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Serum folate deficiency in older people may be associated with heightened dementia and death risks

Low levels of folate (vitamin B9) in the blood may be linked to a heightened risk of dementia and death from any cause in older people, suggests research published online in the journal Evidence Based Mental Health.

16 Mar 2022

Novel MRI approach can identify brain cell damage in people at early stages of Alzheimer's

Alzheimer's disease usually is diagnosed based on symptoms, such as when a person shows signs of memory loss and difficulty thinking.

2 Mar 2022

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

1 Mar 2022

Pioneering technique uses a magnetic device to stimulate touch sensitive brain glial cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

24 Feb 2022

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases.

21 Feb 2022

Researchers develop new potential method for treating Alzheimer's disease

Researchers at the faculty have developed an artificial intelligence (AI) method to help them identify potential new medicines for Alzheimer's. The new medicine seems to be more precise. No side effects were documented during tests with worms and mice.

4 Feb 2022

Study finds more than 1,000 gene-activation differences between female and male mouse brains

Male and female mouse brains differ in important ways, according to a new study led by Stanford Medicine investigators.

22 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Alzheimer’s disease risk genes disturb the brain protective mechanism

The brain has a natural protective mechanism against Alzheimer's disease, and researchers at Baylor College of Medicine, Texas Children's Hospital and collaborating institutions have discovered that gene variants associated with risk of developing the disease disturb the protective mechanism in ways that can lead to neurodegeneration.

3 Jan 2022

Inhaled CBD shrinks glioblastoma’s size in an animal model

Inhaled CBD shrinks the size of the highly aggressive, lethal brain tumor glioblastoma in an animal model by reducing the essential support of its microenvironment, researchers report.

24 Dec 2021

Study identifies genetic causes of sudden unexplained deaths in children aged 1 year and older

A new study found that changes in specific genes may contribute each year to the roughly 400 sudden unexplained deaths in children (SUDC) aged 1 year and older—and separately from sudden infant death syndrome (SIDS).

20 Dec 2021

New tool provides an unprecedented view of brain cell activity in a synapse

To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice — all at the same time — when the animals' whiskers are tweaked, an indicator for learning.

20 Dec 2021

Rare population of toxic senescent cells in the brain could be a target for Alzheimer's treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

11 Dec 2021

New optogenetic tool can control brain circuits, behavior, and emotion

Controlling signal transmission and reception within the brain circuits is necessary for neuroscientists to achieve a better understanding of the brain's functions.

30 Nov 2021

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

UVA researchers develop a noninvasive surgical approach to remove faulty brain circuits

University of Virginia School of Medicine researchers have developed a noninvasive way to remove faulty brain circuits that could allow doctors to treat debilitating neurological diseases without the need for conventional brain surgery.

25 Nov 2021

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety.

20 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Researchers receive $8.9 million grant to study the gut-brain connection in Parkinson’s disease

Dr. Michael Kaplitt, a professor of neurological surgery at Weill Cornell Medicine and a longtime leader in developing cutting-edge surgical therapies for movement disorders, leads a team that has been awarded a three-year, $8.9 million grant from the Aligning Science Across Parkinson's (ASAP) initiative.

26 Oct 2021

UVA researchers identify an unknown trigger for epilepsy seizures

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epilepsy seizures.

20 Oct 2021