Metabolic Disease News and Research

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Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

A new paper published in JAMA Network Open discusses the relationship between caffeine consumption in pregnancy and the future growth of the offspring.

1 Nov 2022

In utero exposure to flame retardant results in altered brain development in newborn rats

A new study from North Carolina State University shows that exposure in utero to the flame retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats.

24 Oct 2022

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Two of the world's leading authorities on bariatric and metabolic surgery have issued new evidence-based clinical guidelines that among a slew of recommendations expand patient eligibility for weight-loss surgery and endorse metabolic surgery for patients with type 2 diabetes beginning at a body mass index (BMI) of 30, a measure of body fat based on a person's height and weight and one of several important screening criteria for surgery.

21 Oct 2022

Enhanced thermogenesis depends on the circadian clock of adipocytes, study reveals

Mice that eat during the active phase of their daily circadian cycle burn more calories through enhanced thermogenesis, mitigating the development of obesity, researchers report.

21 Oct 2022

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

A new animal study from Katherine Lee, a researcher with the West Virginia University School of Medicine, investigates why individuals with obesity may have a particularly difficult time fending off SARS-CoV-2, the virus that causes COVID-19.

19 Oct 2022

Weight loss gadgets: They provide data to help consumers achieve diet goals, but it still won’t be easy

I felt a special kind of awe, then panic, watching my glucose levels skyrocket for the first time after relishing a cold beer on a sweltering summer evening.

14 Oct 2022

Exercise can favorably modify subcutaneous adipose tissue that can improve metabolic health

Exercise is one of the first strategies used to treat obesity-related health problems like Type 2 diabetes and other cardiovascular disease, but scientists don’t understand exactly how it works to improve metabolic health.

12 Oct 2022

BMI: The mismeasure of weight and the mistreatment of obesity

People who seek medical treatment for obesity or an eating disorder do so with the hope their health plan will pay for part of it. But whether it's covered often comes down to a measure invented almost 200 years ago by a Belgian mathematician as part of his quest to use statistics to define the "average man."

12 Oct 2022

Molecular explanation for the contribution of autophagy to BAT energy metabolism

Obesity is a growing global health problem and its prevalence has tripled since 1975. More than 650 million people are affected by this condition worldwide, and 28% of people in Spain over 18 years of age have this complex pathology. Obesity is linked to conditions such as type II diabetes, cardiovascular disease, osteoarthritis, and certain forms of cancer.

13 Sep 2022

Exposure to blue light may accelerate aging

A new study provides insights into the novel mechanisms through which blue light exposure interferes with non-retinal cell metabolic pathways in flies.

5 Sep 2022

Research suggests a new model of how beige fat biogenesis is controlled

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

17 Aug 2022

What are the risk factors related to COVID-19-related hospitalization and mortality?

In a new study, researchers assessed the risk factors associated with COVID-19-related hospitalization or mortality.

16 Aug 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Temple researcher receives NIH award to study the link between HIV, substance use and heart disease

With prompt diagnosis and the right treatment, people with HIV can live long, healthy lives. In recent years, however, gains in survival among people with HIV have exposed a new concern – an increase in the incidence of early-onset cardiovascular disease associated with long-term HIV.

14 Jun 2022

New analytical method sheds light on enduring mystery about type 2 diabetes

Researchers at Oregon State University have invented a new analytical method that sheds light on an enduring mystery regarding type 2 diabetes: Why some obese patients develop the disease and others don't.

6 Jun 2022

Study demonstrates how the transcription factor C/EBPβ can positively influence fat storage

The chronic nutritional and metabolic disease of obesity is characterized by an excessive increase in body fat and its accumulation in tissues.

20 May 2022