Liver Transplant News and Research

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When a patient presents with end stage liver disease or liver failure he or she may be considered for a liver transplantation. The first step in this is often a rigorous assessment and being placed on a waiting list.

Gut bacterial metabolite linked to inflammation in liver disease

Researchers have identified a link between specific activities in gut bacteria and the liver disease PSC.

4 Sep 2026

Early-onset bowel cancer shows distinct biological and clinical features

One of Australia's largest real world studies of younger adults with advanced bowel cancer has identified important differences between cancers diagnosed before and after the age of 50, which could help doctors tailor treatments for younger adults more effectively.

1 Sep 2026

Combined bio-histological score prevents overtreatment in liver transplant patients

Long‑term outcomes after liver transplantation remain hampered by complications linked to intensive immunosuppression—infections, cardiovascular events, kidney dysfunction, and metabolic disorders affect 10% to 40% of recipients.

24 Aug 2026

Ochsner Transplant Institute completes historic 10,000th organ transplant

The Ochsner Transplant Institute has performed its 10,000th organ transplant, becoming the first and only transplant center in Louisiana to reach this milestone.

12 Aug 2026

New research agreement funds xenoliver transplant center at Baylor

Baylor College of Medicine today announced that a new research agreement with United Therapeutics Corporation, a public benefit corporation, will provide up to $5 million a year for five years to establish the Baylor College of Medicine Center for Xenoliver Transplantation and Immunomodulation (XTI), dedicated to advancing scientific understanding of xenoliver transplantation.

10 Aug 2026

Dual-compartment monitoring strategy improves evaluation of donor human livers

More than 100,000 people in the United States are waiting for a lifesaving organ transplant. For patients in need of a liver transplant, determining whether a donor liver is healthy enough to transplant is a critical part of the process.

14 Jul 2026

Immunotherapy helps bridge cancer patients to curative liver transplantation

Liver transplantation remains one of the most powerful curative options for hepatocellular carcinoma (HCC) because it removes both the tumor and the diseased liver.

22 Jun 2026

New EHR-based marker flags transplant patients at high risk for organ rejection

A new multicenter study led by researchers at the Icahn School of Medicine at Mount Sinai suggests that a novel electronic health record-based marker can help clinicians identify transplant patients at high risk for organ rejection due to not taking their medications as prescribed-and intervene before the rejection happens.

15 Jun 2026

New protocol prevents heavy alcohol relapse after liver transplantation

In a study published in the Liver Transplantation journal by the American Association for the Study of Liver Diseases, Mayo Clinic researchers found that a new proactive treatment protocol for alcohol use disorder after liver transplant resulted in a 0% heavy alcohol relapse rate among patients who followed the protocol, compared with a historical relapse rate of approximately 25%.

3 Jun 2026

BMI may miss millions with obesity-related conditions

Could the way doctors traditionally measure obesity allow a subset of people with obesity-related health risks slip through the cracks?

1 Jun 2026

Pioneering cell therapy offers hope for advanced liver disease

A new type of cell therapy shows promise as the first treatment for advanced liver disease, following results from a clinical trial.

25 May 2026

Recent advancements in the development of models to study primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a rare non-communicable disorder that affects the liver. Chronic inflammation in and around the bile duct is followed by the development of fibrotic obstructions within the duct, causing bile to accumulate within the liver.

19 May 2026

Synthetic biology approach boosts growth of implanted liver tissue

In patients developing end-stage liver disease, the damage has become too severe for the liver's normally extraordinary regenerative capacity to repair or compensate for it. Once this "point of no return" has been reached, the only option is an organ transplant.

17 Apr 2026

Donor-derived dendritic cells teach the immune system to accept new livers

UPMC and University of Pittsburgh clinician-scientists have weaned and kept multiple liver transplantation patients off of all immunosuppressant drugs for more than three years through a first-in-human clinical trial of a unique "immune priming" therapy.

17 Apr 2026

Rat hepatitis E virus may be a hidden cause of hepatitis in humans

This Nature Communications review argues that rat hepatitis E virus is an emerging zoonotic cause of hepatitis that is likely underdiagnosed because current tests are limited and awareness remains low. It shows that ratHEV is widespread in urban rodent populations, can infect humans and some other animals, and may spread mainly through indirect environmental exposure rather than direct rodent contact.

12 Apr 2026