Therapeutics News and Research

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Findings could alter ways in which doctors use platelets to treat traumatic injuries

A new finding could lead to novel treatments to reduce bleeding in trauma and severe infections.

2 Sep 2013

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

University of Notre Dame researchers, as part of a collaborative effort, have identified a protein that potentially could be a target for drugs that would help people recover faster from jet lag and better adjust their circadian rhythms during rotational shift work.

31 Aug 2013

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

Schizophrenia is one of the most devastating neurological conditions, with only 30 percent of sufferers ever experiencing full recovery. While current medications can control most psychotic symptoms, their side effects can leave individuals so severely impaired that the disease ranks among the top ten causes of disability in developed countries.

31 Aug 2013

Texas A&M University biologist receives federal grant to study Clostridium difficile

A Texas A&M University biologist has received a federal grant to study the fecal samples of hundreds of people to better understand the gut bacteria Clostridium difficile - the cause of some 14,000 deaths a year in America - and to help lay the basic science foundation to develop drugs to combat its deadly results.

30 Aug 2013

Jia Shen receives 2013 Jess Hay Chancellor's Graduate Student Research Fellowship

Jia Shen, a student at The University of Texas Graduate School of Biomedical Sciences at Houston, is a recipient of a 2013 Jess Hay Chancellor's Graduate Student Research Fellowship. This award is given to two students per year across the entire University of Texas System, which is comprised of nine universities and six health institutions.

29 Aug 2013

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

Institut Curie's Emmanuel Barillot receives Agilent Thought Leader Award

Agilent Technologies Inc. today announced that Dr. Emmanuel Barillot, director of Bioinformatics and Systems IT at the Institut Curie in Paris, has received an Agilent Thought Leader Award in recognition of his pioneering development of user-friendly, Web-based bioinformatics tools for systems toxicology.

28 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

USF professor studies ethics of RCT and efficacy in outcomes of new treatments

University of South Florida Distinguished Professor Benjamin Djulbegovic, MD, PhD, has studied the ethics of randomized clinical trials and their effectiveness in evaluating the outcomes of new treatments for decades.

28 Aug 2013

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Companion diagnostics is critical in helping to pave the way for personalized medicine, in which the treatment is adapted and precisely tailored to the patient.

From Siemens Healthineers 27 Aug 2013

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

When Francis Crick and James Watson discovered the double helical structure of deoxyribonucleic acid (DNA) in 1953, it began a genetic revolution to map, study, and sequence the building blocks of living organisms.

27 Aug 2013

UAB study points to protein pathway that could lead to new treatments for diabetes

The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham study published online today in the journal Nature Medicine.

27 Aug 2013

Sangamo BioSciences signs definitive agreement to buy Ceregene

Sangamo BioSciences, Inc. announced that it signed a definitive agreement to acquire Ceregene, Inc., a privately held biotechnology company focused on developing adeno-associated virus gene therapies.

26 Aug 2013

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

...

26 Aug 2013

FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Ceptaris Therapeutics, Inc., a privately held, specialty pharmaceutical company, announced today that the U.S. Food and Drug Administration has granted marketing approval for the orphan drug VALCHLOR (mechlorethamine) gel for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have received prior skin-directed therapy.

26 Aug 2013

Immune Pharmaceuticals announces completion of merger with EpiCept Corporation

Immune Pharmaceuticals Inc. announced today the completion of the merger of Immune Pharmaceuticals Ltd. and EpiCept Corporation.

26 Aug 2013

Researchers discover additional cystic fibrosis-causing mutations

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF.

26 Aug 2013

Glutathione peroxidase activity protects against symptoms of Huntington's disease

Leicester geneticists have discovered a potential defence against Huntington's disease - a fatal neurodegenerative disorder which currently has no cure.

26 Aug 2013

New Pharmacological Drug Target Identified In The Brain

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22 Aug 2013

Cellectricon to discuss phenotypic assay designs for chronic pain research in webinar

Cellectricon, a leading provider of advanced cell-based screening technologies and services, invites researchers to join the webinar entitled “Phenotypic Screening Strategies for Chronic Pain Research”, taking place on 5 September, 11:00 am to 12:00pm EDT.

From Cellectricon 21 Aug 2013

Therapeutics News and Research

Findings could alter ways in which doctors use platelets to treat traumatic injuries

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

Researchers develop model that completes bridge between cellular and human studies of schizophrenia

Texas A&M University biologist receives federal grant to study Clostridium difficile

Jia Shen receives 2013 Jess Hay Chancellor's Graduate Student Research Fellowship

Researchers develop new opioid drug for chronic pain

Institut Curie's Emmanuel Barillot receives Agilent Thought Leader Award

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

USF professor studies ethics of RCT and efficacy in outcomes of new treatments

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Scientists prove 50-year-old hypothesis of RNA 'higher-order' structure

UAB study points to protein pathway that could lead to new treatments for diabetes

Sangamo BioSciences signs definitive agreement to buy Ceregene

BARDA Awards Novan $7.8M To Develop Thermal Burns Treatment

FDA grants marketing approval for VALCHLOR gel for treatment of early stage CTCL

Immune Pharmaceuticals announces completion of merger with EpiCept Corporation

Researchers discover additional cystic fibrosis-causing mutations

Glutathione peroxidase activity protects against symptoms of Huntington's disease

New Pharmacological Drug Target Identified In The Brain

Cellectricon to discuss phenotypic assay designs for chronic pain research in webinar

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