RNA Sequencing News and Research

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RNA-seq analysis reveals key factors in intervertebral disc degeneration

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD).

15 Dec 2023

Waseda researchers unravel secrets of building better brain organoids with blood vessels

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids’ development.

15 Dec 2023

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

14 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

New study unlocks hope for immunotherapy in metastatic prostate cancer

Immunotherapy has been disappointing as a prostate cancer treatment, but a new Columbia study suggests that the powerful treatments have potential when the disease starts to spread.

12 Dec 2023

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial cells, is the most common form of pancreatic cancer, with a very high mortality rate.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

Targeting Alzheimer's with cell-specific genetics

Developing treatments for Alzheimer's disease (AD) is difficult because complex underlying mechanisms drive different types of cells that may contribute to the disorder.

5 Dec 2023

Study reveals how maternal diabetes affects birth defects at the single-cell level

The mechanisms by which maternal diabetes mellitus contributes to congenital abnormalities in the fetus.

4 Dec 2023

Study shows how aging affects communication between skin cells

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes."

30 Nov 2023

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

28 Nov 2023

RNA Sequencing News and Research

RNA-seq analysis reveals key factors in intervertebral disc degeneration

Waseda researchers unravel secrets of building better brain organoids with blood vessels

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

New study unlocks hope for immunotherapy in metastatic prostate cancer

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

Study identifies targetable fusion RNAs in breast cancer

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Targeting Alzheimer's with cell-specific genetics

Study reveals how maternal diabetes affects birth defects at the single-cell level

Study shows how aging affects communication between skin cells

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Novel urine-based prognostic model promises to transform bladder cancer treatment

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

Novel tool can help with analysis of single cell data

Senolytics show promise in combating brain aging and COVID-19 neuropathology

RNA-based molecular subtypes can help predict response to chemotherapy in muscle-invasive bladder cancer

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Sequencing & Genomics: Elevating Science and Healthcare eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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