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New treatment proposed for brain metastases resistant to immunotherapy

Researchers at the Spanish National Cancer Research Centre (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict in which cases it should be used.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

Scientists unveil a 3D photoacoustic scanner that speeds up vascular imaging for real-time clinical use

Researchers have developed a rapid 3D photoacoustic tomography (PAT) scanner for high-resolution vascular imaging, enabling fast and detailed visualization of the microvasculature.

1 Oct 2024

Green spaces reduce the deadly impact of air pollution on people with type 2 diabetes

Long-term exposure to air pollution increases mortality risk in type 2 diabetes patients, but green spaces help mitigate these effects.

1 Oct 2024

Atherosclerosis progression associated with increased risk of death in asymptomatic individuals

The progression of atherosclerosis in people who have no symptoms of it is independently associated with the risk of dying from any cause, according to a new study led by researchers from Mount Sinai Fuster Heart Hospital, published September 30 in the Journal of the American College of Cardiology.

1 Oct 2024

Atherosclerosis burden and progression predict all-cause mortality

A study carried out at Mount Sinaí Fuster Heart Hospital in New York in collaboration with the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid provides important new information about atherosclerosis, a disease in which lipids (cholesterol) and other substances accumulate in plaques on the arterial wall, causing the vessels to harden and narrow, and increasing the risk of severe cardiovascular conditions.

30 Sep 2024

Revolutionary hand-held scanner enhances 3D imaging for early disease diagnosis

A new hand-held scanner developed by UCL researchers can generate highly detailed 3D photoacoustic images in just seconds, paving the way for their use in a clinical setting for the first time and offering the potential for earlier disease diagnosis.

30 Sep 2024

Epigenetic switch controls renin production in unexpected cell type

University of Virginia School of Medicine researchers have discovered how certain cells have the amazing ability to transform their function to help our bodies control our blood pressure.

26 Sep 2024

Review highlights evolving role of endovascular therapy in treating ischemic stroke

Stroke related to large vessel occlusion (LVO) is a leading cause of disability and death worldwide. Endovascular therapy (minimally invasive procedures like catheterization done inside the blood vessels) has transformed the management of these patients.

26 Sep 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

New guidelines for cardiovascular management in noncardiac surgery released

The 2024 guideline for cardiovascular management of adults undergoing noncardiac surgery reflects a decade of updates and new evidence since the guideline's last release in 2014.

24 Sep 2024

Calcium channel blockers show potential to restore cerebral blood flow in Alzheimer's disease

Targeting calcium channels in pericytes may improve blood flow in Alzheimer's disease, addressing early vascular dysfunction linked to cognitive deficits.

23 Sep 2024

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

This study identifies serum miRNA signatures as promising biomarkers for Alzheimer's, enhancing prediction of MCI conversion to AD with clinical relevance.

23 Sep 2024

Multiple myeloma drug shows efficacy in treating rare bleeding disorder

A drug approved for treating the blood cancer multiple myeloma may offer a safe and effective way to reduce the risk of severe nosebleeds from a rare but devastating bleeding disorder.

19 Sep 2024

Hypoxia's hidden role in boosting anti-cancer immunity

In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.

19 Sep 2024

Cancer drug shows promise for treating rare bleeding disorder

A clinical trial has demonstrated that the cancer drug pomalidomide is safe and effective in treating hereditary hemorrhagic telangiectasia (HHT), a rare bleeding disorder that impacts more than 1 in 5,000 people worldwide. The trial, led by Keith McCrae, M.D., of Cleveland Clinic and supported by the National Institutes of Health, was stopped early because of these successful findings, and has been published in the New England Journal of Medicine.

19 Sep 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

Study helps explain why having ApoE4 increases risk of neurodegeneration

A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer's disease—increases the risk of neurodegeneration and white matter damage.

18 Sep 2024

Study links diabetes drugs to lower risk of dementia and Parkinson's disease

A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a study published in the September 18, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

18 Sep 2024

Study links metal exposure to increased risk of atherosclerosis

Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors like smoking and diabetes, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

18 Sep 2024

Vascular News and Research

New treatment proposed for brain metastases resistant to immunotherapy

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Scientists unveil a 3D photoacoustic scanner that speeds up vascular imaging for real-time clinical use

Green spaces reduce the deadly impact of air pollution on people with type 2 diabetes

Atherosclerosis progression associated with increased risk of death in asymptomatic individuals

Atherosclerosis burden and progression predict all-cause mortality

Revolutionary hand-held scanner enhances 3D imaging for early disease diagnosis

Epigenetic switch controls renin production in unexpected cell type

Review highlights evolving role of endovascular therapy in treating ischemic stroke

Understanding the role of TIPS in improving renal function amid cirrhosis

New guidelines for cardiovascular management in noncardiac surgery released

Calcium channel blockers show potential to restore cerebral blood flow in Alzheimer's disease

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

Multiple myeloma drug shows efficacy in treating rare bleeding disorder

Hypoxia's hidden role in boosting anti-cancer immunity

Cancer drug shows promise for treating rare bleeding disorder

Leptin variations may influence brain health and dementia development

Study helps explain why having ApoE4 increases risk of neurodegeneration

Study links diabetes drugs to lower risk of dementia and Parkinson's disease

Study links metal exposure to increased risk of atherosclerosis

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