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Unmet social needs negatively impact quality of life of dementia patients and caregivers

People with dementia and those who care for them should be screened for loneliness, so providers can find ways to keep them socially connected, according to experts at UC San Francisco and Harvard, who made the recommendations after finding that both groups experienced declines in social well-being as the disease progressed.

18 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

Study reveals why COVID-19 antibodies fade quickly

Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection.

18 Mar 2024

Unlocking weight loss through exercise mimicry with metformin

An "anti-hunger" molecule produced after vigorous exercise is responsible for the moderate weight loss caused by the diabetes medication metformin, according to a new study in mice and humans.

18 Mar 2024

Glucose fluctuations impact cognitive function in people with Type 1 Diabetes

A new study led by researchers at McLean Hospital (a member of Mass General Brigham) and Washington State University used advances in digital testing to demonstrate that naturally occurring glucose fluctuations impact cognitive function in people with Type 1 Diabetes (T1D).

18 Mar 2024

Covid and Medicare payments spark remote patient monitoring boom

Billy Abbott, a retired Army medic, wakes at 6 every morning, steps on the bathroom scale, and uses a cuff to take his blood pressure.

18 Mar 2024

Scientists aim to understand why T cells do not sustain energy in tumors

T cells are often called "assassins" or "killers" because they can orchestrate and carry out missions to hunt down bacteria, viruses, and cancer cells throughout the body.

15 Mar 2024

Machine learning models to predict age from brain transcriptome changes

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 5, entitled, "Genome-wide transcriptome profiling and development of age prediction models in the human brain."

15 Mar 2024

Non-invasive brain stimulation can change specific brain mechanism linked to human behavior

For the first time, researchers at the University of Minnesota Twin Cities showed that non-invasive brain stimulation can change a specific brain mechanism that is directly related to human behavior.

15 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Anxiety therapy prior to COVID-19 pandemic shields against increased stress

The start of the COVID-19 pandemic led to unprecedented exposure to stressors driven by fears of a novel and deadly disease, intense uncertainty, and resulting isolation measures, which in turn resulted in increases in anxiety for many.

14 Mar 2024

Intravascular imaging during PCI in heart disease patients improves survival, reduces adverse outcomes

Using intravascular imaging to guide stent implantation during percutaneous coronary intervention (PCI) in heart disease patients significantly improves survival and reduces adverse cardiovascular events compared to angiography-guided PCI alone, the most commonly used method.

14 Mar 2024

Ultra-processed foods: The new silent killer

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

14 Mar 2024

Identifying social determinants influencing breast cancer screening in the U.S.

There is a pressing need to explore and understand which social determinants of health (SDOH) and health inequities act as significant influential factors that contribute to low breast cancer screening behaviors in the United States.

14 Mar 2024

Novel CAR-T therapy shows promising results in glioblastoma patients

A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment.

13 Mar 2024

Study: Maternal death rates in the U.S. may be overstated due to faulty surveillance

Maternal death rates in the United States may be sharply overstated as a result of faulty surveillance techniques, according to an analysis by researchers at Rutgers Health and other universities.

13 Mar 2024

Novel dual-target CAR T cell therapy shows promise in treating recurrent glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

13 Mar 2024

Novel tool to predict a person's risk for cardiovascular complications after bone marrow transplant

For thousands of Americans each year, a bone marrow transplant has the potential to cure diseases such as leukemias, lymphomas and immune deficiency disorders.

13 Mar 2024

Concerns grow over quality of care as investor groups buy not-for-profit nursing homes

Shelly Olson's mother, who has dementia, has lived at the Scandia Village nursing home in rural Sister Bay, Wisconsin, for almost five years. At first, Olson said, her mother received great care at the facility, then owned by a not-for-profit organization, the Evangelical Lutheran Good Samaritan Society.

13 Mar 2024

Mount Sinai's new department will connect medical care with public health

The Icahn School of Medicine at Mount Sinai, fulfilling its commitment to connecting medical care with public health, today established a new Department of Public Health under the visionary leadership of Rosalind J. Wright, MD, MPH, the Horace W. Goldsmith Professor in Children's Health Research at Icahn Mount Sinai.

12 Mar 2024