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Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Researchers investigate the clinical efficacy of semaglutide in controlling urine albumin-to-creatinine ratio in overweight patients with chronic kidney disease.

31 Oct 2024

Survey reveals lack of awareness about pancreatic cancer risk among adults under age 50

While pancreatic cancer rates are rising in people under age 50, a new survey conducted by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) shows most people continue to believe that pancreatic disease affects only the elderly – and that there is nothing they can do to reduce their risk.

30 Oct 2024

Urine transcriptomics: A new frontier for non-invasive genitourinary disease detection

Researchers explore the potential diagnostic utility of transcriptomic and metabolic signals in the genitourinary system.

29 Oct 2024

Could vitamin D be the missing link in managing type 2 diabetes? Recent study weighs in

Vitamin D's role in type 2 diabetes management is evolving, with evidence suggesting it may improve blood sugar levels and reduce diabetes-related inflammation.

29 Oct 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research indicates elevated cardiovascular risk in vitiligo patients, underscoring the necessity for enhanced monitoring and preventive healthcare measures.

29 Oct 2024

Research identifies respiratory transmission potential of H5N1 virus

A highly pathogenic avian influenza (HPAI) H5N1 virus, isolated from the eye of a farm worker who became infected through contact with dairy cows, was lethal in mice and ferrets infected in a high-containment laboratory environment, according to a new study in Nature.

28 Oct 2024

New genetic insights reveal kidney disease risk in West Africans

A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria.

28 Oct 2024

NIH grants $2.6 million to explore the effects of high blood-pressure drugs in CKD patients

The National Institutes of Health awarded a four-year, $2.6 million grant to researchers at Case Western Reserve University to study how high blood-pressure drugs affect patients with chronic kidney disease (CKD).

28 Oct 2024

Elucidating the mechanisms behind kidney development

To Alex Hughes, Assistant Professor in Bioengineering within Penn Engineering and in Cell and Developmental Biology within Penn Medicine, the kidney is a work of art. "I find the development of the kidney to be a really beautiful process," says Hughes.

28 Oct 2024

How a proposed federal heat rule might have saved these workers’ lives

On a sweltering afternoon in July 2020, Belinda Ramones got a call that her brother was in the hospital. The call was from a woman at the Florida landscaping business that he had joined that week, the Davey Tree Expert Co., Ramones said. By the time she arrived, she said, "My brother was swollen up from hands to toes."

28 Oct 2024

Study finds pistachios might help guard against vision loss

A study finds that pistachio consumption significantly increases macular pigment optical density, potentially protecting against vision loss in healthy adults.

28 Oct 2024

Ozempic effective for patients with chronic kidney damage

In a 24-week trial, semaglutide led to a 52% reduction in albuminuria and improved kidney health in individuals with chronic kidney disease and obesity.

28 Oct 2024

Clinical trial highlights efficacy of imlifidase for kidney transplant recipients

For kidney transplant recipients experiencing antibody-mediated rejection, the current standard of care involves removing donor-specific antibodies (DSAs) through plasmapheresis (PLEX)-;a procedure that removes antibodies from the plasma portion of the blood.

27 Oct 2024

Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Chronic active antibody-mediated rejection (caAMR) is a common cause of allograft loss after transplantation, with no approved therapies. Clazakizumab, a monoclonal antibody that targets the inflammatory cytokine interleukin-6 (IL-6), stabilized kidney transplant recipients' kidney function in a phase 2 trial.

27 Oct 2024

Novel gene therapy PS-002 targets podocytes in IgA nephropathy

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis.

27 Oct 2024

Novel multi-biomarker approach enhances chronic kidney disease risk assessment

Prior efforts to identify novel kidney biomarkers as risk factors for chronic kidney disease (CKD) progression have typically evaluated proteins individually, which limits their prognostic power.

26 Oct 2024

New trial shows felzartamab reduces proteinuria in IgA nephropathy patients

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface.

26 Oct 2024

New analysis confirms canagliflozin's cardiovascular and kidney benefits in older adults

Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of cardiovascular and kidney outcomes in patients with type 2 diabetes, but it is unclear whether their effects differ based on patients' age.

26 Oct 2024

Study: GLP-1RA not associated with acute kidney injury risk during anti-cancer treatments

Glucagon-like peptide-1-receptor agonists (GLP-1RA) are medications that are increasingly prescribed for patients with type 2 diabetes and congestive heart failure. Reports of GLP-1RA–associated acute kidney injury (AKI) have emerged, but the risk of GLP-1RA–associated AKI among patients on anti-cancer drugs is unclear.

26 Oct 2024

Global analysis reveals tripling of chronic kidney disease cases in women

A recent analysis reveals that the number of chronic kidney disease (CKD) cases in women around the globe nearly tripled in the past three decades.

26 Oct 2024

Kidney News and Research

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Survey reveals lack of awareness about pancreatic cancer risk among adults under age 50

Urine transcriptomics: A new frontier for non-invasive genitourinary disease detection

Could vitamin D be the missing link in managing type 2 diabetes? Recent study weighs in

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research identifies respiratory transmission potential of H5N1 virus

New genetic insights reveal kidney disease risk in West Africans

NIH grants $2.6 million to explore the effects of high blood-pressure drugs in CKD patients

Elucidating the mechanisms behind kidney development

How a proposed federal heat rule might have saved these workers’ lives

Study finds pistachios might help guard against vision loss

Ozempic effective for patients with chronic kidney damage

Clinical trial highlights efficacy of imlifidase for kidney transplant recipients

Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Novel gene therapy PS-002 targets podocytes in IgA nephropathy

Novel multi-biomarker approach enhances chronic kidney disease risk assessment

New trial shows felzartamab reduces proteinuria in IgA nephropathy patients

New analysis confirms canagliflozin's cardiovascular and kidney benefits in older adults

Study: GLP-1RA not associated with acute kidney injury risk during anti-cancer treatments

Global analysis reveals tripling of chronic kidney disease cases in women

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