Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Newly identified cells protect lung tumors from immune attacks

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

27 Aug 2026

Combined bio-histological score prevents overtreatment in liver transplant patients

Long‑term outcomes after liver transplantation remain hampered by complications linked to intensive immunosuppression—infections, cardiovascular events, kidney dysfunction, and metabolic disorders affect 10% to 40% of recipients.

24 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

Outfitting cells in "invisibility cloaks" could offer a novel approach to treating diabetes

Outfitting cells in "invisibility cloaks" may offer an easier, less damaging treatment pathway for people with diabetes undergoing cell therapy, according to researchers at Penn State.

14 Aug 2026

Study uncovers hidden switch that helps cancer cells to evade immune detection

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have uncovered a previously unknown mechanism that helps cancer cells evade detection by the body's immune system.

13 Aug 2026

Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also persisted during convalescence and were associated with physical deficits in long COVID, although the study did not establish causation.

7 Aug 2026

Localized biochemical halo of IL-10 suppresses immune rejection of pancreatic beta cells

A protein known as interleukin 10 (IL-10) is the lynchpin of a new method to protect transplanted cells from host immune system aggression.

6 Aug 2026

Discovery may help develop new treatments for immunosuppressed skin cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have discovered that immunosuppressed patients with non-melanoma skin cancer are not missing the key cancer-fighting immune cells found in immunocompetent patients, but those cells – known as macrophages – have lost the ability to communicate effectively.

5 Aug 2026

Targeted dendritic cell vaccines emerge as a major step forward in cancer immunotherapy

A major step forward in cancer immunotherapy is emerging through the growing development of dendritic cell vaccines, a highly targeted approach designed to harness the body's own immune system to fight tumors.

5 Aug 2026

AI model predicts effective immunotherapy combinations for liver cancer

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular carcinoma (HCC) would most benefit from combination treatment using immunotherapy and a targeted therapy that blocks the growth signals that the tumor depends on.

15 Jul 2026

Integrating gene signatures and multi omics improves liver cancer treatment

Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers.

14 Jul 2026

Robot-guided surgery successfully drains multiple deep brain abscesses

Brain abscesses located deep within the brain can rapidly become life-threatening and are often difficult to treat through conventional surgery. Brain abscesses located deep within the brain can rapidly become life-threatening and are often difficult to treat through conventional surgery.

13 Jul 2026

New stem cell approach targets functional cure for diabetes

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.

11 Jul 2026

Clinical trial finds stem cell brain transplants feasible for Parkinson's disease

A landmark study led from Lund, Sweden, has shown that transplanting stem-cell derived dopamine progenitor cells into the brain is feasible.

9 Jul 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

Study links severe COVID to higher TB risk, and vaccination appears to blunt the link

A nationwide Chilean cohort study of more than 3.6 million adults found that severe COVID-19 requiring hospitalization was associated with more than an eightfold higher hazard of incident tuberculosis within one year. The association was strongest in the first six months and among unvaccinated individuals, although absolute TB incidence remained low.

1 Jul 2026

Immunosuppression News and Research

Further Reading

Newly identified cells protect lung tumors from immune attacks

Combined bio-histological score prevents overtreatment in liver transplant patients

Glioma microenvironment emerges as key target for future therapies

Outfitting cells in "invisibility cloaks" could offer a novel approach to treating diabetes

Study uncovers hidden switch that helps cancer cells to evade immune detection

Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

Localized biochemical halo of IL-10 suppresses immune rejection of pancreatic beta cells

Discovery may help develop new treatments for immunosuppressed skin cancer patients

Targeted dendritic cell vaccines emerge as a major step forward in cancer immunotherapy

AI model predicts effective immunotherapy combinations for liver cancer

Integrating gene signatures and multi omics improves liver cancer treatment

Robot-guided surgery successfully drains multiple deep brain abscesses

New stem cell approach targets functional cure for diabetes

Clinical trial finds stem cell brain transplants feasible for Parkinson's disease

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Study links severe COVID to higher TB risk, and vaccination appears to blunt the link

Peacemaker immune cells offer new hope for restoring immune tolerance

Immunotherapy helps bridge cancer patients to curative liver transplantation

Novel gene therapy appears to be safe for Friedreich ataxia cardiomyopathy

Researchers uncover immune loop driving Sjögren's disease progression

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