Birth Defects News and Research

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Finasteride combined with oral contraceptives may improve female hair loss

Finasteride, a medication approved to treat hair loss in men, may also improve the condition in women when combined with oral contraceptives, according to an article in the March issue of Archives of Dermatology.

21 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

New findings on antidepressants during pregnancy are reason for caution, not alarm

Until recently, antidepressants - especially selective serotonin reuptake inhibitors (SSRIs) - were considered fairly safe for pregnant women.

8 Mar 2006

Vitamin B3 variant reverses effects of fetal alcohol syndrome in mice

A form of vitamin B3 called nicotinamide can reverse the molecular, cellular, and behavioral effects of fetal alcohol syndrome (FAS) in mice, according to a study by physician-scientists at Weill Medical College of Cornell University.

21 Feb 2006

Effects of cancer treatment among children of survivors

Can the high doses of chemotherapy and radiation that young cancer patients receive cause inherited health problems for their children? Vanderbilt-Ingram Cancer Center member, John Boice, Sc.D., and an international team of colleagues have just been awarded a $4 million grant from the National Cancer Institute to try to find out.

21 Feb 2006

Antidepressants may affect fetus

A University of California, San Diego (UCSD) School of Medicine collaborative study with Boston University's Slone Epidemiology Center found an increased risk of persistent pulmonary hypertension (PPHN) in newborns of mothers who used certain commonly prescribed antidepressants in late pregnancy.

20 Feb 2006

Acne drug which causes birth defects too hard to monitor

According to the birth watchdog group the March of Dimes, preventing birth defects from a widely used acne drug is too heavy a burden on doctors, patients and pharmacists.

13 Feb 2006

Stopping antidepressants during pregnancy may lead to relapse

Women who stop taking antidepressant medications during pregnancy are at a five times greater risk for recurrence of depression than are women who continue taking their medication throughout their pregnancies, according to a multi-institutional study published in the Journal of the American Medical Association.

13 Feb 2006

Many women who are eligible for rubella vaccination are not being immunized after giving birth

Contrary to federal recommendations, many women who are eligible for rubella vaccination are not being immunized after giving birth, a new study of Miami-area hospitals has found.

7 Feb 2006

Babies of obese mothers have higher risk of some birth defects

Compared to normal-weight women, overweight and obese women suffer more pregnancy complications and their babies have more medical problems at birth, according to a position paper of the Public Affairs Committee of the Teratology Society.

5 Feb 2006

Pregnancy does not provide protection against depression

Pregnancy has historically been described as a time of emotional well-being, providing "protection" against psychiatric disorder, but a new study says the hormonal changes which occur during pregnancy do not protect women from depression, and those taking antidepressants may need to continue despite concerns about fetal damage.

2 Feb 2006

8 million children born every year with serious birth defects

According to a new report, every year an estimated 8 million children are born with a serious birth defect of genetic or partially genetic origin.

31 Jan 2006

African-American girls have a better chance of survival as premature babies

Extremely premature baby girls, especially those who are African American, are much more likely to survive than extremely premature white boys, according to research published in the January issue of Pediatrics.

26 Jan 2006

Discovery of gene that causes Meckel-Gruber syndrome

The discovery of a gene that causes a rare, inherited and always fatal disorder, Meckel-Gruber (MKS) syndrome, may provide researchers with the common thread to unravel the mysteries of other birth defects.

23 Jan 2006

Identification of Gli protein degradation signals that directly affect tumor latency

Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer.

22 Jan 2006

Identification of gene in childhood kidney disease

An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS). Children with MKS have central nervous system deformities as well as abnormal cysts in their kidneys, and usually die shortly after birth.

16 Jan 2006

More women need to know about folic acid's ability to prevent birth defects

Each year in Minnesota, more than 2,000 babies are born with birth defects. Many of those birth defects likely could have been prevented if the mother had taken enough folic acid.

10 Jan 2006

Thalomid gives hope for blood cancer sufferers

Drug company Celgene says it has halted a pivotal-stage trial of its Thalomid drug earlier than expected after the drug was shown to dramatically limit the progress of the blood cancer multiple myeloma.

9 Jan 2006

National estimates for 18 specific major birth defects between 1999 and 2001

Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience – not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with facial defects.

5 Jan 2006