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Semaglutide enhances cognitive abilities and reduces Alzheimer’s pathology in mice and human brain models

Researchers find that Semaglutide improves cognitive function and reduces amyloid and tau pathology in Alzheimer's disease models, while restoring oxytocin levels in both mice and human brain organoids.

14 Oct 2024

New vial size could save Medicare millions on Alzheimer's drug

Medicare could save up to 74% of the money lost from discarded Alzheimer's drug lecanemab by the simple introduction of a new vial size that would reduce the amount of unused medication that is thrown away, new research suggests.

14 Oct 2024

Chronic stress disrupts gut microbiota, promoting colorectal cancer growth

Cutting-edge research has uncovered how chronic stress disrupts the balance of gut microbiota to speed up the progression of colorectal cancer (CRC), opening new avenues for CRC prevention and treatment.

13 Oct 2024

Oral health strategies for healthy aging: A call to action

Research explores the connection between aging populations and oral health, proposing an integrated model to address health challenges in older adults, with a focus on policy changes in the UK.

10 Oct 2024

Bilingualism enhances brain connectivity and efficiency

Neuroplasticity is the brain's ability to build connections within itself, adapting to the surrounding environment.

10 Oct 2024

Rise in human life expectancy may be slowing down

Research indicates that without major advances in aging, radical life extension is improbable, necessitating reforms in retirement planning and life insurance.

10 Oct 2024

Study explores link between muscle strength and mental health in older adults

The Granada Biosanitary Research Institute (ibs.GRANADA) and the University of Granada, in collaboration with the Biomedical Research Institute of Malaga and Platform in Nanomedicine (IBIMA Plataforma BIONAND), have carried out a study that analyses the relationship between muscle strength and mental health in cognitively healthy older adults.

10 Oct 2024

Older men’s connections often wither when they’re on their own

At age 66, South Carolina physician Paul Rousseau decided to retire after tending for decades to the suffering of people who were seriously ill or dying. It was a difficult and emotionally fraught transition.

10 Oct 2024

Montana looks to fast-track Medicaid access for older applicants

Montana is looking to fast-track Medicaid access for older adults who need help to stay in their homes or towns.

10 Oct 2024

The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

COVID-19 testing and variants more prevalent in minority communities

More than four years after the COVID-19 pandemic caused the world to come to a standstill, lessons in pandemic response are still being learned. What we know: the global pandemic disproportionately affected racial and ethnic minority groups across the U.S., with Black and Hispanic individuals being three to four times more likely to die from COVID compared to white individuals.

10 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

Exploring the role of gut microbes in the aging process

Aging is a universal and complex process affecting all organisms, characterized by several genetic hallmarks such as telomere attrition, genomic instability, and epigenetic changes.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

Maintaining healthy weight may support brain vascular health in aging population

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 18 on September 18, 2024, entitled, "Determinants of cerebral blood flow and arterial transit time in healthy older adults."

8 Oct 2024

Deciphering the Mysteries of the Human Microbiome

The Microsetta Initiative studies human microbiomes, analyzing diverse data to reveal links between microbes, diet, and health for improved public health.

8 Oct 2024

Common breast cancer therapies may speed up aging, study shows

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center has revealed that common breast cancer treatments, including chemotherapy, radiation, and surgery, may accelerate the biological aging process in breast cancer survivors.

8 Oct 2024

New UCL hub to advance cancer detection with imaging tech

UCL will lead a £17 million surgical imaging hub to improve cancer detection and take part in a £12 million collaboration to help solve age and disability-related mobility issues, in a major funding award from the UKRI Engineering and Physical Sciences Research Council (EPSRC).

8 Oct 2024

Environmental factors significantly impact gene expression through epigenetic modifications

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment. The review article "Epigenetics and Environmental Health" provides an in-depth analysis of how epigenetic modifications can influence the onset and progression of various diseases, particularly cancer and cardiovascular diseases.

8 Oct 2024

Study suggests humans are approaching a biological limit to life

We've seen dramatic increases in life expectancy over the 19th and 20th centuries, thanks to healthier diets, medical advances and many other quality-of-life improvements.

8 Oct 2024