Metabolic Disorders News and Research

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Covidien officially opens first training and education center in Mumbai, India

Further developing its capabilities in a key emerging market, Covidien has officially opened its first training and education center in India. The Covidien Center of Innovation India, located in Mumbai, offers clinicians training on advanced procedures and techniques using leading equipment and technology.

23 Jan 2014

New research shows that as we age, the thermogenic activity of brown fat gets reduced

As most people resolve themselves to lose weight this New Year, here's why it seems to get easier and easier to pack on unwanted pounds: New research published in the January 2014 issue of The FASEB Journal, shows that as we age, the thermogenic activity of brown fat is reduced. Brown fat is a "good" fat located in the backs of our necks that helps burn "bad" white fat around our bellies. Additionally, the researchers also discovered a possible metabolic on/off switch that could reactivate brown fat.

2 Jan 2014

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

A high-fat diet affects the molecular mechanism controlling the internal body clock that regulates metabolic functions in the liver, UC Irvine scientists have found. Disruption of these circadian rhythms may contribute to metabolic distress ailments, such as diabetes, obesity and high blood pressure.

20 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

AstraZeneca and Bristol-Myers Squibb Company (NYSE:BMY) today announced the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) recommends the investigational medicine metreleptin for the treatment of pediatric and adult patients with generalized lipodystrophy (LD).

12 Dec 2013

New guidelines developed to manage heart failure in children with undiagnosed heart disease

12 Dec 2013

Study defines HRV reference values for children

Measurement of heart rate variability (HRV) is a useful method when assessing the role of the nervous system for heart function. Standard reference values for heart rate variability in adults have existed for a long time already, but similar values have not been available for children until now.

26 Nov 2013

Study suggests potential new treatment for seizures

A study out today in the journal Nature Medicine suggests a potential new treatment for the seizures that often plague children with genetic metabolic disorders and individuals undergoing liver failure. The discovery hinges on a new understanding of the complex molecular chain reaction that occurs when the brain is exposed to too much ammonia.

17 Nov 2013

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Three grants totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice. The awards are from the National Institutes of Health.

26 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Gender warns of bipolar I disorder risks

Researchers have confirmed several features that differ between men and women with bipolar disorder, which may impact on the course and treatment of the condition.

11 Sep 2013

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Weill Cornell Medical College announced today that it has received a $100 million gift from longtime benefactors Joan and Sanford I. Weill and the Weill Family Foundation to launch the Medical College's $300 million Driving Discoveries, Changing Lives campaign dedicated to using the most advanced scientific approaches to rapidly translate research breakthroughs into innovative treatments and therapies for patients.

10 Sep 2013

Parasites could be potential key to treating autoimmune diseases

There is a new weapon in the fight against autoimmune diseases such as Type 1 diabetes, rheumatoid arthritis, Crohn's disease and lupus, the common trait of which is an immune system that attacks its own organs and tissues.

10 Sep 2013

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers at the University of Alberta announced today that they have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine.

6 Sep 2013

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Metabolically healthy women have the same cardiovascular disease risk regardless of their BMI, according to research presented at the ESC Congress today by Dr S-ren Sk-tt Andersen and Dr Michelle Schmiegelow from Denmark.

2 Sep 2013

Increased caffeine intake may reduce fatty liver in people with NAFLD

Surprise! Your morning cup of tea or coffee may be doing more than just perking you up before work. An international team of researchers led by Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine suggest that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease (NAFLD).

17 Aug 2013

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

Deciphering the body's complex molecular pathways that lead to disease when they malfunction is highly challenging. Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes. In the study published by Molecular Cell, the scientists uncovered how a protein called p62 has a cascade affect in regulating cell growth in response to the presence of nutrients such as amino acids and glucose. Disrupting this chain may offer a new approach to treating disease.

2 Aug 2013

Metabolic Disorders News and Research

Covidien officially opens first training and education center in Mumbai, India

New research shows that as we age, the thermogenic activity of brown fat gets reduced

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

New guidelines to manage heart failure in children

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

New guidelines developed to manage heart failure in children with undiagnosed heart disease

Study defines HRV reference values for children

Study suggests potential new treatment for seizures

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Gender warns of bipolar I disorder risks

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Parasites could be potential key to treating autoimmune diseases

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Being overweight but metabolically healthy is not linked with increased risk of heart attack

Increased caffeine intake may reduce fatty liver in people with NAFLD

Researchers now have more complete picture of mTORC1 pathway that can lead to cancer, diabetes

HHS Inspector General raises concerns about Medicare policy on observation care

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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