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Shp2 protein plays a critical role in obesity

A team of researchers led by The Burnham Institute's Gen-Sheng Feng, Ph.D. has discovered that a protein called Shp2 plays a critical role in obesity.

11 Nov 2004

Cranberry juice may help prevent gum disease

New research presented at a recent symposium suggests that cranberry juice may help prevent certain oral health problems, including diseases of the gums and teeth.

9 Nov 2004

Protease inhibitors used to treat HIV-1 infection may also be effective for treatment or prevention of malaria

The study found protease inhibitors inhibited the growth of P. falciparum, the malaria parasite that causes most disease. These findings may also expose a previously unexplored vulnerability in the parasite that could lead to a new class of anti-malarial drug.

8 Nov 2004

Discovery of a number of potent and selective small molecule inhibitors of the hepatitis C (HCV) NS3/4 protease

InterMune announced today the presentation of preclinical data on the discovery and characterization of a number of potent and selective small molecule inhibitors of the hepatitis C (HCV) NS3/4 protease.

1 Nov 2004

Controversial theory about how diabetes causes extensive tissue damage

A controversial theory about how diabetes causes extensive tissue damage will appear in the November issue of Diabetes. At stake in the heated debate over the theory are researchers' efforts to find new ways to reduce loss of vision, kidney failure, heart damage and other side effects of diabetes.

29 Oct 2004

New insights into hormone therapy show when estrogen best aids brain

New hormone therapy studies demonstrate estrogen's ability to directly stimulate neurons, repair damaged neurons, and stimulate support cells—most of which can alleviate some of the cognitive decline associated with menopause.

28 Oct 2004

Potential new protein marker for prognosis of breast and ovarian cancer

The researchers matched tumor samples to outcomes in about 100 patients diagnosed with either breast or ovarian cancer and found that a low level of Rab25 protein on a patient's cancer sample was associated with a better clinical outcome in both cancer types.

24 Oct 2004

Recommendations made for new research to settle questions on in vitro fertilization (IVF)

Twenty-five years after the birth of the first baby conceived through in vitro fertilization (IVF), there remain many unanswered questions about the health and well-being of babies born following IVF.

20 Oct 2004

Race may play a role in the success of their infertility treatment

Research presented today at the 60th Annual Meeting of the American Society for Reproductive Medicine (ASRM) indicated that a patient’s race may play a role in the success of their infertility treatment.

18 Oct 2004

Cranberries for the treatment of herpes

Alpine cranberries have significant biological activity that can help to combat herpes virus type II (HSV-2) infection, one of the most common viral infections in humans, writes Emma Dorey in Chemistry & Industry.

18 Oct 2004

Signaling pathway could be a valuable target for future drug therapies against systemic lupus erythematosus

Medical investigators at the Hospital for Special Surgery have identified an important new signaling pathway they believe could be a valuable target for scientists to aim at with future drug therapies that might one day reverse diseases such as systemic lupus erythematosus, according to a recent article published in “Nature Immunology.”

11 Oct 2004

Moderate exercise in mice after they were infected with influenza protects them from dying

University of Illinois researchers report that four consecutive days of moderate exercise in mice after they were infected with influenza protects them from dying, compared with mice that didn’t exercise.

5 Oct 2004

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New research has opened up the prospect that gossypol – a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive – could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.

30 Sep 2004

Research confirms benefits of commonly used traditional remedies for a range of illnesses

Research presented to the British Pharmaceutical Conference today, confirms the benefits of commonly used traditional remedies for a range of illnesses, including cancer, offering a scientific justification for their use.

29 Sep 2004

New methods for the growth and development of human pancreatic beta islets

Vitro Diagnostics has announced the development of new methods for the growth and development of human pancreatic beta islets (Islets of Langerhans) and the filing of a new patent application with the United States Patent and Trademark Office.

27 Sep 2004

32-year-old woman has given birth to a healthy baby 7 years after banking her ovarian tissue before starting chemotherapy

Although she became infertile as a result of the chemotherapy, re-implantation of her ovarian tissue re-started ovulation 5 months later; she became pregnant 11 months after re-transplantation by natural fertilization. Details of the procedure appear in a research article published online by THE LANCET.

23 Sep 2004

Slimming agents could pose major health risk

Commonly used nutritional supplements and body-building agents for elite athletes could pose an increased risk of cancer according to a study undertaken at the University of Sydney.

16 Sep 2004

Transthyretin discovery may halt progression of Alzheimer's

In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer's disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease.

10 Sep 2004

Sinovac completes dosing in phase 1 human clinical testing of SARS vaccine

Sinovac Biotech Ltd. has announced that all 36 subjects of the Phase I human clinical trial for its inactivated SARS vaccine have now been vaccinated with two doses of either SARS vaccine or placebo.

7 Sep 2004

Chemotherapy experts refute ASCO recommendations on use of drug sensitivity and resistance assays

A group of leading chemotherapy experts assembled as the Clinical Oncologists for Individualized Therapy (COFIT) refute the findings of the American Society of Clinical Oncology (ASCO) technology assessment panel regarding the use of chemotherapy sensitivity and resistance assays (CSRAs).

1 Sep 2004