Metabolic Disorders News and Research

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Protein complex structure that plays an important role in regulating circadian rhythm identified

Structural biologists have made important progress towards better understanding the functioning of the circadian clock. The circadian or inner clock coordinates the sleep-wake rhythm and many other body processes that regulate, for example, metabolism, blood pressure, and the immune system.

31 May 2014

Study examines how food additive MSG contributes to obesity and liver disease

The commonly used food additive monosodium glutamate (MSG) has been linked to obesity and disorders associated with the metabolic syndrome including progressive liver disease.

28 May 2014

Study identifies role of additive monosodium glutamate in obesity and liver disease

The commonly used food additive monosodium glutamate (MSG) has been linked to obesity and disorders associated with the metabolic syndrome including progressive liver disease.

28 May 2014

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Researchers at the University of Maryland School of Medicine have identified a mutation in a fat-storage gene that appears to increase the risk for type 2 diabetes and other metabolic disorders, according to a study published online today in the New England Journal of Medicine.

23 May 2014

Study examines predictors and effects of testosterone therapy

Three new studies examining the predictors, effects and durability of testosterone therapy on men will be presented to reporters at the 109th Annual Scientific Meeting of the American Urological Association (AUA) during a special press conference in the Orange County Convention Center, Orlando, FL on Sunday, May 18 at 2:00 p.m. ET.

19 May 2014

Covidien opens new facility in Turkey to expand training and research capabilities

Further expanding its training and research capabilities in emerging markets, Covidien plc (NYSE: COV), has officially opened its Covidien Center of Innovation Turkey (CCI Turkey).

7 May 2014

IKKβ links vascular inflammation to obesity and atherosclerosis development

A study in The Journal of Experimental Medicine shows that IκB kinase β (IKKβ) functions in smooth muscle cells to regulate vascular inflammatory responses and atherosclerosis development.

7 May 2014

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Second Genome announced today that it has entered into an agreement with Pfizer Inc. to conduct extensive microbiome research in a large observational study aimed at gaining new insights into obesity and metabolic disease.

2 May 2014

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Virginia Tech chemical engineer Chang Lu and his colleagues have used a National Science Foundation grant to develop a technique to detect subcellular location of a protein.

26 Apr 2014

Sleep and metabolic disorders: an interview with Professor Bernd Schultes, eSwiss Medical and Surgical Centre, St Gallen, Switzerland

Metabolic disorders are alterations in metabolic processes that can cause harm to a subject. The most common disorders affect the glucose and lipid metabolism causing diabetes and dyslipidemia. Another common disorder is obesity that affects many distinct metabolic processes.

23 Apr 2014

European scientists set up new therapeutic approaches to tackle gene defects

On 15th April is the 1st International Pompe Disease Day, a campaign to raise awareness of this rare but severe gene defect. Pompe Disease is only one of more than 40 metabolic disorders that mainly affect children under the age of 10, often with devastating consequences.

15 Apr 2014

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI, and other institutions have discovered that the activating hotspot L205R mutation in PRKACA gene was closely associated with adrenocortical tumors (ACTs), and the relationship of recurrently mutated DOT1L and CLASP2 with ACTs' other subtypes.

7 Apr 2014

New research shows obesity is linked to our ability to digest carbohydrates

New research indicates that obesity in the general population may be genetically linked to how our bodies digest carbohydrates.

1 Apr 2014

Whole-genome sequencing in newborns could help detect, manage wide array of disorders

Should whole-genome sequencing be used in the public-health programs that screen newborns for rare conditions?

29 Mar 2014

Sufficient sleep can prevent and reverse metabolic disorders

Evidence increasingly suggests that insufficient or disturbed sleep is associated with metabolic disorders such as type 2 diabetes and obesity, and addressing poor quality sleep should be a target for the prevention – and even treatment – of these disorders, say the authors of a Review, published in The Lancet Diabetes & Endocrinology journal.

26 Mar 2014

High-protein meal and exercise recipe for calorie-burning in some women

New research shows that for some women, a high-protein meal followed by 30 minutes of moderate exercise is an effective way of burning calories, especially when compared to exercising on an empty stomach.

24 Mar 2014

New tool pinpoints genetic sources of disease

Many diseases are the result of either variations in the genome or reversible chemical changes to DNA, known as the epigenome. New data obtained by Johns Hopkins scientists show a connection between genetic variants and epigenetic information.

20 Mar 2014

New data shows curative effects of GFT505 in NASH associated with metabolic disorders

GENFIT, a biopharmaceutical company at the forefront of drug discovery and development, focusing on the early diagnosis and preventive treatment of cardiometabolic and associated disorders, today announces new data from Professor Isabelle Leclercq of Université Catholique de Louvain (Belgium) demonstrating the curative effects of GFT505 in an experimental model of NASH associated with metabolic disorders.

20 Mar 2014

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

We've all heard about circadian rhythm, the roughly 24-hour oscillations of biological processes that occur in many living organisms. Yet for all its influence in many aspects of our lives - from sleep to immunity and, particularly, metabolism - relatively little is understood about the mammalian circadian rhythm and the interlocking processes that comprise this complex biological clock.

30 Jan 2014

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.

30 Jan 2014

Metabolic Disorders News and Research

Protein complex structure that plays an important role in regulating circadian rhythm identified

Study examines how food additive MSG contributes to obesity and liver disease

Study identifies role of additive monosodium glutamate in obesity and liver disease

Researchers identify mutation in fat-storage gene that appears to increase risk for type 2 diabetes

Study examines predictors and effects of testosterone therapy

Covidien opens new facility in Turkey to expand training and research capabilities

IKKβ links vascular inflammation to obesity and atherosclerosis development

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Virginia Tech scientist receives grant to develop technique to detect subcellular location of protein

Sleep and metabolic disorders: an interview with Professor Bernd Schultes, eSwiss Medical and Surgical Centre, St Gallen, Switzerland

European scientists set up new therapeutic approaches to tackle gene defects

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

New research shows obesity is linked to our ability to digest carbohydrates

Whole-genome sequencing in newborns could help detect, manage wide array of disorders

Sufficient sleep can prevent and reverse metabolic disorders

High-protein meal and exercise recipe for calorie-burning in some women

New tool pinpoints genetic sources of disease

New data shows curative effects of GFT505 in NASH associated with metabolic disorders

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

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