Leukocyte News and Research

RSS

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

A new study aimed to develop a standardized protocol for SARS-CoV-2 RNA detection in semen fractions used for assisted reproductive technology.

26 Oct 2022

The impact of existing and theoretical mutations on SARS-CoV-2 CD8+ T cell targets

Researchers evaluated the effect of mutations in SARS-CoV-2 variants of concern on CD8+ T cell responses.

25 Oct 2022

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

New research finds microclotting and inflammatory molecule abnormalities in long-COVID

A new study published on the preprint server medRxiv* determines how endothelial activation and inflammation contribute to the formation of microclots in PASC.

18 Oct 2022

Researchers identify gene associated with strong immune response after COVID-19 vaccination

Researchers from the University of Oxford have today reported new findings from a study exploring how certain genes can help generate a strong immune response following vaccination with two commonly used COVID-19 vaccines - identifying a particular gene associated with a high antibody response.

18 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

In a new study, researchers determined plasma signatures of proteins related to or derived from platelets in acute isolated pulmonary embolism (iPE) and deep vein thrombosis-associated PE (DVT-PE), compared to isolated DVT (iDVT).

17 Oct 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

Nigeria's Oligo synthesizer laboratory, the first in West Africa, could be a game changer in tackling emerging and re-emerging diseases in the region if harnessed to its full potential, laboratory scientists have said.

27 Sep 2022

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

In a new study, researchers demonstrated how sarbecovirus family down-regulates major histocompatibility complex-I (MHC-I) surface expression to evade cellular immunity.

26 Sep 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Immune checkpoint inhibitor (ICI) therapy is a type of treatment for melanoma, the deadliest form of skin cancer, which blocks proteins on tumor or immune cells that prevent the immune system from killing cancer cells.

19 Sep 2022

Mechanism of action of different COVID-19 vaccines

In a recent study posted to the bioRxiv* preprint server, researchers at the University of Tuebingen and Imperial College London assessed humoral and cellular immune responses elicited by the recombinant adenoviral vector (rAdVV)- and messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines.

14 Sep 2022

Leukocyte News and Research

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

The impact of existing and theoretical mutations on SARS-CoV-2 CD8+ T cell targets

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

New research finds microclotting and inflammatory molecule abnormalities in long-COVID

Researchers identify gene associated with strong immune response after COVID-19 vaccination

Study explores the effect of COVID-19 on platelet function

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

How COVID-19 affects the female reproductive system

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

Study demonstrates how pan-sarbecovirus ORF7a protein plays a role in evading host immunity

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Mechanism of action of different COVID-19 vaccines

How does SARS-CoV-2 infection impact fertility in men?

What is the long-term durability of plasma cells in human bone marrow?

Living unrelated donor organ transplants are not inferior to deceased donor organs

Immunology eBook

Exploring the G:Box and for high-quality imaging

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Latest News