Liver Cancer News and Research

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Liver cancer is more common in older people. Over half of people newly diagnosed with liver cancer are age 65 and over. Liver cancer is more common in men than in women. Liver cancer rates are highest among Asians and Pacific Islanders, most likely because of higher prevalence of viral Hepatitis infection. Liver cancer rates are lower among whites than Blacks or Asians and Pacific Islanders. At this time, we do not know exactly what causes cancer of the liver. There are several different types of liver cancer. The most common type is associated with long-term excessive alcoholic beverage use, scarring of the liver (cirrhosis), and Hepatitis B virus or Hepatitis C virus infection. Long-term use of anabolic steroids can also increase the risk of getting liver cancer. Smoking is also believed to increase the risk of getting liver cancer.

Evaluating the effectiveness of GAAD for early detection of hepatocellular carcinoma

Early detection of hepatocellular carcinoma (HCC) is crucial for improving survival in patients with chronic hepatitis.

25 Oct 2024

Tertiary lymphoid structures linked to improved outcomes in liver cancer patients

A newly described stage of a lymph node-like structure seen in liver tumors after presurgical immunotherapy may be vital to successfully treating patients with hepatocellular carcinoma, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center.

25 Oct 2024

New drug WNTinib shows promise in treating pediatric liver cancer

A new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of liver cancer that occurs in young children.

22 Oct 2024

Liver function discovery could revolutionize treatments for cardiovascular disease

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

18 Oct 2024

Study identifies biomarkers for immunotherapy success in liver cancer

It may soon be possible to determine which patients with a type of liver cancer called hepatocellular carcinoma would benefit from immunotherapy, according to a preclinical study by Weill Cornell Medicine investigators.

17 Oct 2024

New grant aims to transform treatment for liver cancer

Currently, there are a few available treatment options for liver cancer, including a combination of immunotherapies and a class of drugs known as tyrosine kinase inhibitors (TKIs), but their long-term effects are limited.

17 Oct 2024

Liver cancer patients gain clarity on surgery options through precision medicine tool

Duke-NUS alumnus Dr Marjorie Hoang (Class of 2023) and her mentor, Professor Pierce Chow, have brought clarity to the complex decision-making process patients diagnosed with intermediate-stage liver cancer and their doctors face by creating an algorithm that can accurately calculate the likely overall survival and recurrence-free survival following surgery.

9 Oct 2024

Environmental factors significantly impact gene expression through epigenetic modifications

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment. The review article "Epigenetics and Environmental Health" provides an in-depth analysis of how epigenetic modifications can influence the onset and progression of various diseases, particularly cancer and cardiovascular diseases.

8 Oct 2024

Study reveals gaps in hepatitis C treatment among reproductive-aged women

Most pediatric cases of hepatitis C virus (HCV) infection are perinatal, meaning the virus is transmitted from birthing parent to child during pregnancy or birth, according to the Centers for Disease Control and Prevention.

7 Oct 2024

Study links obesity and diabetes to higher recurrence rates in liver cancer

Hepatocellular carcinoma, a type of liver cancer associated with hepatitis infections, is known to have a high recurrence rate after cancer removal.

3 Oct 2024

Novel lipid nanoparticles enhance tissue-specific drug delivery

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era in personalized medicine and gene therapy.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

Study sheds light on mechanisms behind liver fibrosis and potential therapies

New research from the University of Pittsburgh School of Pharmacy sheds light on the processes that lead to liver fibrosis and suggests a novel treatment approach for this common and serious condition.

25 Sep 2024

PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

A promising new therapeutic target for MASLD identified

Using a novel stem cell platform, a team of the Medical University of South Carolina researchers has identified a pathway that could be targeted by drugs to reduce fat accumulation in patients with a common form of fatty liver disease known as metabolic dysfunction-associated steatotic liver disease, or MASLD.

11 Sep 2024

Scientists discover key to activating natural killer cells against cancer

Scientists are on the verge of a cancer breakthrough after working out how the body's immune system targets cells devastated by the disease.

28 Aug 2024

Researchers demonstrate a new method to combat pancreatic cancer

Researchers at the University of Massachusetts Amherst and UMass Chan Medical School have demonstrated in mice a new method to combat pancreatic cancer.

28 Aug 2024

New insights into macrophages' role in MASH and liver fibrosis

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

22 Aug 2024

Breakthrough treatment reduces liver fibrosis in Hepatitis C patients

HCV infection is the underlying cause for chronic Hepatitis C (CHC), liver cirrhosis, and liver cancer or hepatocellular carcinoma (HCC). In 2019, over 2,90,000 people died of HCV-related diseases. Recent medical advancement made a new breakthrough treatment available for patients with hepatitis C. DAAs that block replication of HCV has dramatically transformed the treatment approach with around 90% effective anti-viral response rates. However, it is unclear whether DAAs impact the severity of disease burden caused by liver fibrosis.

21 Aug 2024