Positron Emission Tomography News and Research

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Solid-dominant lung cancer histology no barrier to segmentectomy

Complete resection with segmentectomy is as effective as lobectomy for patients with solid-dominant clinical stage IA lung adenocarcinoma, Japanese study findings suggest.

31 Mar 2014

PET eliminates approximately 50% of unnecessary surgeries in lung cancer patients

New quantitative data suggests that 30 percent of the surgeries performed for non-small cell lung cancer patients in a community-wide clinical study were deemed unnecessary.

27 Mar 2014

Study lays groundwork for PET imaging studies on human Menkes disease

Scientists at the RIKEN Center for Life Science Technologies have used PET imaging to visualize the distribution in the body of copper, which is deregulated in Menkes disease, a genetic disorder, using a mouse model. This study lays the groundwork for PET imaging studies on human Menkes disease patients to identify new therapy options.

26 Mar 2014

Imaging cancer in children using MRI: an interview with Dr. Heike E. Daldrup-Link, Stanford University School of Medicine

There have been a number of scientific publications recently that suggest that the radiation exposure from imaging tests can induce secondary cancers later in life.

21 Mar 2014

Plaque in brain could guide treatment decisions for patients at risk for Alzheimer's

Brain imaging using radioactive dye can detect early evidence of Alzheimer's disease that may predict future cognitive decline among adults with mild or no cognitive impairment, according to a 36-month follow-up study led by Duke Medicine.

11 Mar 2014

3D mammography now available at Lenox Hill Radiology

Lenox Hill Radiology, a wholly owned subsidiary of RadNet, Inc., a national leader in providing high-quality, cost-effective diagnostic imaging services through a network of owned and operated outpatient imaging centers, announces that 3D mammography, the latest innovation in breast cancer screening, is now available at its 79th Street location on the Upper West Side.

10 Mar 2014

AAA gets orphan drug designation status for radiopharmaceutical, Gallium-68 DOTATATE

Advanced Accelerator Applications (AAA), a fast growing international player in Molecular Nuclear Medicine (MNM), announced today that they have received orphan drug designation status for their radiopharmaceutical, Gallium-68 DOTATATE.

4 Mar 2014

New uses of imaging technologies could help scientists uncover brain's mysteries

Combining two imagine technologies, such as MRI for structure and MEG for activity, could provide a new understanding of our how our brain works.

4 Mar 2014

UCLA scientists developed experimental treatment that eradicates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center have developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects. The drug works by blocking two important metabolic pathways that the leukemia cells need to grow and spread.

25 Feb 2014

Johns Hopkins selects MILabs VECTor+ system to enhance molecular imaging capabilities

MILabs is pleased to announce that the Johns Hopkins University School of Medicine will install the recently launched MILabs VECTor+ system to expand and further enhance its contributions to translational molecular imaging.

25 Feb 2014

New radiation-free MRI test effectively diagnoses cancer in children

A new type of whole-body magnetic resonance imaging test could be an alternative to standard positron emission tomography/computed tomography imaging for assessing cancer in children and young adults, but without exposure to radiation that has been shown to increase the risk of secondary cancers in later life.

20 Feb 2014

Omeros doses first patient in second Phase 2 clinical trial of OMS824

Omeros Corporation today announced dosing of the first patient in a second Phase 2 clinical trial of OMS824, the company's phosphodiesterase 10 (PDE10) inhibitor being developed for the treatment of schizophrenia, Huntington's disease (HD) and other cognitive disorders. The Phase 2 trial will evaluate the tolerability, safety, pharmacokinetics and performance on a battery of tests in patients with symptomatic HD.

19 Feb 2014

Study shows increased brain reactivity may facilitate memorisation of dreams

Some people recall a dream every morning, whereas others rarely recall one. A team led by Perrine Ruby, an Inserm Research Fellow at the Lyon Neuroscience Research Center (Inserm/CNRS/Universit- Claude Bernard Lyon 1), has studied the brain activity of these two types of dreamers in order to understand the differences between them.

17 Feb 2014

Omeros announces additional positive data from OMS824 Phase 1 program

Omeros Corporation today announced additional positive data from its Phase 1 program for OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program. This clinical trial evaluated the extent to which OMS824 binds to PDE10, an enzyme expressed in the region of the brain that has been linked to a wide range of diseases that affect cognition. In the latest cohort enrolled in this trial, OMS824 achieved a high of approximately 70‑percent engagement at PDE10 without evidence of extrapyramidal symptoms (EPS).

11 Feb 2014

Omeros announces positive results from Phase 2a trial of OMS824 in patients with schizophrenia

Omeros Corporation today announced positive results from a Phase 2a clinical trial of OMS824, the company's phosphodiesterase 10 (PDE10) inhibitor, in which the drug was well tolerated and demonstrated comparable systemic pharmacokinetics when administered alone and concomitantly with approved antipsychotic agents in patients with schizophrenia. OMS824 selectively inhibits PDE10, an enzyme expressed in areas of the brain linked to a wide range of diseases that affect cognition, including schizophrenia and Huntington's disease.

29 Jan 2014

Increased inflammation following infection impairs brain's ability to form spatial memories

Increased inflammation following an infection impairs the brain's ability to form spatial memories - according to new research. The impairment results from a decrease in glucose metabolism in the brain's memory centre, disrupting the neural circuits involved in learning and memory.

25 Jan 2014

Gene therapy edges closer for Parkinson’s disease

Lentiviral vector-based gene therapy is well tolerated and may improve motor function in patients with Parkinson’s disease, shows an open-label study published in The Lancet.

20 Jan 2014

Research highlights potential of newly developed radiopharmaceuticals for imaging melanoma metastases

With low survival rates for patients with metastasized melanoma, accurate staging and effective treatments are critical to extending life. New research published in the Journal of Nuclear Medicine highlights the potential of newly developed radiopharmaceuticals with benzamide for the imaging of metastases and as a targeted systemic therapy.

8 Jan 2014

PET imaging of brain reveals ketamine may act as antidepressant by regulating serotonin activity

Ketamine is a potent anesthetic employed in human and veterinary medicine, and sometimes used illegally as a recreational drug. The drug is also a promising candidate for the fast treatment of depression in patients who do not respond to other medications.

7 Jan 2014

ADC values and diffusion weighted imaging can be used to detect early cerebral infarction

Supratentorial cerebral infarction can cause functional inhibition of remote regions such as the cerebellum, which may be relevant to diaschisis. This phenomenon is often analyzed using positron emission tomography and single photon emission CT. However, these methods are expensive and radioactive.

6 Jan 2014