Cleft Palate News and Research

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Cleft lip and cleft palate are birth defects that affect the upper lip and roof of the mouth. They happen when the tissue that forms the roof of the mouth and upper lip don't join before birth. The problem can range from a small notch in the lip to a groove that runs into the roof of the mouth and nose. This can affect the way the child's face looks. It can also lead to problems with eating, talking and ear infections.

How cells change the pace of their steps

Scientists at UC San Diego have discovered how cells of higher organisms change the speed at which they move, a basic biological discovery that may help researchers devise ways to prevent cancer cells from spreading throughout the body.

7 Aug 2007

Correcting birth defects

Traditionally when a baby was born with a malformation of the lung or esophagus, they had to undergo open surgery involving a large chest incision with risk for serious complications.

18 Jul 2007

Popular epilepsy drug damages the unborn

A study by researchers in the United States has found that women who took an epilepsy drug during their pregnancy had a higher risk of giving birth to children with a lower IQ or with mental retardation.

7 May 2007

Current arguments for reform of UK Abortion Act

The 40th anniversary in October this year of the passing of the UK Abortion Act is certain to be marked by attempts to reopen the debate about lowering the upper limit for legal terminations. In a special report in this week's British Medical Journal, journalist Jonathan Gornall examines current arguments for reform.

11 Feb 2007

Can non-medical use of ultrasound be justified?

Expectant parent' desire to see images of their unborn children has given rise to commercial companies offering keepsake ultrasound scans without medical supervision, often referred to as "boutique ultrasonography."

5 Feb 2007

Folic acid appears to reduce risk of cleft lip and palate

A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby's chances of being born with a facial cleft.

28 Jan 2007

SUMO1 gene implicated in cleft lip and palate defects

Researchers supported by the National Institutes of Health report in the current issue of the journal Science that a much-studied gene called SUMO1, when under expressed, can cause cleft lip and palate, one of the world's most common birth defects.

21 Sep 2006

Largest review of Loeys-Dietz syndrome to date

At least three severe, potentially fatal genetic diseases leave patients with aortas so flimsy that they can rupture in pregnancy and labor or even lesser activities, often without warning.

31 Aug 2006

Acne drug which causes birth defects too hard to monitor

According to the birth watchdog group the March of Dimes, preventing birth defects from a widely used acne drug is too heavy a burden on doctors, patients and pharmacists.

13 Feb 2006

National estimates for 18 specific major birth defects between 1999 and 2001

Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience – not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with facial defects.

5 Jan 2006

Gene discovery may prevent craniofacial birth defects

Craniofacial researchers have developed an animal model that explains how skull malformations occur and how they might be prevented.

22 Dec 2005

Teens with missing part of a chromosome confirm genetic role in schizophrenia

A study in youth who are missing part of a chromosome is further implicating a suspect gene in schizophrenia.

23 Oct 2005

Gene responsible for Neuralgic Amyotrophy identified

Neuralgic Amyotrophy is a painful disorder of the peripheral nervous system. This heritable disease causes prolonged acute attacks of pain in the shoulder or arm, followed by temporary paralysis.

27 Sep 2005

No intervention is necessary for most children with fluid in their ears

A Children's Hospital of Pittsburgh study finds that prompt insertion of tympanostomy tubes (small ear tubes) does not improve developmental outcomes of children at 6 years of age as once thought.

24 Aug 2005

Removal, restructure and re-implantation of the nasal septum provides option for difficult nasal plastic surgery

A surgical technique that requires the removal, restructure and re-implantation of the nasal septum (the partition of the nose between the nostrils) appears to be a useful option for repairing the hard-to-treat severely deviated septum, according to an article in the July/August issue of Archives of Facial Plastic Surgery.

19 Jul 2005

Global research network needed if scientists are ever going to understand and prevent cleft palate

Professor Bill Shaw, of The University of Manchester, says the complexity of craniofacial anomalies, like cleft lip and palate, means no one country, let alone institution, has the necessary expertise and resources to find all the answers to these distressing conditions.

From The University of Manchester 11 May 2005

Advance in genetics of cleft lip and palate

Cleft lip and/or palate remains one of the most common birth defects in the world. It occurs when the sides of the face fuse abnormally in a developing baby, resulting in a malformed lip and/or roof of the mouth.

12 Apr 2005

Tissue engineering to grow bone, ligaments and cartilage

A future in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major role in treating medical conditions was revealed at a recent Tissue Engineering Symposium at Wake Forest University Baptist Medical Center.

11 Apr 2005

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

A team of scientists from Colombia, the United States and elsewhere has successfully completed a 15-year-plus search for the genetic problems behind the very rare Roberts syndrome, whose physical manifestations often include cleft lip and palate and shortened limbs that resemble those of babies whose mothers took thalidomide during pregnancy.

11 Apr 2005

Disfigured patients may be forced to forego surgery

Increasing insurance company denials, restrictions on covered procedures and a new tactic of excluding specific procedures may be forcing some adults and children to live with painful medical conditions or disfigurement. This restrictive access to care contributed to a 10 percent decline in reconstructive plastic surgery procedures in 2004, according to the latest statistics by the American Society of Plastic Surgeons.

21 Mar 2005