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Severe diabetes linked to brain atrophy

Type 2 diabetes may be associated with brain degeneration, according to a new multicenter study published online in the journal Radiology. The study also found that, contrary to common clinical belief, diabetes may not be directly associated with small vessel ischemic disease, where the brain does not receive enough oxygenated blood.

29 Apr 2014

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

Scientists at Icahn School of Medicine at Mount Sinai, along with collaborators at institutions in India, Italy, and Japan, have identified the first gene linked to childhood-onset familial dilated cardiomyopathy (DCM), one of the most common heart muscle diseases in children.

29 Apr 2014

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age.

29 Apr 2014

First Edition: April 28, 2014

Today's headlines include a number of stories examining the impact of the health law in various states.

28 Apr 2014

Women who had chemotherapy less likely to be employed 4 years later

Nearly one-third of breast cancer survivors who were working when they began treatment were unemployed four years later. Women who received chemotherapy were most affected, according to a new study from the University of Michigan Comprehensive Cancer Center.

28 Apr 2014

Skin Cancer Awareness Month and Melanoma Monday: Mount Sinai experts to share vital skin cancer tips

Skin cancer is the most common form of cancer in the United States, with one in five Americans developing it over the course of their lives. It's also one of the most preventable types of cancers. In recognition of May's Skin Cancer Awareness Month and Melanoma Monday on May 5th, Mount Sinai Health System experts are arming the public with vital tips on prevention and offering FREE skin cancer screenings.

26 Apr 2014

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

There's a civil war going on inside every one of the 37 trillion cells in your body. Now, University of Michigan scientists have uncovered how your cells keep this war from causing too much collateral damage.

26 Apr 2014

Professor wins 2014 Outstanding Scientific Achievement Award from American Diabetes Association

Dr. Joel Elmquist, Director of the Center for Hypothalamic Research at UT Southwestern Medical Center, has been awarded the American Diabetes Association's Outstanding Scientific Achievement Award, the organization's top honor for an early-career scientist.

26 Apr 2014

MGH investigators develop next-generation genome editing system

A next-generation genome editing system developed by Massachusetts General Hospital investigators substantially decreases the risk of producing unwanted, off-target gene mutations. In a paper receiving online publication in Nature Biotechnology, the researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites.

26 Apr 2014

NIH award reflects urgency of overcoming infections that resist drug treatment

The National Institute of Allergy and Infectious Diseases of the National Institutes of Health has selected infectious disease expert David Perlin, executive director of the Public Health Research Institute at Rutgers New Jersey Medical School, to lead a major research effort aimed at developing new forms of antibiotics to regain the upper hand over deadly bacteria that have become resistant to current treatments.

26 Apr 2014

Promising new approach targets cancer protein to slow tumor growth

Sometimes a full-on assault isn't the best approach when dealing with a powerful enemy. A more effective approach, in the long run, may be to target the support system replenishing the supplies that keep your foe strong and ready for battle.

26 Apr 2014

Lilly launches second medical student education program

Eli Lilly and Company announced today the launch of another medical student education program, an internship for aspiring physicians.

26 Apr 2014

Researchers uncover Noxa and MCL-1 as potential targets for small cell lung cancers therapies

Approximately 15 percent of all lung cancers are small cell lung cancers (SCLC), which grow rapidly and often develop resistance to chemotherapy. However, researchers at Virginia Commonwealth University Massey Cancer Center have revealed new insights into the mechanisms leading to this resistance that may lead to improved therapies.

25 Apr 2014

Aspirin can lower colon cancer risk among people with high levels of specific gene

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.

25 Apr 2014

State highlights: Ohio hospital merger struck down; Okla. abortion drug use limited; Calif. exchange and felons

A federal appeals court on Tuesday ordered a major health system in northwest Ohio to unwind its merger with a local hospital on antitrust grounds. The unanimous decision by a three-judge panel of the Sixth U.S. Circuit Court of Appeals in Cincinnati comes amid growing concerns about hospital mergers and their effect on prices against the backdrop of America's health care upheaval (Gershman, 4/22).

25 Apr 2014

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body.

25 Apr 2014

Two sedative drugs effectively treat prolonged seizures in children

The sedative drugs diazepam (Valium) and lorazepam (Ativan) are equally effective in treating the prolonged seizures known as status epilepticus in children, according to a randomized, controlled study by a multi-institution team of researchers with the Pediatric Emergency Care Applied Research Network, including an expert from the Perelman School of Medicine at the University of Pennsylvania.

25 Apr 2014

Medical School News and Research

Severe diabetes linked to brain atrophy

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

First Edition: April 28, 2014

Women who had chemotherapy less likely to be employed 4 years later

Skin Cancer Awareness Month and Melanoma Monday: Mount Sinai experts to share vital skin cancer tips

University of Michigan scientists uncover how cells block mutation-causing activity of junk DNA

Professor wins 2014 Outstanding Scientific Achievement Award from American Diabetes Association

MGH investigators develop next-generation genome editing system

NIH award reflects urgency of overcoming infections that resist drug treatment

Promising new approach targets cancer protein to slow tumor growth

Lilly launches second medical student education program

Researchers uncover Noxa and MCL-1 as potential targets for small cell lung cancers therapies

Aspirin can lower colon cancer risk among people with high levels of specific gene

State highlights: Ohio hospital merger struck down; Okla. abortion drug use limited; Calif. exchange and felons

Measuring tumors' oxygen levels could help doctors make decisions about treatments

Two sedative drugs effectively treat prolonged seizures in children

Studies report new genetic disorder associated with degeneration of central/peripheral nervous systems

First Edition: April 23, 2014

New multi-disciplinary project to examine what works best for abused children

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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