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Novel way in which the brain size of developing mammals may be regulated

Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development.

14 Jul 2005

Viagra's non-blood pressure effect successfully mimics vasopressin action

Normally your kidneys filter about 50 gallons of blood a day, remove such waste as salts and minerals, and concentrate it into urine. When you exercise or don't take in water, your blood "thickens" and instead of removing water, the kidney reverses the process, pulls in water from the body that would normally go into the urine, and puts it into the blood, thus maintaining water balance.

29 Jun 2005

Uncomplicated twin pregnancies might be more risky than previously thought

As mothers get older and assisted conception becomes more common, the incidence of multiple births - primarily of nonidentical siblings, but also of identical ones - has dramatically increased.

28 Jun 2005

Study causes big shift in how we think about p53 gene

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate mutations, which ultimately may lead to cancer.

27 Jun 2005

High-tech infertility treatment for men most common therapy to help couples conceive

According to recently released figures, a high tech treatment for male infertility has become the most common therapy in Europe to help couples conceive.

23 Jun 2005

Scientists identify inhibitors of the anthrax toxin

A collaborative team of scientists led by The Burnham Institute's Maurizio Pellecchia, Ph.D., has identified inhibitors of the anthrax toxin, termed lethal factor ("LF") that could be developed into an emergency treatment for exposure to inhalation anthrax.

21 Jun 2005

Eggs from embryonic stem cells could benefit sterile women

Monash University researchers have developed a process that causes embryonic stem (ES) cells to develop into ovarian structures containing eggs.

21 Jun 2005

New cardiovascular drug derived from Dan Shen (Saliva miltiorrhiza)

Through a large number of clinical trials over the past 3 years, researchers from the CAS Shanghai Institute of Materia Medica (SIMM) have developed a new cardiovascular drug with a definite effective component extracted from Dan Shen (Saliva miltiorrhiza), a medicinal herb widely used in China.

21 Jun 2005

Researchers use novel cocktail of cells to coax muscle tissue to develop its own vascular network

For years, a major obstacle has dashed the hopes of creating "replacement parts" for the human body: the lack of an internal, nourishing blood system in engineered tissues. Without it, thicker tissues can't thrive, which has confined tissue engineering's practical application to thin skin, which can recruit blood vessels from underlying tissue.

20 Jun 2005

Australian researchers develop process that causes embryonic stem cells to develop into ovarian structures containing eggs

The researchers believe the process could in future be used to develop eggs for sterile women that contain the women's own genetic material.

20 Jun 2005

Stem cells grown in lab mirror normal developmental steps

Johns Hopkins scientists have developed a way to study the earliest steps of human blood development using human embryonic stem cells grown in a lab dish instead of the embryos themselves.

20 Jun 2005

Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

The Global Alliance for TB Drug Development (TB Alliance), a non-profit public-private partnership developing affordable, new drug regimens for tuberculosis, today announced the start of Phase I clinical trials for the lead TB drug in its pipeline, PA-824. The trials begin this month.

14 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Omega-3 combined with propofol may lead to new drugs to treat breast cancer

Omega-3, the fatty acid found in oily fish, could be combined with a commonly used anesthetic to develop drugs to treat breast cancer, according to research published in the journal Breast Cancer Research.

8 Jun 2005

HIV protease inhibitors block programmed cell death in vivo

The immunodeficiency that arises in HIV may be due to excessive programmed cell death of immune CD4 T cells.

3 Jun 2005

Triple approach is promising against cancer cells

A trimodal treatment strategy combining chemotherapy, radiation therapy, and a protein kinase inhibitor is much more effective against cancer cells than any combination of only two treatment methods.

1 Jun 2005

Baby boy is first successful birth in Canada from frozen eggs

McGill University Health Center (MUHC) in Montreal yesterday announced the first successful birth in Canada resulting from frozen eggs. A healthy baby boy, weighing 3740 grams was born on April 29 to a 26-year-old mother who had suffered from infertility for two years.

31 May 2005

A new technique might allow women diagnosed with cancer the opportunity to have children when chemotherapy and radiation treatments rob them of their fertility

Freezing eggs is one thing; thawing them safely so they can lead to pregnancy is the challenge. In the past, efforts to freeze a woman's eggs, or oocytes, have not worked well because the cells are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized.

29 May 2005

U.S. House of Representatives approve two bills on stem-cell research

Two new bills related to stem-cell research have been approved by the U.S. House of Representatives one promoting non-destructive methods and the other supporting research resulting in the death of unborn children.

26 May 2005

The National Infertility Association joins infertility groups to Support Stem Cell Research Enhancement Act

The National Infertility Association joins with the American Society for Reproductive Medicine (ASRM) and the American Fertility Association in support of the Stem Cell Research Enhancement Act, HR 810.

23 May 2005