Age Related Macular Degeneration News and Research

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UH's Eye Institute receives $5M Elisabeth Severance Prentiss Foundation gift

The Elisabeth Severance Prentiss Foundation again has demonstrated its commitment to University Hospitals (UH) with a $5 million gift for the Eye Institute. The gift will honor the late Benjamin L. Millikin, MD, husband of Julia Severance and the grandfather of Prentiss Foundation trustee Elisabeth Alexander.

18 Feb 2012

WSU's novel gene-therapy for blindness receives $250,000 FFB grant

Technology to restore vision through the use of a component of green algae - developed by a Wayne State University professor and scientific director of the Ligon Research Center of Vision at the Kresge Eye Institute - has attracted additional funding for therapy development.

16 Feb 2012

Aganirsen demonstrates significant activity in two models of wet AMD, ischemic retinopathy

Gene Signal, a company focused on developing innovative drugs to manage angiogenesis based conditions, today announced the publication of data demonstrating the significant activity of aganirsen (GS-101, eye drops) in two important models of retinal neovascular disease, wet age-related macular degeneration (AMD) and ischemic retinopathy.

15 Feb 2012

Third patient dosed in Phase 1/2 SMD trial using RPE cells derived from hESCs

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today the dosing of third patient in its Phase 1/2 trial for Stargardt's macular dystrophy (SMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

13 Feb 2012

Regeneron reports total revenues of $123.0M for fourth quarter 2011

Regeneron Pharmaceuticals, Inc. announced financial and operating results for the fourth quarter and full year 2011 and provided an update on development programs.

13 Feb 2012

AFER congratulates the first Genentech AMD Fellowship recipients

ARVO Foundation for Eye Research (AFER) congratulates the first AFER/Genentech Age-related macular Degeneration Fellowship recipients - Balamurali K. Ambati, MD, PhD, and Stephen H. Tsang, MD, PhD. Each received $40,000 to support their age-related macular degeneration (AMD) research and will be honored at the 2012 ARVO Annual Meeting on Sunday, May 6, in Fort Lauderdale, Fla.

4 Feb 2012

Experts comment on successful stem cell therapy for blindness

According to a new study published in The Lancet, privately funded and led by UCLA and Advanced Cell Technology researchers, two women suffering a progressive form of blindness have shown improved vision.

24 Jan 2012

VisionCare closes expansion of Series E financing

VisionCare Ophthalmic Technologies, Inc., a developer of advanced visual prosthetic devices for the treatment of end-stage age-related macular degeneration (AMD), today announced the closing of expansion of the Series E financing, with Agate Medical Investments leading the expansion round. Agate's Managing General Partner, Chanan Schneider, will join the VisionCare team as a board observer.

23 Jan 2012

Study shows 50% reduction in blindness and severe visual loss in Denmark

Age-related macular degeneration (AMD) is the most frequent cause of blindness in the Western World. A report from the University of Copenhagen and Glostrup Hospital in Denmark published today shows the number of new cases of blindness and severe visual loss in Denmark has been halved during the last ten years.

20 Jan 2012

Hawaii surgeons successfully implant FDA-approved eye telescope for AMD

A team of surgeons from Hawaii, Dr. Michael Bennett of Retina Institute of Hawaii and Dr. Michael McMann of McMann Institute, has successfully implanted the FDA-approved eye telescope, a first in Hawaii, at one of the leading medical centers in Honolulu.

19 Jan 2012

Vitamin D could prevent age related eye degeneration: Study

A new study showed that increased vitamin D intake can help to prevent age-related diseases, in particular loss of vision and blindness.

18 Jan 2012

Vitamin D supplements can fight against age-related macular degeneration

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have found that vitamin D reduces the effects of ageing in mouse eyes and improves the vision of older mice significantly. The researchers hope that this might mean that vitamin D supplements could provide a simple and effective way to combat age-related eye diseases, such as macular degeneration (AMD), in people.

17 Jan 2012

ForSight VISION4 to receive first milestone payment for Lucentis drug delivery device

Genentech, a member of the Roche Group, today announced it will make its first milestone payment to ForSight VISION4, Inc. as part of an exclusive license agreement to develop the company's investigational drug delivery device, designed to provide sustained delivery of Lucentis (ranibizumab).

13 Jan 2012

Grapes offer dramatic protection against age-related macular degeneration

Can eating grapes slow or help prevent the onset of age-related macular degeneration (AMD), a debilitating condition affecting millions of elderly people worldwide? Results from a new study published in Free Radical Biology and Medicine suggest this might be the case. The antioxidant actions of grapes are believed to be responsible for these protective effects.

12 Jan 2012

Ocular drug delivery: DSM awarded membership in PANOPTES EU Funded Consortium

DSM, a global leader in biomedical materials sciences, today announced that it is contributing proprietary knowledge in the preparation of tailored amino acid-based polymers and offering use of processing facilities that will produce an innovative step change in the sustained delivery of drug molecules. The PANOPTES consortium’s goal is to research and develop novel drug delivery technology for the posterior eye segment. This partnership further validates the innovative properties of DSM’s polyesteramide (PEA) biomaterials as a superior drug delivery technology.

12 Jan 2012

Visual rehabilitation to continue to increase in near future

Visual rehabilitation will continue to increase in importance in the near future, particularly because the number of older patients is rising. Susanne Trauzettel-Klosinski summarizes the present state of knowledge in the current issue of the Deutsches Ärzteblatt International.

12 Jan 2012

Clearside Biomedical receives $4M venture capital investment

Technology developed by researchers at the Georgia Institute of Technology and Emory University for delivering drugs and other therapeutics to specific locations in the eye provides the foundation for a startup company that has received a $4 million venture capital investment.

6 Jan 2012

Dendrimers offers a new way to treat age-related macular degeneration, retinitis pigmentosa

Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A study by investigators at Mayo Clinic, Wayne State University and Johns Hopkins Medicine shows that steroids attached to the dendrimers target the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and preserving vision.

14 Dec 2011

Potential nanoparticle treatment for macular degeneration and retinitis pigmentosa

Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A collaborative research study among investigators at Wayne State University, the Mayo Clinic and Johns Hopkins Medicine shows that steroids attached to the dendrimers targeted the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and preserving vision.

14 Dec 2011

Bayer, Regeneron commence EYLEA Phase 3 clinical trial for wet AMD in China

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare today announced that they have initiated a Phase 3 clinical trial evaluating the efficacy and safety of EYLEA (aflibercept) Injection in the neovascular form of age-related macular degeneration (wet AMD) in China.

28 Nov 2011