIR's 37th Annual Scientific Meeting

The Society of Interventional Radiology will feature minimally invasive scientific advances and new discoveries that may change the way dozens of diseases are treated at its 37th Annual Scientific Meeting March 24-29 at San Francisco's Moscone Center.

29 Feb 2012

EpiCept fourth quarter revenue decreases to $0.2 million

EpiCept Corporation today announced operating and financial results for the fourth quarter and full year ended December 31, 2011, and provided an update on the Company's key business initiatives.

29 Feb 2012

Viewpoints: Disabled 'disdain' a poisonous meme? Two sides on physician payments issue, letting Mich.'s community colleges train nurses

Disability advocates across the political spectrum strongly supported the 2010 health care reform. They had obvious reasons to do so. The new law provides protections for people with preexisting conditions, regulations to make sure insurers properly cover care for chronic illnesses and expanded coverage for young adults and low-income families. But more is at stake here than factual inaccuracies.

28 Feb 2012

Low levels of omega-3 in blood ‘ups’ risk of dementia and brain aging: Study

Researchers looked at 1,575 adults who averaged 67 years old and had no signs of dementia and had not had a stroke. They were given MRI brain scans and a battery of tests to measure memory and thinking abilities; they also had blood drawn to check the level of docosahexaenoic acid (DHA) or omega-3 fatty acids in their red blood cells. Those with the lowest levels of omega-3s showed signs of accelerated aging. They had lower brain volume, indicating shrinkage comparable to two additional years of aging. Compared with those with the highest blood levels of omega-3s, they scored lower on cognitive tests measuring such things as memory, problem solving, abstract thinking and multi-tasking.

28 Feb 2012

Vascular Magnetics to advance development of new drug delivery system for PAD

Vascular Magnetics, the first start-up company spun off by The Children's Hospital of Philadelphia, has raised $7 million to advance development of an innovative drug delivery system using magnetically targeted nanoparticles to treat peripheral artery disease.

28 Feb 2012