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Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR).

1 Aug 2024

Indoor fireplaces linked to harmful airborne particles and health risks

During the cold winter months, it is nice to light an indoor fireplace for extra warmth or to have the occasional ‘braai’. The downside is that you may be inhaling tiny solid or liquid substances that could be harmful to your health.

1 Aug 2024

Nasal COVID-19 vaccine shows promise in preventing virus spread

The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern science and saved millions of lives.

31 Jul 2024

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's.

31 Jul 2024

New mucus-based bioink for 3D printing functional lung tissue

Lung diseases kill millions of people around the world each year. Treatment options are limited, and animal models for studying these illnesses and experimental medications are inadequate.

30 Jul 2024

UVA researchers identify a potential treatment for respiratory symptoms of long COVID

University of Virginia School of Medicine researchers have identified a potential treatment for the respiratory symptoms of long COVID after discovering an unknown cause of the condition inside the lungs.

30 Jul 2024

Maternal immune response to flu linked to fetal brain changes

A bad case of the flu during pregnancy can increase the risk for fetal neurodevelopmental disorders such as schizophrenia and autism spectrum disorder. But it's not the virus itself doing the damage; it's the mother's immune response.

29 Jul 2024

Dogs with gallbladder disease shed light on human cystic fibrosis

A canine gallbladder disease that involves the accumulation of abnormal mucus similar to that seen in human cystic fibrosis (CF) patients is caused by improper expression of the gene associated with CF in humans.

29 Jul 2024

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of those suffering from respiratory disease, today announced dosing of the first person with cystic fibrosis (pwCF) in its Phase 2a trial of ETD001.

24 Jul 2024

Ohio State leads multi-million dollar research on long COVID solutions

A 2022 study suggesting that blocking a single molecule could protect against severe illness in COVID-19 has led to a $15 million federal grant supporting a comprehensive effort to learn more – with finding a solution to long COVID at the center of the new research.

23 Jul 2024

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors.

23 Jul 2024

E-Cigarettes and Ethanol: A Forensic Perspective on Vaping

In this interview conducted at Pittcon 2024 in San Diego, we spoke to Professor Michelle Peace about the challenges and implications of detecting ethanol in e-cigarettes for drug testing and forensic toxicology.

From Pittcon 23 Jul 2024

‘A catalyst for revolution’: Launch of Thrive looks to safeguard public health

Brisbane is positioned to become the global hub for healthy buildings with today's launch of the ARC Training Centre for Advanced Building Systems against Airborne Infection Transmission (Thrive).

23 Jul 2024

Synthetic solutions for ethical and effective drug testing

Improving human quality of life with drug treatments is a complicated issue. Drug certification, including drug safety and reliability, entails a long series of tests and government approvals before the drug is available for anyone to use.

22 Jul 2024

Study reveals a promising approach to developing universal influenza vaccine

New research led by Oregon Health & Science University reveals a promising approach to developing a universal influenza vaccine -; a so-called "one and done" vaccine that confers lifetime immunity against an evolving virus.

19 Jul 2024

Porcine study reveals meurotoxic and pro-inflammatory effects of microplastics on enteric nervous system

Researchers investigates the effects of polyethylene terephthalate microplastics on the neuronal population in the porcine jejunum.

18 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

Burning ammonia for maritime fuel could lead to devastating public health impacts

As container ships the size of city blocks cross the oceans to deliver cargo, their huge diesel engines emit large quantities of air pollutants that drive climate change and have human health impacts.

11 Jul 2024

Prime editing offers promising path to permanent treatment for cystic fibrosis

Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection.

11 Jul 2024

Lungs News and Research

Study elucidates mechanisms behind G protein selectivity and efficacy in adenosine A2A receptor

Indoor fireplaces linked to harmful airborne particles and health risks

Nasal COVID-19 vaccine shows promise in preventing virus spread

Exosome-encapsulated fluorescent sensors enable advanced brain imaging in Alzheimer's research

New mucus-based bioink for 3D printing functional lung tissue

UVA researchers identify a potential treatment for respiratory symptoms of long COVID

Maternal immune response to flu linked to fetal brain changes

Dogs with gallbladder disease shed light on human cystic fibrosis

Enterprise Therapeutics doses first person with cystic fibrosis in Phase 2 trial for novel therapy ETD001

Ohio State leads multi-million dollar research on long COVID solutions

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

E-Cigarettes and Ethanol: A Forensic Perspective on Vaping

‘A catalyst for revolution’: Launch of Thrive looks to safeguard public health

Synthetic solutions for ethical and effective drug testing

Study reveals a promising approach to developing universal influenza vaccine

Porcine study reveals meurotoxic and pro-inflammatory effects of microplastics on enteric nervous system

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Burning ammonia for maritime fuel could lead to devastating public health impacts

Prime editing offers promising path to permanent treatment for cystic fibrosis

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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