Inflammation News and Research

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Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes. Statins’ effects on both complex compounds appear beneficial in cutting patients’ cardiovascular risks.

6 Jan 2005

New hope for millions of patients suffering from liver damage (cirrhosis)

Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

5 Jan 2005

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe, effective therapy for geriatric patients who can't be helped by medication alone, according to new research.

3 Jan 2005

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

This week, researchers report new findings that clarify the role of NOD2, a key molecular player in Crohn's Disease, in the cellular signaling pathways that control inflammatory responses. NOD2's clinical relevance is clear from the fact that it is encoded by a Crohn's Disease susceptibility gene.

28 Dec 2004

Indian curry may be the next Alzheimer's weapon

A dietary staple of India, where Alzheimer's disease rates are reportedly among the world's lowest, holds potential as a weapon in the fight against the disease.

28 Dec 2004

Seafood research will bring healthier lifestyle

The biggest research project ever sponsored by the EU in the seafood sector will help to meet the consumer demand for more healthy products.

23 Dec 2004

Theory that could help to cure diseases including cancer

An Open University science student has astonished the world of medicine with a theory that could help to cure diseases including cancer.

21 Dec 2004

New advice on anti-inflammatory drugs called Cox-2 Inhibitors, including Celebrex

Patients who are taking Celebrex, Bextra and Arcoxia should make a non-urgent appointment with their GP to review their treatment. Patients who have established heart disease or who are at high risk of stroke will have their treatment changed.

21 Dec 2004

FDA issues advice on Naproxen

The FDA has released the following statement on NIH halting a clinical trial involving non-steroidal anti-inflammatory drugs in patients at risk of developing Alzheimer's Disease:

20 Dec 2004

At-home hand dermatitis treatment with oral medication and use of a portable tanning effective treatment for hand eczema

An at-home hand dermatitis treatment with oral medication and use of a portable tanning unit appears to be as effective as a hospital-based treatment in reducing the symptoms of hand dermatitis, according to an article in the December issue of The Archives of Dermatology.

20 Dec 2004

Stem cells use inflammatory signals to find injured tissue

A joint effort led by stem cell biologist Evan Y. Snyder, M.D., Ph.D., of The Burnham Institute, and Samia J. Khoury, M.D., of Harvard Medical School and Brigham and Women’s Hospital, report data suggesting that stem cells use inflammatory signals to “know” where they must home.

20 Dec 2004

Researchers discover clues to cirrhosis

Researchers at the University of Essex have found new biochemical indicators of cirrhosis in blood plasma which could help detect the disease in its early stages.

20 Dec 2004

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

Researchers at Millennium Pharmaceuticals today announced the discovery of a panel of protein biomarkers that could play a role in the early detection, prognosis and monitoring of rheumatoid arthritis (RA).

14 Dec 2004

Parasitic worms, or helminths, may be an effective treatment for Crohn's disease

Helminths, such as roundworms and threadworms, are rare in developed countries, where rates of Crohn's disease are high. But in developing countries where corresponding rates of the disease are low, many people carry these parasitic worms.

13 Dec 2004

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

The risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs, according to an article in the December issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

13 Dec 2004

Compounds in Christmas trees could help treat arthritis and pain

Researchers have identified a group of anti-inflammatory compounds in the bark of the Scotch pine - widely used for Christmas trees - that they say could be developed into food supplements or drugs for treating arthritis and pain.

13 Dec 2004

Lupus drug may also be useful in treating psoriasis

A new drug candidate previously shown to reduce harmful side effects of the autoimmune disease lupus also may be useful in treating psoriasis.

13 Dec 2004

FDA approves Topigen's investigational New Drug Application for new inhalation drug to treat asthma

Phase 1 clinical trial can be initiated for ASM8, a new inhalation drug that is designed to treat asthma through a unique approach by attacking multiple mediators of the inflammatory mechanism rather than the single mediator approach of current therapies.

8 Dec 2004

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

In laboratory tests on multiple myeloma cells, University of Rochester researchers found that this type of cancer expresses a protein that makes it an easy target for an existing class of diabetes drugs. After more investigation, they hope the discovery will lead to a new, targeted therapy for myeloma patients.

8 Dec 2004

Single dose phase I data on CG53135 for the prevention of oral mucositis

CuraGen Corporation has announced results presented from a Phase I clinical trial with CG53135 for the prevention of oral mucositis (OM) in patients receiving high dose chemotherapy (HDCT) followed by autologous hematopoietic stem cell transplantation (AHSCT) at the ASH 46th Annual Meeting in San Diego, CA.

5 Dec 2004

Inflammation News and Research

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

New hope for millions of patients suffering from liver damage (cirrhosis)

Minimally invasive surgery to alleviate the pain and pressure of sinusitis is a safe

New findings clarify the role of NOD2, a key molecular player in Crohn's Disease

Indian curry may be the next Alzheimer's weapon

Seafood research will bring healthier lifestyle

Theory that could help to cure diseases including cancer

New advice on anti-inflammatory drugs called Cox-2 Inhibitors, including Celebrex

FDA issues advice on Naproxen

At-home hand dermatitis treatment with oral medication and use of a portable tanning effective treatment for hand eczema

Stem cells use inflammatory signals to find injured tissue

Researchers discover clues to cirrhosis

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

Parasitic worms, or helminths, may be an effective treatment for Crohn's disease

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

Compounds in Christmas trees could help treat arthritis and pain

Lupus drug may also be useful in treating psoriasis

FDA approves Topigen's investigational New Drug Application for new inhalation drug to treat asthma

Thiazolidinedione (TZD) class of anti-diabetic drugs may be a potential targeted therapy for myeloma patients

Single dose phase I data on CG53135 for the prevention of oral mucositis

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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