Neurodegenerative Diseases News and Research

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Mild exposure to single blast can induce meaningful pathogenic effects, study shows

As many as 300,000 United States service members deployed to Iraq and Afghanistan since 2001 have suffered traumatic brain injury due to explosions. The vast majority of these blast-induced traumatic brain injuries, or bTBIs, were classified as mild.

12 Nov 2018

UCPH researcher receives prize for research into brain's cleaning system

Professor Maiken Nedergaard from the University of Copenhagen is this year's recipient of the prestigious prize Stora Nordiska Pris awarded by the Eric K. Fernström Foundation. She receives the prize for her discovery of and research into the brain's cleaning system, the glymphatic system.

8 Nov 2018

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Researchers at the Faculty of Medicine, University of Helsinki, make an unexpected and vital contribution to an international collaborative effort in Parkinson's disease research.

7 Nov 2018

Scientists to discuss latest research on spatial cognition in aging and neurodegeneration

Scientists from Germany and abroad will be meeting in Magdeburg from 27 to 29 November 2018 to discuss latest research on spatial cognition in aging and neurodegeneration. The symposium is hosted by the German Center for Neurodegenerative Diseases.

7 Nov 2018

UCV researchers discover the influence of exosomes on age-related macular degeneration

Researchers of the Neurobiology and Neurophysiology team of the Medicine Faculty at Valencia Catholic University, headed by Jorge Bacia, have discovered that exosomes - microscopic extracellular vesicles that are released by all cells - from the retinal pigment epithelium lead to cases of neovascularization, a finding which could be closely related to similar processes in age-related macular degeneration.

2 Nov 2018

New encyclopedia for adult and pediatric neuropsychological disorders

John DeLuca, PhD, a clinical neuropsychologist and Senior Vice President of Research and Training at Kessler Foundation, is the co-chief editor of the new 2nd edition "Encyclopedia of Clinical Neuropsychology". Published by Springer, it is the first major encyclopedia of adult and pediatric neuropsychological disorders.

2 Nov 2018

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), together with researchers from the USA, have discovered that zinc can activate an organic molecule, helping to protect against oxidative stress.

2 Nov 2018

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

Integral Molecular, the industry leader in membrane protein technologies, was awarded a Small Business Innovation Research grant from the NIH to initiate a target discovery program for Alzheimer's disease.

1 Nov 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

FDA approves ultra-high-field 7T Terra MRI scanner for clinical use

The ultra-high-field 7T Terra magnetic resonance imaging scanner at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute of the Keck School of Medicine of USC has received FDA approval for clinical use, opening up new avenues of care for patients with Alzheimer's disease, multiple sclerosis and other diseases that affect the brain.

31 Oct 2018

Biogen and Eisai present detailed results from phase 1b study of aducanumab at CTAD meeting

Biogen and Eisai Co., Ltd. announced that Biogen presented results at the Clinical Trials on Alzheimer's Disease meeting, in Barcelona, Spain, from the recent 36- and 48-month analyses of the ongoing long-term extension of the Phase 1b study of aducanumab, an investigational treatment for mild cognitive impairment due to Alzheimer's disease and mild AD.

29 Oct 2018

Scientists determine normal function of gene associated with ALS and FTD

The normal function of a gene associated with the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia has been determined for the first time by University of Bath scientists.

24 Oct 2018

New study finds evidence that animals can judge time

Are you taking your time when feeding your pet? Fluffy and Fido are on to you -- and they can tell when you are dawdling.

24 Oct 2018

Researchers produce artificial antibody capable of blocking prions in the laboratory

Prion diseases affect the brain, causing neurodegenerative problems that always lead to death. They attracted attention in the late 1990s due to the "Mad Cow" scare.

22 Oct 2018

Study reveals connection between two proteins known to be hyperactive in cancer

A team of researchers at Baylor College of Medicine and Texas Children's Hospital has revealed a connection between mTORC1 and Src, two proteins known to be hyperactive in cancer.

20 Oct 2018

Prion strain diversity may be greater than previously thought

The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a study published October 18 in the open-access journal PLOS Pathogens by Jason Bartz of Creighton University, and colleagues.

19 Oct 2018

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

A group of Massachusetts General Hospital investigators is proposing that targeting immune checkpoints - molecules that regulate the activity of the immune system - in immune cells called microglia could reduce the inflammatory aspects of important neurodegenerative diseases like Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.

17 Oct 2018

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Lack of sleep during adolescence and early adulthood accelerates Alzheimer’s disease-related tau pathology, finds a study of male and female mice published in JNeurosci.

17 Oct 2018

Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Neurodegenerative Diseases News and Research

Mild exposure to single blast can induce meaningful pathogenic effects, study shows

UCPH researcher receives prize for research into brain's cleaning system

New discovery confirms central importance of PINK1-Parkin pathway in Parkinson's patients

Scientists to discuss latest research on spatial cognition in aging and neurodegeneration

UCV researchers discover the influence of exosomes on age-related macular degeneration

New encyclopedia for adult and pediatric neuropsychological disorders

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

FDA approves ultra-high-field 7T Terra MRI scanner for clinical use

Biogen and Eisai present detailed results from phase 1b study of aducanumab at CTAD meeting

Scientists determine normal function of gene associated with ALS and FTD

New study finds evidence that animals can judge time

Researchers produce artificial antibody capable of blocking prions in the laboratory

Study reveals connection between two proteins known to be hyperactive in cancer

Prion strain diversity may be greater than previously thought

Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation

Chronic sleep disruption in early adult life accelerates AD-related tau pathology

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

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