Neurodegenerative Diseases News and Research

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Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Vast majority of dementia cases may arise from spontaneous genetic errors

Only a small proportion of cases of dementia are thought to be inherited - the cause of the vast majority is unknown.

15 Oct 2018

'Eye scan' shows promise to diagnose central nervous system disorders

Partners from Austria – represented by Medical University of Vienna – Germany, France and the Netherlands are taking part in the EU "MOON" project (multimodal optical diagnostics for age-related diseases of the eye and central nervous system) to develop new techniques for early diagnosis of these diseases and successfully apply them in treatment and diagnosis.

12 Oct 2018

'Digital brain' recreates protein trafficking in the brain

Researchers have developed a digital 3D brain demonstrating how the toxic proteins involved in neurodegenerative diseases are transported through the brain.

12 Oct 2018

Insulin-binding protein in fruit flies could help tackle disease-carrying mosquitos

An insulin-binding protein in fruit flies could provide new opportunities for tackling disease-carrying mosquitos, such as malaria and yellow fever, scientists at the University of York have found.

12 Oct 2018

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Anthony Fitzpatrick, PhD, a Principal Investigator at Columbia's Zuckerman Institute and Columbia University Irving Medical Center, together with scientists from the Mayo Clinic and Boston Children's Hospital, has been awarded $11.3 million to map the three-dimensional structures of protein tangles that accumulate in the human brain.

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Researchers discover previously unknown function of key component in the immune system

The complement proteins that circulate in our blood are an important part of our immune system. They help identify bacteria, viruses and other harmful organisms, making it easier for our white blood cells to find and neutralize dangerous microbes.

5 Oct 2018

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

4 Oct 2018

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

The Neurobiotechnology research team of the Universitat Jaume I in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, helping reverse brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity.

3 Oct 2018

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Alzheimer’s disease researchers makes significant breakthroughs

Researchers in Sweden and United Kingdom have made a breakthrough in Alzheimer’s disease research. They could soon be on the path to develop new drugs that could fight the disease more effectively.

26 Sep 2018

Study reveals structure of potential drug target in neurological conditions

Researchers at Van Andel Research Institute (VARI) have revealed the atomic-level structure of a protein that could serve as a promising new drug target for the treatment of neurological conditions such as bipolar disorder and Alzheimer’s disease.

25 Sep 2018

New model enables anyone to run powerful simulations, complex calculations easily

Imagine a world in which complex calculations that could help improve someone’s health, clean up our planet or test an entrepreneur’s big idea don’t require specific skills.

25 Sep 2018

DFG establishes nine new Research Units

The Deutsche Forschungsgemeinschaft is establishing nine new Research Units, following a decision by the Senate and the Joint Committee in Bonn.

25 Sep 2018

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Following the closure of several research programs for Alzheimer's disease, in early 2018 the FDA issued a release entitled "Draft Guidance for Industry: Early Alzheimer's Disease: Developing Drugs for Treatment." Encouraged by the proposed changes in the new guidance, Genervon's research team reported new findings that its drug candidate GM6 attenuates Alzheimer's disease in an early AD transgenic APP mice model.

25 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

Physical activity may have beneficial effects for people with rare Alzheimer's disease

For individuals carrying a genetic mutation that causes Alzheimer's disease, engaging in at least 2.5 hours of physical activity per week may have beneficial effects on markers of Alzheimer's disease brain changes and may delay cognitive decline, according to a new study available online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association as an article in press, corrected proof.

25 Sep 2018

Neurodegenerative Diseases News and Research

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Vast majority of dementia cases may arise from spontaneous genetic errors

'Eye scan' shows promise to diagnose central nervous system disorders

'Digital brain' recreates protein trafficking in the brain

Insulin-binding protein in fruit flies could help tackle disease-carrying mosquitos

Columbia scientist and collaborators receive $11.3 million to find new targets against brain disease

Research team awarded $3.6 million to assess safety of genome editing

Researchers discover previously unknown function of key component in the immune system

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesity

Aggressive breast cancer hijacks normal protective physiological process to survive

Study finds disease-causing mutation in French-Canadians

Alzheimer’s disease researchers makes significant breakthroughs

Study reveals structure of potential drug target in neurological conditions

New model enables anyone to run powerful simulations, complex calculations easily

DFG establishes nine new Research Units

Genervon reports new findings that drug candidate GM6 attenuates Alzheimer's disease in mice model

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

Physical activity may have beneficial effects for people with rare Alzheimer's disease

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