Lung Disease News and Research

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Being a grandparent good for your health, says SLU geriatrician

Note to Mimi, Didi, Gigi, G-Ma and the rest of the gang who have swapped out your own pet names for Grandma: Being a grandparent is good for your health. So says Angela Sanford, M.D., assistant professor of geriatrics at Saint Louis University.

20 Oct 2015

Lung cancer patients undergoing LDCT experience elevated distress before screening

Low-dose computed tomography (LDCT) lung cancer screening is recommended to screen patients with an increased risk of developing lung cancer, but little research regarding the emotional toll of screening has been conducted. Researchers from Stony Brook Cancer Center in Stony Brook, New York found 43 percent of patients undergoing LDCT experienced elevated distress before screening, and one-third of patients experienced continued distress even after being told there was no sign of cancer.

20 Oct 2015

Digital health app facilitates early detection, treatment of COPD exacerbation symptoms

A digital health application for reporting symptoms of Chronic Obstructive Pulmonary Disease (COPD) facilitated early detection and treatment of COPD exacerbation symptoms, according to an analysis from the Temple Lung Center published by Telemedicine and eHealth.

19 Oct 2015

Loyola University successfully performs double-lung transplant in patient with debilitating lung disease

Before he developed a debilitating lung disease, outdoorsman Michael Olson had taken 57 canoe and fishing trips to Canada.

13 Oct 2015

Celtaxsys commences acebilustat phase 2 trial in patients with cystic fibrosis in US

Celtaxsys, a clinical stage drug development company focused on advancing care for patients suffering from orphan inflammatory diseases, announced today the commencement of the US arm of an international phase 2 clinical trial for its flagship compound, acebilustat, in patients with cystic fibrosis (CF).

8 Oct 2015

Health officials to attend International Summit on Tuberculosis and Diabetes in Bali, Indonesia

Health officials from the governments of Indonesia and India will join advocates, civil society groups, researchers and businesses from Asia, Europe, Latin America and North America in Bali, Indonesia on 2-3 November at the world’s first International Summit on Tuberculosis (TB) and Diabetes in an effort to avert a global health crisis.

7 Oct 2015

Sonic hedgehog gene maintains normal physiological state and repair process of adult lungs

The whimsically named sonic hedgehog gene, best known for controlling embryonic development, also maintains the normal physiological state and repair process of an adult healthy lung, if damaged, according to new research from the Perelman School of Medicine at the University of Pennsylvania published online this week in Nature in advance of the print edition.

6 Oct 2015

EU provides €3 million to support research on chronic lung disease

Researchers from Plymouth University Peninsula Schools of Medicine and Dentistry are part of an international consortium which has received funding of almost €3 million from the EU Horizon 2020 programme, to investigate methods to prevent, diagnose and treat non-communicable lung disease (such as asthma and chronic pulmonary obstructive disorder - COPD) in low and middle income countries.

5 Oct 2015

Pitt investigators to lead $15 million federal initiative to manage breathing disorder clinical trials

The University of Pittsburgh Graduate School of Public Health and School of Medicine investigators will be leading a $15 million, five-year federal initiative to manage national clinical trials aimed at developing new treatments for breathing disorders.

5 Oct 2015

New study identifies inflammatory lung disease as risk factor for insulin resistance, diabetes

Numerous studies have identified obesity and poor diet as risk factors for insulin resistance and diabetes. A new study adds another risk factor to the list: inflammatory lung disease. Published in the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology, the study reports that inflammation in the lungs is enough to induce the body-wide inflammation that can lead to insulin resistance.

30 Sep 2015

New report implicates five genetic regions that play major roles in CF disease severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could lead to new therapies.

29 Sep 2015

Occupational exposure to metalworking fluid associated with irreversible lung disease

Occupational exposure to fluid commonly used in metal machining operations may be related to a rare, irreversible lung disease, according to research presented at the European Respiratory Society's (ERS) International Congress today (28 September, 2015).

28 Sep 2015

UK Biobank genetic study shows link between lung disease and smoking behaviour

New research published in The Lancet Respiratory Medicine and presented at this year's European Respiratory Society meeting in Amsterdam presents the first analyses of genetic data from the UK Biobank that reveal new associations with lung disease and smoking behaviour.

28 Sep 2015

SLU participates in Phase III clinical trial to treat early-onset preeclampsia

Saint Louis University is participating in a Phase III clinical trial for a drug to treat early-onset preeclampsia in pregnant women that could increase the length of pregnancy, resulting in improved fetal outcomes and reduced infant mortality.

26 Sep 2015

Amgen gets positive CHMP opinions for Kyprolis (carfilzomib) and BLINCYTO (blinatumomab)

"We are pleased to receive positive CHMP opinions for Kyprolis and BLINCYTO as this is an important step in providing new treatment options for patients in Europe with rare forms of cancer," said Sean E. Harper, M.D., executive vice president of Research and Development at Amgen.

25 Sep 2015

FDA approves LONSURF for treatment of patients with metastatic colorectal cancer

Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), today announced that the U.S. Food and Drug Administration approved LONSURF (trifluridine and tipiracil), formerly known as TAS-102, for the treatment of patients with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

22 Sep 2015

Boehringer Ingelheim, BioMed X apply crowdsourcing approach to establish research team for identifying COPD treatment

Boehringer Ingelheim and BioMed X announced today that they have successfully applied a crowdsourcing approach to establish a research team of outstanding scientists from around the world with bright ideas, who will endeavor to identify new approaches for the treatment of patients with chronic obstructive pulmonary disease (COPD).

21 Sep 2015