Neurodegenerative Diseases News and Research

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Researchers uncover how cells invite corrupted proteins inside

Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how cells invite inside corrupted proteins that can turn normal proteins corrupt, leading to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.

16 Jul 2018

Researchers identify new region in mouse brain that affects appetite and body weight

Researchers at A*STAR's Singapore Bioimaging Consortium have identified a new region of the mouse brain called the Tuberal Nucleus, which affects appetite and body weight

13 Jul 2018

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine.

12 Jul 2018

UZH scientists identify enzyme that controls cell division

When a cell divides, its constituents are usually evenly distributed among the daughter cells. UZH researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed.

12 Jul 2018

Researchers discover prion-like viral proteins that open new targets for antiviral drugs

Researchers at the Human Microbiology Institute and Tetz Laboratories have discovered thousands of prion-like domains in human viruses, prompting research that opens new ways of viral pathogenicity, suggests new targets for development of new antiviral drugs and links viruses to diseases such as Alzheimer’s and Parkinson’s.

12 Jul 2018

Scientists discover ‘Big Bang’ of Alzheimer's disease

Scientists have discovered a "Big Bang" of Alzheimer's disease - the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.

11 Jul 2018

Study: Vitamin D unlikely to protect individuals from brain-related disorders

New research from South Australian scientists has shown that vitamin D is unlikely to protect individuals from multiple sclerosis, Parkinson's disease, Alzheimer's disease, or other brain-related disorders.

10 Jul 2018

New theory on Huntington's disease shows promise to open new avenues of drug development

McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.

10 Jul 2018

Single-cell RNA sequencing reveals how complex brain circuit works

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

6 Jul 2018

Targeting multiple proteins may be key to treat neurodegenerative disorders

Nearly all major neurodegenerative diseases - from Alzheimer's to Parkinson's - are defined and diagnosed by the presence of one of four proteins that have gone rogue: tau, amyloid-beta, alpha-synuclein, or TDP-43.

6 Jul 2018

Scientists discover brain cell critical to learning and memory

A new study published today reports the identification of a type of brain cell that plays a crucial role in memory and learning processes.

5 Jul 2018

Study: ‘Skinny fat’ may be important predictor of cognitive performance in older adults

A new study has found that "skinny fat" - the combination of low muscle mass and strength in the context of high fat mass - may be an important predictor of cognitive performance in older adults.

5 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Increase in marker of inflammation from mid to late life linked with dementia

Researchers at Johns Hopkins have added to evidence that rising and chronic inflammation as measured by a biomarker in the blood in middle and late age are linked to visible structural changes in the brains of people with poor cognition and dementia.

2 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

Researchers discover inhibitory peptides to target central components in autophagy pathway

Autophagy, meaning "self-eating" in Greek, is a general metabolic mechanism adopted by nearly all the eukaryotic species, from the single cell yeast to humans.

30 Jun 2018

Tau protein allows microtubules to grow and remain dynamic, shows study

A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells.

30 Jun 2018

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

James McNew's and Michael Stern's biochemical hunt for the root cause of a rare, paralyzing genetic disorder is a 10-year quest that's taken an unexpected turn toward everyday killers such as Alzheimer's disease, cancer and aging.

30 Jun 2018

Genes associated with autism interact to modulate variable symptoms of disease

Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.

29 Jun 2018

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer's disease.

29 Jun 2018

Neurodegenerative Diseases News and Research

Researchers uncover how cells invite corrupted proteins inside

Researchers identify new region in mouse brain that affects appetite and body weight

Novel therapeutic approach alleviates ALS-related muscular atrophy in mouse models

UZH scientists identify enzyme that controls cell division

Researchers discover prion-like viral proteins that open new targets for antiviral drugs

Scientists discover ‘Big Bang’ of Alzheimer's disease

Study: Vitamin D unlikely to protect individuals from brain-related disorders

New theory on Huntington's disease shows promise to open new avenues of drug development

Single-cell RNA sequencing reveals how complex brain circuit works

Targeting multiple proteins may be key to treat neurodegenerative disorders

Scientists discover brain cell critical to learning and memory

Study: ‘Skinny fat’ may be important predictor of cognitive performance in older adults

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Increase in marker of inflammation from mid to late life linked with dementia

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

Researchers discover inhibitory peptides to target central components in autophagy pathway

Tau protein allows microtubules to grow and remain dynamic, shows study

Scientists focus on critical regulatory protein to find clues on cancer, neurodegenerative diseases

Genes associated with autism interact to modulate variable symptoms of disease

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

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Why use light scattering to analyze proteins and viral vectors?

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