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Screening approved medicines reveals potential treatments for preterm labor

Shajila Siricilla, PhD, Assistant Professor of Pediatrics, and Jennifer Herington, PhD, Associate Professor of Pediatrics, led a team that systematically screened 1,191 FDA-approved drugs and found that several candidates met criteria supporting further evaluation as potential treatments for preterm labor.

23 Sep 2026

Experimental drug reverses multiple sclerosis damage in mouse model

A drug developed by a UVA Health scientist has not only stopped but reversed paralysis and vision loss in a mouse model of multiple sclerosis.

23 Sep 2026

Brain organoids reveal new clues for childhood epilepsy treatments

Tiny, year-old human brain organoids that mimic the brain of a newborn are providing new clues to potential treatments for a leading genetic cause of childhood epilepsy that typically manifests as the brain matures shortly after birth.

23 Sep 2026

Pharmacist-led reviews improve medication strategies for older cancer patients

There is a pressing need to optimize medication strategies in older adults with cancer, many of whom take ≥5 medications.

23 Sep 2026

New slow-release drug delivery system provides weeks of pain-numbing anesthetic effects

Most local anesthetics used in medicine only last eight to 12 hours or a day tops. Now Boston Children's Hospital researchers have formulated a more effective slow-release injectable drug delivery system that achieved pain-numbing anesthetic effects lasting two to three weeks in rats compared to a commercial formulation lasting about four to eight hours.

23 Sep 2026

Ketamine-related bladder problems reported among young teenagers

Non-prescribed ketamine use may start at the age of 13, suggest data from a UK clinic dedicated to the treatment of bladder problems associated with misuse of the drug and published in a clinical letter in the Archives of Disease in Childhood.

22 Sep 2026

A 30-day benznidazole regimen offers safer Chagas disease treatment option

A 30-day course of benznidazole taken once a day could offer people with chronic Trypanosoma cruzi infection a safer and more practical option than the current standard treatment, taken twice a day for 60 days.

22 Sep 2026

Study identifies potential resistance mechanism in metastatic uveal melanoma

Uveal melanoma is a rare and aggressive cancer that starts inside the eye and often spreads to the liver. Few treatment options exist, and unlike some forms of skin melanoma which can respond well to modern therapies, metastatic uveal melanoma (MUM) remains difficult to treat.

22 Sep 2026

CAR T-cell therapy enables safe pregnancies in autoimmune patients

Autoimmune diseases such as systemic lupus erythematosus mainly affect young women, often in a phase of their lives where they would like to have children.

22 Sep 2026

WashU expert analyzes FTC settlements with major pharmacy benefit managers

The Federal Trade Commission's settlements with two of the nation's largest pharmacy benefit managers (PBMs) could change how the companies do business, but they may not do enough to lower prescription drug costs for patients and employers, according to a health law expert at Washington University in St. Louis.

22 Sep 2026

Marine carbohydrates offer valuable new resources for drug development

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

22 Sep 2026

Experimental RNA therapy enhances weight loss while preserving lean muscle

GLP-1 drugs have revolutionized obesity treatment, but they can lead people to lose muscle mass along with fat. And when patients stop treatment, they often regain their weight - primarily as fat.

21 Sep 2026

Wearable microneedle patch tracks antibiotic levels in real time

A wearable patch with microneedles coated in DNA molecules tracks levels of antibiotics in the body in real time.

21 Sep 2026

SARS-CoV-2 protein ORF8 drives macrophage infection and lung inflammation

In the sickest COVID-19 patients, the SARS-CoV-2 virus doesn't just cause severe damage by directly infecting airway cells.

18 Sep 2026

New national guidelines developed to improve sepsis-related care

A UVA Health doctor and other leading national experts have developed important new guidelines to improve care for patients who develop sepsis, a dangerous full-body infection that kills at least 350,000 Americans every year.

18 Sep 2026

Researchers create virtual cells to accelerate drug discovery efforts

Mitochondria - tiny structures that convert nutrients into energy - are often depicted as discrete kidney bean-shaped objects.

18 Sep 2026

New discovery overturns a prevailing model of brain development

For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years.

18 Sep 2026

Persistent stigma creates barriers to modern HIV prevention methods

For decades, HIV (human immunodeficiency virus) has been surrounded by fear, misinformation and stigma.

18 Sep 2026

Chronic stress and inflammation cause silent structural heart damage

Chronic stress from people's everyday lives may be causing lasting structural changes to the heart, harming health and reducing life expectancy.

18 Sep 2026

Big Picture Bio founded to identify, design and optimize promising cancer combination therapies

Big Picture Bio Ltd., has been founded to identify, design and optimize promising cancer combination therapies, using a generative world model to understand how tumors, immune cells and surrounding tissue interact across disease sites and patient subgroups.

From Big Picture Bio 18 Sep 2026