Aortic Stenosis News and Research

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Study challenges early intervention for asymptomatic aortic stenosis

The EVOLVED trial found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis (AS) and mid-wall myocardial fibrosis on magnetic resonance imaging did not reduce the incidence of the composite primary endpoint of all-cause death or unplanned aortic stenosis hospitalization compared with guideline-directed conservative management.

30 Oct 2024

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

29 Oct 2024

Early intervention with TAVR proves safe and effective for asymptomatic aortic stenosis

The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).

29 Oct 2024

European Society of Cardiology highlights underrecognized link between obesity and heart disease

Obesity is a key factor in cardiovascular disease, prompting the ESC to recommend comprehensive strategies for prevention and management to reduce health risks.

3 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

TAVI outperforms surgery in reducing complications for women with severe aortic stenosis

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI patients with coronary artery disease can derive benefits from percutaneous coronary intervention

Performing percutaneous coronary intervention (PCI) significantly improved outcomes in patients with stable coronary artery disease (CAD) and severe aortic stenosis selected for transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

Virtual voice technology enhances follow-up care for TAVI patients

Clinical follow-up using virtual voice technology helped identify complications after transcatheter aortic valve implantation (TAVI) with a high degree of patient satisfaction, according to research presented at ESC Congress 2024.

27 Aug 2024

Medical device may aid stroke survivors during heart valve replacement procedure

Recently published research shows a medical device may be beneficial for patients who have previously had a stroke and are planning to undergo a transcatheter aortic valve replacement, a type of heart valve operation.

31 Jul 2024

Stratifying TAVI candidates with degenerative MR: Prognostic considerations

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transcatheter aortic valve implantation (TAVI) has emerged as the primary treatment strategy for severe symptomatic aortic stenosis (AS) in the older population (>75 years of age) with high-risk surgical profiles.

18 Jul 2024

UK coronary heart disease drops 30%, but other heart conditions rise

Researchers investigated the overall incidence of cardiovascular disease in the United Kingdom from 2000 to 2019.

1 Jul 2024

Integrated cellular map of heart cells unlocks cardiac fibrosis process

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

21 Jun 2024

Medtronic’s Evolut valve reduces dysfunction, improves quality of life in women with severe aortic stenos

Medtronic, the global leader in healthcare technology, today announced new data from the largest head-to-head comparative trial of transfemoral transcatheter aortic valve replacement (TAVR), the SMall Annuli Randomized To Evolut or SAPIEN (SMART) Trial, looking exclusively at women.

20 May 2024

Study shows comparable outcomes for TAVR and SAVR in aortic valve replacement

A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart-;transcatheter aortic valve replacement (TAVR)-;and surgical aortic valve replacement (SAVR).

15 May 2024

SMART study shows hemodynamic benefits of self-expanding valves in aortic stenosis patients

Additional analysis from the SMall Annuli Randomized To Evolut or SAPIEN (SMART) study demonstrated clinical non-inferiority of self-expanding valves (SEV) versus balloon-expandable valves (BEV) in aortic stenosis patients undergoing transcatheter aortic valve replacement (TAVR) and confirmed valve performance superiority over time based on hemodynamics.

3 May 2024

New transcatheter heart valve shows promise in treating aortic stenosis

Recent findings from a study on a transcatheter heart valve (THV) system, which includes a new class of transcatheter aortic valve, showed positive results in the device's ability to function as a healthy and natural aortic valve in patients with aortic stenosis (AS).

3 May 2024

TAVR demonstrates lower risk and improved outcomes compared to SAVR in low-risk patients

Transcatheter aortic valve replacement (TAVR) was found to bring no increased risks and was associated with substantial decreased rates of death or stroke at one year in low-risk patients, compared with surgical aortic valve replacement (SAVR), according to findings presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Age-based comparison of TAVR outcomes in Vietnamese patients with aortic stenosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The increasing number of elderly patients with severe aortic valve stenosis undergoing transcatheter aortic valve replacement (TAVR) has prompted concerns regarding their clinical outcomes compared with the younger population.

5 Mar 2024

Many young patients choose TAVR despite better long-term survival with surgery

Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis, many hospitals are still opting for a nonsurgical approach in patients under 60-;possibly with poorer survival rates.

29 Jan 2024