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Scientists grow cells that line blood vessels from human iPSCs

In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels-called vascular endothelial cells-from human induced pluripotent stem cells (iPSCs), revealing new details about how these cells function.

23 Aug 2013

Structured exercise can improve heart function in patients with kidney disease

A structured exercise and lifestyle program can improve fitness, body composition, and heart function in patients with kidney disease, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

23 Aug 2013

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings could lead to better treatments to protect the kidney health of patients with the disease.

23 Aug 2013

Noninvasive urine test can accurately monitor risk of kidney rejection

Levels of a protein in the urine of kidney transplant recipients can distinguish those at low risk of developing kidney injury from those at high risk, a study suggests. The results also suggest that low levels of this protein, called CXCL9, can rule out rejection as a cause of kidney injury.

23 Aug 2013

Ireland’s Health Research Board awards €1.2M to UL researchers

University of Limerick researchers have been awarded over €1.2 million funding by Ireland’s Health Research Board. The funding will support health research focused on; primary care reform in Ireland; avoidance of adverse outcomes in vascular surgery; dealing with the progression of chronic kidney disease and enhancing physical activity for multiple sclerosis patients.

22 Aug 2013

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Two oral targeted drugs approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, according to results of a large international clinical trial led by researchers at Dana-Farber Cancer Institute.

22 Aug 2013

University of Adelaide wins $2.24M to establish new national Center of Research Excellence

The University of Adelaide has won US$2.24 million to establish a new national Center of Research Excellence, in partnership with the South Australian Health and Medical Research Institute (SAHMRI), the National Aboriginal Community Controlled Health Organization (NACCHO) and the University of Wollongong.

22 Aug 2013

Hypertension researcher receives Distinguished Scientist title from AHA

Kenneth Bernstein, MD, a Cedars-Sinai pathologist and scientific researcher known for expanding the understanding of a collection of proteins important in controlling blood pressure as well as heart and renal diseases, has been named a 2013 Distinguished Scientist by the American Heart Association.

21 Aug 2013

High levels of urinary albumin-to-creatinine ratio linked with greater risk of CHD in black individuals

In a large national study, higher levels of the urinary albumin-to-creatinine ratio was associated with greater risk of incident but not recurrent coronary heart disease in black individuals when compared with white individuals, according to a study in the August 21 issue of JAMA.

21 Aug 2013

Full-time workers more likely to get kidney transplants

People in end-stage kidney failure in need of a kidney transplant are much less likely to be placed on a waiting list for a new kidney or to actually receive a new kidney once on the list if they are unemployed or work part time, according to new collaborative research from the University of New Hampshire.

20 Aug 2013

Arrays of nanoscale sensors detect flaws in drugs and help improve production

MIT chemical engineers have discovered that arrays of billions of nanoscale sensors have unique properties that could help pharmaceutical companies produce drugs - especially those based on antibodies - more safely and efficiently.

17 Aug 2013

Scientists have made breakthrough in understanding cancer-promoting action of herbal products

A team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Taiwan's Chang Gung Memorial Hospital, LinKou, have made a breakthrough in understanding the cancer-promoting action of Aristolochic Acid (AA), a natural product of Aristolochia plants traditionally used in some Asian herbal remedies for weight loss and slimming.

14 Aug 2013

Scientist receives grant to examine protein trigger involved in cell function regulation in breast cancer

The New Jersey Commission on Cancer Research (NJCCR) has awarded Janice Thomas, PhD, a post-doctoral fellow in the X.F. Steven Zheng laboratory at Rutgers Cancer Institute of New Jersey a two-year $100,000 grant (#DFHS13PPCO32) to further examine the impact of a protein 'trigger' involved in the regulation of cell function in breast cancer.

13 Aug 2013

Healthy diet, moderate alcohol may be associated with decreased risk of CKD in diabetes patients

Eating a healthy diet and drinking a moderate amount of alcohol may be associated with decreased risk or progression of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

13 Aug 2013

Research roundup: Use of high-deductible plans limits some E.R. visits; older folks not as sick as they used to be

One-third of US workers now have high-deductible health plans, and those numbers are expected to grow in 2014 as implementation of the Affordable Care Act continues. There is concern that high-deductible health plans might cause enrollees of low socioeconomic status to forgo emergency care as a result of burdensome out-of-pocket costs.

12 Aug 2013

Risk for childhood cancer moderately increased among adolescents with major birth defects

A multistate study led by researchers at the University of Utah has revealed that the risk for childhood cancer is moderately increased among children and young adolescents with certain types of major birth defects.

12 Aug 2013

Person with type 2 diabetes may spend nearly $85,500 to treat the disease

A person with type 2 diabetes may spend an average of nearly $85,500 to treat the disease and its complications over his or her lifetime, reports a new study in the American Journal of Preventive Medicine.

9 Aug 2013

Teplizumab to block type 1 diabetes proves strikingly effective in phase 2 clinical trial

An experimental drug designed to block the advance of type 1 diabetes in its earliest stages has proven strikingly effective over two years in about half of the patients who participated in the phase 2 clinical trial.

8 Aug 2013

Single antibiotic treatment safe and effective for children with invasive bloodstream infections

Children with invasive bloodstream infections treated with a single antibiotic are just as likely to overcome their infections as those who get two-drug therapy, but at half the risk of drug-induced kidney damage, according to results of a Johns Hopkins Children’s Center study.

6 Aug 2013

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

A team of scientists, led by Napoleone Ferrara, MD, has shown for the first time that a signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy.

6 Aug 2013

Kidney News and Research

Scientists grow cells that line blood vessels from human iPSCs

Structured exercise can improve heart function in patients with kidney disease

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Noninvasive urine test can accurately monitor risk of kidney rejection

Ireland’s Health Research Board awards €1.2M to UL researchers

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

University of Adelaide wins $2.24M to establish new national Center of Research Excellence

Hypertension researcher receives Distinguished Scientist title from AHA

High levels of urinary albumin-to-creatinine ratio linked with greater risk of CHD in black individuals

Full-time workers more likely to get kidney transplants

Arrays of nanoscale sensors detect flaws in drugs and help improve production

Scientists have made breakthrough in understanding cancer-promoting action of herbal products

Scientist receives grant to examine protein trigger involved in cell function regulation in breast cancer

Healthy diet, moderate alcohol may be associated with decreased risk of CKD in diabetes patients

Research roundup: Use of high-deductible plans limits some E.R. visits; older folks not as sick as they used to be

Risk for childhood cancer moderately increased among adolescents with major birth defects

Person with type 2 diabetes may spend nearly $85,500 to treat the disease

Teplizumab to block type 1 diabetes proves strikingly effective in phase 2 clinical trial

Single antibiotic treatment safe and effective for children with invasive bloodstream infections

Signaling protein involved in inflammation also promotes tumor resistance to anti-angiogenic therapy

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