Depressive Disorder News and Research

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CeNeRx BioPharma starts human trials of RIMA antidepressant

CeNeRx BioPharma, Inc. has announced the initiation of human clinical trials of Tyrima, CeNeRx's new drug candidate with a triple mechanism of action for the treatment of depression and anxiety.

30 Jan 2007

Link between insomnia and depression in children

According to a study published in the journal SLEEP, sleep-disturbed children are more severely depressed and have more depressive symptoms and comorbid anxiety disorders compared with children without sleep disturbance.

2 Jan 2007

FDA announces tentative approval of generic Zoloft

Lupin Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted tentative approval for the Company's Abbreviated New Drug Application (ANDA) for Sertraline Hydrochloride Tablets, 25mg, 50mg and 100mg.

2 Jan 2007

SSRIs associated with severe violence in a small number of individuals

Use of one class of antidepressant drugs, the SSRIs (selective serotonin reuptake inhibitors), may be associated with severe violence in a small number of individuals say the authors of paper published in PLoS Medicine.

12 Sep 2006

Bipolar disorder costs twice as much in lost productivity as major depressive disorder

Bipolar disorder costs twice as much in lost productivity as major depressive disorder, a study funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) has found. Each U.S. worker with bipolar disorder averaged 65.5 lost workdays in a year, compared to 27.2 for major depression.

4 Sep 2006

FDA approves generic version of Effexor (venlafaxine)

The U.S. Food and Drug Administration has approved the first generic version of Effexor (venlafaxine), an important step in the agency's effort to increase the availability of lower-cost generic medications.

9 Aug 2006

Mylan granted U.S. patent for transdermal product

Mylan Laboratories has announced that U.S. Patent No. 7,070,808 was issued to its subsidiary, Mylan Technologies Inc. (MTI), on July 4, 2006.

26 Jul 2006

People with Parkinson disease can be apathetic without being depressed

People with Parkinson disease can be apathetic without being depressed, and apathy may be a core feature of the disease.

10 Jul 2006

Mild sadness provokes depressive thinking in some recovered patients

Some individuals with a history of depression may sink back into thinking patterns associated with the condition when faced with mild stresses or sadness, increasing their risk for relapse.

3 Jul 2006

New drug will treat those winter blues

The U.S. Food and Drug Administration (FDA) has given it's approval for a drug to treat a condition known as Seasonal Affective Disorder (SAD).

14 Jun 2006

Prozac saves thousands of lives

A new study should help alleviate any concern over a link between the use of certain antidepressants and suicide.

13 Jun 2006

FDA approves Wellbutrin X for treatment of seasonal depression

The Food and Drug Administration (FDA) has approved Wellbutrin XL for prevention of major depressive episodes in patients with a history of seasonal affective disorder (SAD).

13 Jun 2006

New tool identifies those at risk of bipolar disorder

According to a new study researchers have identified five predictors for bipolar disorder risk in patients who have been unsuccessfully treated with antidepressants.

23 May 2006

Lilly submits Cymbalta NDA for generalized anxiety disorder

Eli Lilly and Company has announced the recent submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for Cymbalta (duloxetine HCl) for the treatment of generalized anxiety disorder.

10 May 2006

Early transition to menopause may increase risk for first onset of depression

Women with no history of depression may be at an increased risk of new onset depressive symptoms and disorders as they transition to menopause, according to two studies in the April issue of Archives of General Psychiatry.

7 Apr 2006

Menopause linked with the onset of depression

Two new studies say women with no history of depression may be at an increased risk of depressive symptoms and disorders as they enter menopause.

5 Apr 2006

Teenage girls with depression may have a higher risk of physical abuse by their partners

Teenage girls with symptoms of depression may have a higher risk of subsequent physical abuse by their partners than those who don't have symptoms of depression, according to a study in the March issue of Archives of Pediatrics & Adolescent Medicine.

9 Mar 2006

Omega-3 polyunsaturated fatty acids may influence mood, personality and behavior

In a study of 106 healthy volunteers, researchers found that participants who had lower blood levels of omega-3 polyunsaturated fatty acids were more likely to report mild or moderate symptoms of depression, a more negative outlook and be more impulsive.

7 Mar 2006

Eating fish keeps mind as well as heart, happy and healthy

According to researchers in the U.S., Omega-3 polyunsaturated fatty acids may have more of an influence on mood, personality and behavior, than previously thought.

6 Mar 2006

Depression linked to Alzheimer's

A lifetime history of depression is associated with increased plaques and tangles in the brains of those with Alzheimer's disease and more rapid cognitive decline, according to a study by researchers at the Alzheimer's Disease Research Center at Mount Sinai School of Medicine.

9 Feb 2006