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Mayo Clinic researchers find earliest sign of nerve change due to diabetes

Mayo Clinic researchers have found that subtle change in nerve conduction is the first reliable sign of nerve complications from diabetes and that this change can be measured long before other symptoms or signs of nerve damage develop.

3 Oct 2005

Weight control protein may yield new approaches for treating obesity and type 2 diabetes

The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said.

16 Aug 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

Over-supply of blood sugar could be a major cause of erectile dysfunction in diabetic men

Researchers have found that one particular simple sugar, present in increased levels in diabetics, interferes with the chain of events needed to achieve and maintain erection and can lead to permanent penile impairment over time.

9 Aug 2005

Older-style antidepressants, as well as anticonvulsant drugs, can help ease the disabling pain caused by nerve tissue damage

For many years antidepressants, which are believed to work by dampening pain signals, have been the first-line drugs for neuropathic pain. "It is usual to start with an antidepressant like amitriptyline, and if this fails then try an anticonvulsant," says Phil Wiffen, a researcher at Churchill Hospital in Oxford, England. "The results of these meta-analyses suggest this is probably still the best approach to take."

19 Jul 2005

Metabolic syndrome prevented by a fit heart

According to a new study, a person's cardiorespiratory fitness is a strong predictor of their risk of developing metabolic syndrome.

12 Jul 2005

Major study says for diabetics with high blood pressure diuretics are the best option

A major new study has found that for people with type 2 diabetes and high blood pressure, cheaper diuretic medications may be the most cost-effective option in reducing hypertension.

29 Jun 2005

Study reveals benefits of using insulin earlier

Results of an all-Canadian study announced June 13 at an international diabetes congress demonstrate that patients with type 2 diabetes can safely achieve target blood sugar (glycemic) levels faster and more frequently when insulin glargine (a basal, long-acting insulin) is added to therapy, versus using oral agents alone.

14 Jun 2005

Patients with metabolic syndrome and moderate calcium levels in the coronary arteries have greater chance of blocked arteries

Conditions such as abdominal obesity, high blood pressure, abnormal cholesterol levels and high blood sugar are problematic enough for people all on their own.

26 May 2005

A drug that controls blood pressure and reduces heart risk also appears to protect against diabetes

In new results from the VALUE trial that pitted the drug valsartan against another blood pressure drug, amlodipine, the patients taking valsartan were found to have a 23 percent lower risk of developing diabetes during the four or more years of the study.

18 May 2005

Scientists use transcription factors to increase insulin production in diabetic mice

A group of Japanese scientists has used gene therapy to deliver three insulin transcription factors, MafA, PDX-1, and NeuroD, to the livers of diabetic mice. As a result, the mice experienced an increase in insulin gene expression and insulin production, raising the possibility that this could eventually be used to treat diabetes.

13 Apr 2005

Prozac, Xenical and Meridia may help type 2 diabetes patients lose weight

Three commonly used drugs - Prozac, Xenical and Meridia - may help type 2 diabetes patients lose small amounts of weight, although long-term benefits are not clear, a new review of 22 studies suggests.

20 Feb 2005

Link between diabetes and obesity

Scientists at Washington University School of Medicine in St. Louis used genetically modified mice to uncover a potentially important link between diabetes and obesity.

15 Feb 2005

Scientists show knocking out key signals will cause diabetes

Using a revolutionary technique to turn off chemical signals inside the cell, scientists at Joslin Diabetes Center have discovered that the different metabolic abnormalities present in type 2 diabetes can be caused by knocking out two key signals in liver cells.

11 Feb 2005

Scientists identify fat gene

UCLA/VA scientists have identified a new gene that controls how the body produces and uses fat. Called lipin, the gene may provide a new target for therapies to control obesity, diabetes and other weight-related disorders. The first issue of the new journal Cell Metabolism publishes the findings in its January 2005 edition.

19 Jan 2005

Weight, fitness and lifestyle are important factors contributing to metabolic syndrome

The metabolic syndrome, a group of several abnormalities, including obesity and high blood pressure, in one individual was identified in 10.4 percent of 36-year-old study participants, according to an article in the January 10 issue of Archives of Internal Medicine.

10 Jan 2005

Sticking to one diet plan key to losing weight

A comparison of four popular diet plans finds that the key to losing weight may not be which diet plan a person picks, but sticking with the plan that is chosen, according to a study in the January 5 issue of JAMA.

5 Jan 2005

Veterans Affairs patients with diabetes are better cared for than managed care patients

Researchers have found that Veterans Affairs patients with diabetes are more likely to receive recommended tests and have better outcomes than managed care patients.

17 Aug 2004

Mexican-Americans have a far higher chance of suffering a stroke than non-Hispanic whites

And, according to a second study published today by the same team, the difference doesn't appear to be related to Mexican-Americans' higher incidence of diabetes, which had been thought to raise their risk of a certain type of stroke.

9 Aug 2004

Obesity in mothers is one of the most decisive factors contributing to the appearance of congenital malformations in their children

A study of more than 2000 children of women with gestational diabetes (the diabetes that some women get during pregnancy) has revealed that obesity in mothers is one of the most decisive factors contributing to the appearance of congenital malformations in their children, even more so than the seriousness of the diabetes.

16 Jul 2004