Metabolic Disorders News and Research

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GI Dynamics to present additional results of mechanisms of actions clinical study

GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced that additional results from a previously reported clinical study regarding mechanisms of action will be presented on Saturday, August 29, 2009 by Manoel Galvao Neto, M.D., scientific coordinator, Gastro Obeso Center, Sao Paulo, Brazil and lead investigator for the study, at the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) 14th World Congress in Paris, France.

27 Aug 2009

Sabril (vigabatrin) Oral Solution receives approval from FDA

Sabril (vigabatrin) Oral Solution has been approved by the U.S. Food and Drug Administration to treat infantile spasms in children ages 1 month to 2 years. Sabril is the first drug in the United States approved to treat the disorder, characterized by a severe type of seizure that usually appears in the first year of life, typically between ages 4 months and 8 months.

26 Aug 2009

Santaris Pharma to discover and develop new RNA-based medicines for treating rare genetic disorders

Santaris Pharma A/S, a privately-held biopharmaceutical company focused on developing RNA-based drugs targeted to disease-related mRNAs and microRNAs, today announced a multi-year worldwide strategic alliance with Shire plc to discover and develop new RNA-based medicines to treat rare genetic disorders.

24 Aug 2009

Ron Demuth of ChemDiv announces extension of collaboration with Lilly

ChemDiv, Inc. announced the expansion of its drug discovery collaboration with Eli Lilly through 2010. Under the terms of the agreement, the partners will identify and develop leads for an additional therapeutic target using ChemDiv's small molecule resources (the industry's largest commercial collection) and Discovery outSource™ drug discovery and development platforms.

21 Aug 2009

High-fat diet affects physical and memory abilities of rats after 9 days

Rats fed a high-fat diet show a stark reduction in their physical endurance and a decline in their cognitive ability after just nine days, a study by Oxford University researchers has shown.

11 Aug 2009

Fainting may point to more serious, underlying cardiovascular condition

For those who suffer from fainting spells, the mysterious episodes can be quite scary. Far too often, fainting is chalked up to stress or other mental health issues. However, medical experts at Rush University Medical Center say that reoccurring fainting spells, also known as syncope, could be an important symptom that can point to a more serious, underlying cardiovascular condition.

10 Aug 2009

Two studies on polycystic ovarian syndrome shed light on its causes and its effect on brothers of women with the condition

Researchers have found evidence that chronic disease in either a mother or father can create unfavourable conditions in the womb that are associated with the development of polycystic ovarian syndrome (PCOS) in daughters. In another study, researchers found that brothers of women with PCOS and insulin resistance are themselves at greater risk of developing insulin resistance or diabetes, suggesting that factors associated with the condition can be passed down to sons as well as daughters.

30 Jun 2009

Seniors need more sun!

Spending more time in the sunshine could help older people to reduce their risk of developing heart disease and diabetes.

11 May 2009

ADA releases official stance on obesity, reproduction and pregnancy outcomes

Diet and nutrition counseling for virtually all overweight and obese women of childbearing age can reduce health risks associated with excess weight for mothers and children alike, according to a newly released position paper from the American Dietetic Association and the American Society of Nutrition.

30 Apr 2009

Is metabolic character different between men and women with gallstone disease?

There are a cluster of metabolic syndrome, that include obesity, high level of fasting plasma glucose, hypertriglyceridemia and hypertension, which is closely associated with the increased morbidity and mortality caused by several of the most common diseases including diabetes, hypertension, cardiovascular diseases, cancer and gallstone disease.

20 Apr 2009

Research finds active brown fat in adult humans

Researchers at the Joslin Diabetes Center have demonstrated that adult humans still have a type of "good" fat previously believed to be present only in babies and children.

9 Apr 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

2 Apr 2009

Research reveals new options for people with phenylketonuria

For people with the genetic condition known as phenylketonuria (PKU), diet is a constant struggle.

30 Mar 2009

Metabolism and aging linked to circadian rhythm

All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism.

20 Mar 2009

Compound is key coordinator of clock and metabolism

Our circadian clock, or biological timing system, governs our daily cycles of feeding, activity and sleep.

20 Mar 2009

Metabolic and neurological disorders may share common risk factors

Metabolic disorders such as obesity and diabetes appear to share risk factors with and may influence the development of Alzheimer's disease and other forms of dementia, according to several reports published in the March issue of Archives of Neurology.

10 Mar 2009