Kidney Failure News and Research

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1 in 10 new moms diagnosed with high blood pressure in the year after childbirth

In an analysis of more than 2,400 women, about 1 in 10 without a history of blood pressure issues were diagnosed with high blood pressure in the year after childbirth, according to a research article published today in Hypertension, an American Heart Association journal.

15 Nov 2022

Study reveals change in symptoms before and after start of dialysis in older patients with kidney failure

In a study published in CJASN that included older adults with kidney failure, symptoms related to their condition worsened in the year before patients started dialysis but stabilized after dialysis initiation.

11 Nov 2022

Combining surrogate markers of kidney disease progression improves predictions of treatment effects on clinical endpoints

Change in urinary albumin:creatinine ratio (UACR) and glomerular filtration rate (GFR) slope are markers that are individually used as surrogates of chronic kidney disease progression in clinical trials.

6 Nov 2022

Personalized approach to kidney disease screening for T1D patients could enable earlier disease detection

Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

2 Nov 2022

High incidence of CKD in the United States persists, study says

New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds.

1 Nov 2022

Lower risk of colorectal cancer associated with dietary flavanone and anthocyanidin intake, according to new research

In a new study, researchers assessed the risk of colorectal cancer (CRC) with the intake of flavonoids.

31 Oct 2022

Indonesian government orders temporary ban of cough syrups after Gambian tragedy

Following a WHO warning about possible toxic ingredients in four cough syrups of Indian origin, the Indonesian government has ordered a temporary ban on all liquid medicines in the country over reported spike in children's deaths linked to medical syrups.

28 Oct 2022

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Researchers assessed the impact of SARS-CoV-2 vaccination on the occurrence and severity of symptoms in SARS-CoV-2 Omicron-infected hospitalized patients.

27 Oct 2022

Study examines the frequency of concurrent hospice and dialysis care among veterans with ESKD

Today, patients utilizing their Medicare Hospice Benefits with end-stage kidney disease (ESKD) are forced to make the traumatic choice between continuing dialysis or enrolling in hospice.

21 Oct 2022

Pathophysiological mechanisms of COVID-19-related endothelial dysfunction and potential therapies

Researchers discussed the pathophysiological mechanisms of endothelial dysfunction associated with severe coronavirus disease 2019 (COVID-19) and commented on the potential therapeutic strategies to treat endothelial damage and coagulopathy related to COVID-19.

19 Oct 2022

People with end-stage renal disease and psoriasis do not have increased risk for heart attack

Studies have suggested that psoriasis is an independent risk factor for heart attack in the general population, but investigators have made the surprising finding that in people who also have end-stage renal disease, which shares many risk factors with heart disease, it is not.

18 Oct 2022

Scientists show how cellular hypoxia response increases fetal hemoglobin expression in adults

Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults.

12 Oct 2022

DOAC use associated with lower risk of kidney complications in patients with atrial fibrillation

Swedish cohort study shows 13% (95% CI, 2-22%) lower risk of kidney function decline or kidney failure and 12% (95% CI, 3-20%) lower risk of acute kidney injury with use of direct oral anticoagulants vs. vitamin K antagonists for non-valvular atrial fibrillation.

5 Oct 2022

Mortality prediction model for dementia patients may help guide decisions on end-of-life care

A mortality prediction model for older adults with dementia may help clinicians frame discussions with patients and their families relating to end-of-life care, such as at-home support and nursing homes.

26 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Study identifies a promising target for polycystic kidney disease treatment

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

16 Sep 2022

Scientists unravel the molecular origin of rare genetic disease cystinosis

The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.

15 Sep 2022

Study reveals recommended levels of long-term blood sugar to avoid diabetes-related damage

The levels of long-term blood sugar, HbA1c, can be used to accurately determine the risk of a person with type 1 diabetes developing eye- and kidney complications.

12 Sep 2022

Organ transplants are up, but the agency in charge is under fire

For the past decade, Precious McCowan's life has revolved around organ transplants. She's a doctoral candidate studying human behavior in Dallas who has survived two kidney transplants. And in the midst of her end-stage renal disease, her 2-year-old son died. She chose to donate his organs in hopes they would save a life.

7 Sep 2022